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| | ftsH | ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins. (627 aa) |
| | secG | Protein-export membrane protein secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (92 aa) |
| | plsC | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Identified by similarity to SP:P26647; match to protein family HMM PF01553; match to protein family HMM TIGR00530; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (249 aa) |
| | uppP | Putative undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (275 aa) |
| | BCI_0607 | Conserved hypothetical protein; Identified by similarity to GB:CAH19693.1; match to protein family HMM PF04357. (982 aa) |
| | pgpA | Phosphatidylglycerophosphatase; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). (168 aa) |
| | secF | Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecF subfamily. (306 aa) |
| | secD | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. (612 aa) |
| | yajC | Preprotein translocase YajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. (110 aa) |
| | hflK | HflK protein; HflC and HflK could encode or regulate a protease. (386 aa) |
| | hflC | HflC protein; HflC and HflK could regulate a protease. (333 aa) |
| | rlmB | RNA methyltransferase, TrmH family, group 3; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. (248 aa) |
| | BCI_0567 | Conserved hypothetical protein; Identified by match to protein family HMM PF03658; Belongs to the UPF0125 (RnfH) family. (109 aa) |
| | lspA | Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins. (167 aa) |
| | lgt | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (285 aa) |
| | bamA | Outer membrane protein, OMP85 family; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (793 aa) |
| | BCI_0534 | Protease EcfE; Identified by similarity to SP:P37764; match to protein family HMM PF00595; match to protein family HMM PF02163; match to protein family HMM TIGR00054. (459 aa) |
| | cdsA | Phosphatidate cytidylyltransferase; Identified by match to protein family HMM PF01148; Belongs to the CDS family. (284 aa) |
| | mraY | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan. (360 aa) |
| | BCI_0516 | Conserved hypothetical protein. (173 aa) |
| | secE | Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. (127 aa) |
| | emrA | Multidrug resistance protein; Identified by match to protein family HMM PF00529. (403 aa) |
| | BCI_0459 | Drug resistance transporter, EmrB/QacA subfamily; Identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711; Belongs to the major facilitator superfamily. (505 aa) |
| | BCI_0452 | Membrane protein, TerC family; Identified by match to protein family HMM PF00571; match to protein family HMM PF03741. (444 aa) |
| | BCI_0451 | PTS system, mannose/fructose/sorbose family, IIAB component; Identified by match to protein family HMM PF03610; match to protein family HMM PF03830; match to protein family HMM TIGR00824; match to protein family HMM TIGR00854. (322 aa) |
| | BCI_0450 | PTS system, mannose/fructose/sorbose family, IIC component; Identified by match to protein family HMM PF03609; match to protein family HMM TIGR00822. (266 aa) |
| | BCI_0449 | PTS system, mannose/fructose/sorbose family, IID component; Identified by similarity to SP:P08188; match to protein family HMM PF03613; match to protein family HMM TIGR00828. (279 aa) |
| | BCI_0448 | Conserved hypothetical protein; Identified by match to protein family HMM PF03734. (315 aa) |
| | sppA | Signal peptide peptidase SppA, 67K type; Identified by match to protein family HMM PF01343; match to protein family HMM TIGR00705; match to protein family HMM TIGR00706. (618 aa) |
| | BCI_0437 | Hypothetical protein; Identified by Glimmer2; putative. (33 aa) |
| | lolC | Lipoprotein releasing system, transmembrane protein LolC; Identified by similarity to SP:P75956; match to protein family HMM PF02687; match to protein family HMM TIGR02212. (397 aa) |
| | lolE | Lipoprotein releasing system, transmembrane protein LolE; Identified by similarity to SP:P75958; match to protein family HMM PF02687; match to protein family HMM TIGR02212. (415 aa) |
| | dsvC | Dissimilatory sulfite reductase, gamma subunit; Identified by match to protein family HMM PF04358. (163 aa) |
| | lysP | Lysine-specific permease; Identified by match to protein family HMM PF00324. (492 aa) |
| | nuoA | NADH-quinone oxidoreductase, subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family. (128 aa) |
| | nuoF | NADH-quinone oxidoreductase, F subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (444 aa) |
| | nuoH | NADH-quinone oxidoreductase, chain H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. (321 aa) |
| | nuoJ | NADH-quinone oxidoreductase, chain J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (165 aa) |
| | nuoK | NADH-quinone oxidoreductase, chain K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (100 aa) |
| | nuoL | Proton-translocating NADH-quinone oxidoreductase, chain L; Identified by match to protein family HMM PF00361; match to protein family HMM PF00662; match to protein family HMM TIGR01974. (621 aa) |
| | nuoM | Proton-translocating NADH-quinone oxidoreductase, chain M; Identified by similarity to SP:P31978; match to protein family HMM PF00361; match to protein family HMM TIGR01972. (507 aa) |
| | nuoN | Proton-translocating NADH-quinone oxidoreductase, chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (484 aa) |
| | cvpA | Identified by match to protein family HMM PF02674. (161 aa) |
| | secY | Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. Belongs to t [...] (444 aa) |
