STRINGSTRING
ATP6V0A1 ATP6V0A1 HLA-DPA1 HLA-DPA1 LOC105704667 LOC105704667 ATP6V1G1 ATP6V1G1 ENSANAP00000014481 ENSANAP00000014481 HLA-DQB2 HLA-DQB2 TNFSF11 TNFSF11 LOC105725360 LOC105725360 HLA-DMA HLA-DMA ATP6V0D1 ATP6V0D1 ATP6V1G3 ATP6V1G3 CD86 CD86 TRAC TRAC HLA-DQA2 HLA-DQA2 HLA-DOA HLA-DOA PTH PTH LOC105704663 LOC105704663 ENSANAP00000010134 ENSANAP00000010134 ATP6V0A4 ATP6V0A4 CTSL CTSL IL15 IL15 VEGFA VEGFA IL6 IL6 IL23A IL23A ENSANAP00000005537 ENSANAP00000005537 ENSANAP00000004890 ENSANAP00000004890 LOC105712514 LOC105712514 CSF2 CSF2 LOC105717178 LOC105717178 LOC105708942 LOC105708942 LOC105730458 LOC105730458 LOC105714732 LOC105714732 ATP6V1H ATP6V1H ENSANAP00000001461 ENSANAP00000001461 IFNG IFNG RELCH RELCH ENSANAP00000000736 ENSANAP00000000736 IL1B IL1B IL1A IL1A CSF1 CSF1 HLA-DPB1 HLA-DPB1 CCL5 CCL5 CCL2 CCL2 ATP6V0B ATP6V0B TNFSF13 TNFSF13 ENSANAP00000040170 ENSANAP00000040170 ATP6V1E1 ATP6V1E1 CTSK CTSK ANGPT1 ANGPT1 IL17A IL17A ATP6AP1 ATP6AP1 ENSANAP00000037255 ENSANAP00000037255 TGFB1 TGFB1 CXCL12 CXCL12 ATP6V1B1 ATP6V1B1 CD80 CD80 CXCL6 CXCL6 ATP6V0A2 ATP6V0A2 LOC105708941 LOC105708941 CXCL8 CXCL8 TNFRSF11A TNFRSF11A CXCL5 CXCL5 ATP6V1A ATP6V1A ITGAL ITGAL ACP5 ACP5 ATP6V1G2 ATP6V1G2 ATP6V1B2 ATP6V1B2 ITGB2 ITGB2 ENSANAP00000030041 ENSANAP00000030041 TGFB2 TGFB2 TCIRG1 TCIRG1 IL18 IL18 TNFSF13B TNFSF13B ATP6V0D2 ATP6V0D2 LOC105704661 LOC105704661 TEK TEK ATP6V0C ATP6V0C ATP6V1F ATP6V1F LOC105733430 LOC105733430 MMP3 MMP3 FOS FOS TGFB3 TGFB3 MMP1 MMP1 ATP6V1C1 ATP6V1C1 CTLA4 CTLA4 FLT1 FLT1 CD28 CD28 ATP6V0E2 ATP6V0E2 CXCL1 CXCL1 ATP6V1C2 ATP6V1C2 HLA-DRA HLA-DRA ATP6V1D ATP6V1D LTB LTB TLR4 TLR4 CCL20 CCL20 ENSANAP00000016399 ENSANAP00000016399 LOC110569300 LOC110569300 ATP6V0E1 ATP6V0E1 IL11 IL11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATP6V0A1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (837 aa)
HLA-DPA1Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (260 aa)
LOC105704667Ig-like domain-containing protein; Belongs to the MHC class II family. (262 aa)
ATP6V1G1V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
ENSANAP00000014481Ig-like domain-containing protein. (184 aa)
HLA-DQB2Major histocompatibility complex, class II, DQ beta 2. (274 aa)
TNFSF11Tumor necrosis factor ligand superfamily member. (317 aa)
LOC105725360C-X-C motif chemokine. (107 aa)
HLA-DMAMajor histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (261 aa)
ATP6V0D1V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (388 aa)
ATP6V1G3V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
CD86CD86 molecule. (331 aa)
TRACT cell receptor alpha constant. (134 aa)
HLA-DQA2Major histocompatibility complex, class II, DQ alpha 2; Belongs to the MHC class II family. (255 aa)
HLA-DOAMajor histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (250 aa)
PTHParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa)
LOC105704663Ig-like domain-containing protein. (271 aa)
ENSANAP00000010134Uncharacterized protein. (199 aa)
ATP6V0A4V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (805 aa)
CTSLCathepsin L; Belongs to the peptidase C1 family. (333 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (412 aa)
IL6Interleukin 6. (213 aa)
IL23AInterleukin 23 subunit alpha. (189 aa)
ENSANAP00000005537Ig-like domain-containing protein. (137 aa)
ENSANAP00000004890Ig-like domain-containing protein. (127 aa)
LOC105712514C-C motif chemokine. (93 aa)
CSF2Colony stimulating factor 2. (144 aa)
LOC105717178V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
LOC105708942Ig-like domain-containing protein. (318 aa)
LOC105730458Ig-like domain-containing protein; Belongs to the MHC class II family. (255 aa)
LOC105714732V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (112 aa)
