(32 nodes) Endoplasmic reticulum unfolded protein response network (Malus domestica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DVH24_033460	Uncharacterized protein. (429 aa)
	DVH24_007147	Uncharacterized protein. (376 aa)
	DVH24_025101	Uncharacterized protein. (68 aa)
	DVH24_029387	Uncharacterized protein. (89 aa)
	DVH24_029388	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (211 aa)
	DVH24_040031	Uncharacterized protein; Belongs to the heat shock protein 70 family. (667 aa)
	DVH24_019359	UBA domain-containing protein. (285 aa)
	DVH24_041060	Uncharacterized protein. (86 aa)
	DVH24_005187	UBA domain-containing protein. (406 aa)
	DVH24_036598	Uncharacterized protein. (422 aa)
	DVH24_003382	OTU domain-containing protein. (207 aa)
	DVH24_017002	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (243 aa)
	DVH24_033461	Uncharacterized protein; Belongs to the heat shock protein 70 family. (621 aa)
	DVH24_014094	WD_REPEATS_REGION domain-containing protein. (302 aa)
	DVH24_016095	Uncharacterized protein. (186 aa)
	DVH24_016097	BZIP domain-containing protein. (741 aa)
	DVH24_033459	Uncharacterized protein; Belongs to the heat shock protein 70 family. (601 aa)
	DVH24_024551	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (276 aa)
	DVH24_016139	Uncharacterized protein. (688 aa)
	DVH24_024548	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (260 aa)
	DVH24_008283	Uncharacterized protein; Belongs to the heat shock protein 70 family. (731 aa)
	DVH24_010551	Uncharacterized protein. (146 aa)
	DVH24_009624	Uncharacterized protein; Belongs to the glycosyl hydrolase 17 family. (1367 aa)
	DVH24_035880	Uncharacterized protein. (333 aa)
	DVH24_011709	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (244 aa)
	DVH24_001207	Uncharacterized protein. (281 aa)
	DVH24_018042	Multifunctional fusion protein; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (391 aa)
	DVH24_006623	BZIP domain-containing protein. (976 aa)
	DVH24_017699	PRKCSH domain-containing protein. (290 aa)
	DVH24_026025	Uncharacterized protein. (480 aa)
	DVH24_018367	Uncharacterized protein. (884 aa)
	DVH24_015413	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (258 aa)

Your Current Organism:

Malus domestica

NCBI taxonomy Id: 3750
Other names: M. domestica, Malus communis, Malus communis Desf., Malus domestica Borkh., nom. cons. prop., Malus pumila auct., Malus pumila var. domestica, Malus pumila var. domestica (Borkh.) C.K.Schneid., Malus sylvestris var. domestica, Malus sylvestris var. domestica (Borkh.) Mansf., Malus x domestica, Pyrus malus, Pyrus malus L., apple, apple tree, cultivated apple

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DVH24_003382	DVH24_017699	A0A498IL53	A0A498KE73	OTU domain-containing protein.	PRKCSH domain-containing protein.	0.465
DVH24_006623	DVH24_009624	A0A498KDC7	A0A498JTA3	BZIP domain-containing protein.	Uncharacterized protein; Belongs to the glycosyl hydrolase 17 family.	0.524
DVH24_006623	DVH24_018367	A0A498KDC7	A0A498KKM9	BZIP domain-containing protein.	Uncharacterized protein.	0.524
DVH24_008283	DVH24_009624	A0A498JPK5	A0A498JTA3	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein; Belongs to the glycosyl hydrolase 17 family.	0.894
DVH24_008283	DVH24_010551	A0A498JPK5	A0A498JT45	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.573
DVH24_008283	DVH24_011709	A0A498JPK5	A0A498K0B8	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.573
DVH24_008283	DVH24_015413	A0A498JPK5	A0A498KP12	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.573
DVH24_008283	DVH24_017002	A0A498JPK5	A0A498IRV5	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.573
DVH24_008283	DVH24_017699	A0A498JPK5	A0A498KE73	Uncharacterized protein; Belongs to the heat shock protein 70 family.	PRKCSH domain-containing protein.	0.741
DVH24_008283	DVH24_018042	A0A498JPK5	A0A498KCD1	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Multifunctional fusion protein; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.573
DVH24_008283	DVH24_018367	A0A498JPK5	A0A498KKM9	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.894
DVH24_008283	DVH24_024548	A0A498JPK5	A0A498JLT7	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.573
DVH24_008283	DVH24_024551	A0A498JPK5	A0A498JJ05	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.573
DVH24_008283	DVH24_029387	A0A498JPK5	A0A498HTA4	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.573
DVH24_008283	DVH24_029388	A0A498JPK5	A0A498HYK5	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.573
DVH24_008283	DVH24_040031	A0A498JPK5	A0A498I4B3	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.900
DVH24_009624	DVH24_006623	A0A498JTA3	A0A498KDC7	Uncharacterized protein; Belongs to the glycosyl hydrolase 17 family.	BZIP domain-containing protein.	0.524
DVH24_009624	DVH24_008283	A0A498JTA3	A0A498JPK5	Uncharacterized protein; Belongs to the glycosyl hydrolase 17 family.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.894
DVH24_009624	DVH24_016095	A0A498JTA3	A0A498JEA6	Uncharacterized protein; Belongs to the glycosyl hydrolase 17 family.	Uncharacterized protein.	0.524
DVH24_009624	DVH24_016097	A0A498JTA3	A0A498JET3	Uncharacterized protein; Belongs to the glycosyl hydrolase 17 family.	BZIP domain-containing protein.	0.524

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