| | artM | Arginine ABC transporter, permease protein; Identified by similarity to SP:P30862; match to protein family HMM PF00528; match to protein family HMM TIGR01726. (223 aa) |
| | artQ | Arginine ABC transporter, permease protein; Identified by match to protein family HMM PF00528. (231 aa) |
| | ftsK | DNA translocase ftsK; Identified by match to protein family HMM PF01580; Belongs to the FtsK/SpoIIIE/SftA family. (666 aa) |
| | mntH | Mn2+/Fe2+ transporter, NRAMP family; H(+)-stimulated, divalent metal cation uptake system. (449 aa) |
| | htpX | Heat shock protein, integral membrane protein; Identified by match to protein family HMM PF01435; match to protein family HMM PF06509; Belongs to the peptidase M48B family. (291 aa) |
| | cls | Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily. (483 aa) |
| | BCI_0303 | Conserved hypothetical protein; Identified by match to protein family HMM PF06790. (254 aa) |
| | lapA | Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. (98 aa) |
| | lepB | Signal peptidase I; Identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227; Belongs to the peptidase S26 family. (311 aa) |
| | mviN | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (508 aa) |
| | BCI_0271 | Transporter, major facilitator family; Identified by match to protein family HMM PF00083; match to protein family HMM PF07690. (469 aa) |
| | cyoE | Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (288 aa) |
| | cyoC | Cytochrome o ubiquinol oxidase, subunit III; Identified by similarity to SP:P18402. (203 aa) |
| | cyoB | Ubiquinol oxidase, polypeptide I; Identified by similarity to SP:P18401; match to protein family HMM PF00115; Belongs to the heme-copper respiratory oxidase family. (665 aa) |
| | cyoA | Ubiquinol oxidase, subunit II; Identified by match to protein family HMM PF00116; match to protein family HMM PF06481; match to protein family HMM TIGR01433. (304 aa) |
| | pgsA | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Identified by match to protein family HMM PF01066; match to protein family HMM TIGR00560; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (187 aa) |
| | mdtH | Transporter, major facilitator family; Identified by match to protein family HMM PF07690. (402 aa) |
| | mrdB | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (363 aa) |
| | mrdA | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (621 aa) |
| | BCI_0208 | Amino acid ABC transporter, permease protein; Identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726. (218 aa) |
| | BCI_0200 | Hypothetical protein; Identified by Glimmer2; putative. (41 aa) |
| | BCI_0175 | Peptidase, M23 family; Identified by match to protein family HMM PF01551. (405 aa) |
| | BCI_0174 | Rhodanese domain protein; Identified by match to protein family HMM PF00581. (143 aa) |
| | atpB | ATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (273 aa) |
| | atpE | ATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (80 aa) |
| | atpF | ATP synthase F0, B subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (156 aa) |
| | yidC | Inner membrane protein oxaA; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins; Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily. (533 aa) |
| | BCI_0130 | Conserved hypothetical protein. (335 aa) |
| | corA | Magnesium and cobalt transport protein CorA; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family. (316 aa) |
| | BCI_0105 | Cation ABC transporter, permease protein; Identified by match to protein family HMM PF00950. (284 aa) |
| | BCI_0104 | Na+/H+ antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (552 aa) |
| | pal | Peptidoglycan-associated lipoprotein precursor; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. (211 aa) |
| | cysA | Sulfate ABC transporter, ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family. (377 aa) |
| | cysW | Sulfate ABC transporter, permease protein CysW; Identified by match to protein family HMM PF00528; match to protein family HMM TIGR00969; match to protein family HMM TIGR02140. (280 aa) |
| | cysT | Sulfate ABC transporter, permease protein CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (276 aa) |
| | zipA | Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. (269 aa) |
| | lnt | Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation. (506 aa) |
| | ftsX | Protein insertion permease FtsX; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. (316 aa) |
| | pitA | Low-affinity inorganic phosphate transporter; Identified by similarity to SP:P37308; match to protein family HMM PF01384. (524 aa) |
| | BCI_0053 | Membrane protein, MarC family; Identified by match to protein family HMM PF01914; match to protein family HMM TIGR00427; Belongs to the UPF0056 (MarC) family. (211 aa) |
| | mreC | Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape. (288 aa) |
| | mreD | Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family. (158 aa) |
| | BCI_0038 | Conserved hypothetical protein; Identified by match to protein family HMM PF01145. (300 aa) |
| | BCI_0033 | Conserved hypothetical protein TIGR00645; Identified by match to protein family HMM PF03350; match to protein family HMM TIGR00645. (164 aa) |
| | BCI_0030 | Conserved hypothetical protein; Identified by match to protein family HMM PF06295. (135 aa) |
| | BCI_0026 | Identified by match to protein family HMM PF00597. (216 aa) |
| | metA | Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family. (306 aa) |
| | BCI_0018 | RmuC domain protein; Identified by similarity to SP:P27850; match to protein family HMM PF02646. (494 aa) |