ATP6V1HV-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (475 aa)
ENSANAP00000001461Uncharacterized protein. (209 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
RELCHRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1250 aa)
ENSANAP00000000736Uncharacterized protein. (229 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (231 aa)
CSF1Colony stimulating factor 1. (619 aa)
HLA-DPB1Major histocompatibility complex, class II, DP beta 1. (258 aa)
CCL5C-C motif chemokine. (91 aa)
CCL2C-C motif chemokine. (99 aa)
ATP6V0BATPase H+ transporting V0 subunit b; Belongs to the V-ATPase proteolipid subunit family. (252 aa)
TNFSF13TNF superfamily member 13; Belongs to the tumor necrosis factor family. (251 aa)
ENSANAP00000040170V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (116 aa)
ATP6V1E1Uncharacterized protein. (223 aa)
CTSKCathepsin K; Belongs to the peptidase C1 family. (329 aa)
ANGPT1Angiopoietin 1. (498 aa)
IL17AInterleukin 17A. (153 aa)
ATP6AP1ATPase H+ transporting accessory protein 1. (466 aa)
ENSANAP00000037255Uncharacterized protein. (316 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (378 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (128 aa)
ATP6V1B1Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)
CD80CD80 molecule. (289 aa)
CXCL6C-X-C motif chemokine. (114 aa)
ATP6V0A2V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (802 aa)
LOC105708941Ig-like domain-containing protein; Belongs to the MHC class II family. (255 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
TNFRSF11ATNF receptor superfamily member 11a. (620 aa)
CXCL5C-X-C motif chemokine. (107 aa)
ATP6V1AATPase H+ transporting V1 subunit A. (618 aa)
ITGALIntegrin subunit alpha L; Belongs to the integrin alpha chain family. (1204 aa)
ACP5Tartrate-resistant acid phosphatase type 5. (325 aa)
ATP6V1G2V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (158 aa)
ATP6V1B2Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (540 aa)
ITGB2Integrin beta. (739 aa)
ENSANAP00000030041Uncharacterized protein. (58 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (828 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
TNFSF13BTNF superfamily member 13b; Belongs to the tumor necrosis factor family. (320 aa)
ATP6V0D2V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (350 aa)
LOC105704661Ig-like domain-containing protein. (263 aa)
TEKTEK receptor tyrosine kinase. (1124 aa)
ATP6V0CV-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
ATP6V1FV-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (147 aa)
LOC105733430V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (376 aa)
MMP3Matrix metallopeptidase 3. (477 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
MMP1Matrix metallopeptidase 1. (469 aa)
ATP6V1C1V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (382 aa)
CTLA4Cytotoxic T-lymphocyte associated protein 4. (223 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa)
CD28CD28 molecule. (220 aa)
ATP6V0E2Uncharacterized protein. (130 aa)
CXCL1C-X-C motif chemokine. (107 aa)
ATP6V1C2V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (429 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa)
ATP6V1DATPase H+ transporting V1 subunit D. (247 aa)
LTBLymphotoxin beta; Belongs to the tumor necrosis factor family. (244 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (832 aa)
CCL20C-C motif chemokine. (96 aa)
ENSANAP00000016399Ig-like domain-containing protein. (137 aa)
LOC110569300V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (242 aa)
ATP6V0E1V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (81 aa)
IL11Interleukin 11. (199 aa)
Your Current Organism:
Aotus nancymaae
NCBI taxonomy Id: 37293
Other names: A. nancymaae, Aotus nancymai
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.