(55 nodes) Misfolded protein binding network (Malus domestica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DVH24_017681	Uncharacterized protein. (343 aa)
	DVH24_031147	Uncharacterized protein. (133 aa)
	DVH24_024265	Uncharacterized protein. (123 aa)
	DVH24_024135	Uncharacterized protein. (402 aa)
	DVH24_024548	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (260 aa)
	DVH24_024551	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (276 aa)
	DVH24_024131	Uncharacterized protein. (116 aa)
	DVH24_024129	Uncharacterized protein. (495 aa)
	DVH24_024130	Uncharacterized protein. (77 aa)
	DVH24_024132	Uncharacterized protein. (86 aa)
	DVH24_033459	Uncharacterized protein; Belongs to the heat shock protein 70 family. (601 aa)
	DVH24_033460	Uncharacterized protein. (429 aa)
	DVH24_033461	Uncharacterized protein; Belongs to the heat shock protein 70 family. (621 aa)
	DVH24_020416	Uncharacterized protein. (319 aa)
	DVH24_035479	LRAT domain-containing protein. (254 aa)
	DVH24_002500	Uncharacterized protein; Belongs to the heat shock protein 70 family. (677 aa)
	DVH24_031149	Uncharacterized protein. (125 aa)
	DVH24_017002	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (243 aa)
	DVH24_032832	Uncharacterized protein. (247 aa)
	DVH24_036598	Uncharacterized protein. (422 aa)
	DVH24_005187	UBA domain-containing protein. (406 aa)
	DVH24_034925	Uncharacterized protein. (323 aa)
	DVH24_005129	Uncharacterized protein. (171 aa)
	DVH24_034927	Uncharacterized protein. (110 aa)
	DVH24_004460	Uncharacterized protein. (242 aa)
	DVH24_019191	Uncharacterized protein. (88 aa)
	DVH24_019359	UBA domain-containing protein. (285 aa)
	DVH24_019189	Uncharacterized protein. (105 aa)
	DVH24_040031	Uncharacterized protein; Belongs to the heat shock protein 70 family. (667 aa)
	DVH24_019287	LRAT domain-containing protein. (334 aa)
	DVH24_029388	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (211 aa)
	DVH24_029058	Ubiquitin-like domain-containing protein. (840 aa)
	DVH24_013059	Ubiquitin-like domain-containing protein. (1216 aa)
	DVH24_029387	Uncharacterized protein. (89 aa)
	DVH24_013308	Uncharacterized protein; Belongs to the heat shock protein 70 family. (569 aa)
	DVH24_031150	Uncharacterized protein. (133 aa)
	DVH24_031148	Uncharacterized protein. (133 aa)
	DVH24_030775	LRAT domain-containing protein. (247 aa)
	DVH24_023107	Uncharacterized protein. (235 aa)
	DVH24_023099	Uncharacterized protein. (148 aa)
	DVH24_015413	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (258 aa)
	DVH24_023100	Uncharacterized protein. (1055 aa)
	DVH24_023101	Uncharacterized protein. (125 aa)
	DVH24_023102	Uncharacterized protein. (187 aa)
	DVH24_023103	Uncharacterized protein. (121 aa)
	DVH24_014663	Uncharacterized protein. (138 aa)
	DVH24_017685	Ubiquitin-like domain-containing protein. (788 aa)
	DVH24_017683	Uncharacterized protein. (126 aa)
	DVH24_018042	Multifunctional fusion protein; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (391 aa)
	DVH24_038681	Uncharacterized protein. (63 aa)
	DVH24_026791	Uncharacterized protein. (243 aa)
	DVH24_037952	Uncharacterized protein; Belongs to the heat shock protein 70 family. (676 aa)
	DVH24_011709	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (244 aa)
	DVH24_010551	Uncharacterized protein. (146 aa)
	DVH24_008283	Uncharacterized protein; Belongs to the heat shock protein 70 family. (731 aa)

Your Current Organism:

Malus domestica

NCBI taxonomy Id: 3750
Other names: M. domestica, Malus communis, Malus communis Desf., Malus domestica Borkh., nom. cons. prop., Malus pumila auct., Malus pumila var. domestica, Malus pumila var. domestica (Borkh.) C.K.Schneid., Malus sylvestris var. domestica, Malus sylvestris var. domestica (Borkh.) Mansf., Malus x domestica, Pyrus malus, Pyrus malus L., apple, apple tree, cultivated apple

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DVH24_002500	DVH24_004460	A0A498IU20	A0A498IAU2	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.527
DVH24_002500	DVH24_005129	A0A498IU20	A0A498IGG5	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.508
DVH24_002500	DVH24_008283	A0A498IU20	A0A498JPK5	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.587
DVH24_002500	DVH24_013308	A0A498IU20	A0A498HKY2	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.520
DVH24_002500	DVH24_014663	A0A498IU20	A0A498KKU4	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.447
DVH24_002500	DVH24_019189	A0A498IU20	A0A498I4B4	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.447
DVH24_002500	DVH24_019191	A0A498IU20	A0A498I5C2	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.447
DVH24_002500	DVH24_019287	A0A498IU20	A0A498I0G5	Uncharacterized protein; Belongs to the heat shock protein 70 family.	LRAT domain-containing protein.	0.447
DVH24_002500	DVH24_023099	A0A498IU20	A0A498KTB1	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.502
DVH24_002500	DVH24_023100	A0A498IU20	A0A498KN63	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.555
DVH24_002500	DVH24_023101	A0A498IU20	A0A498KN44	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.489
DVH24_002500	DVH24_023102	A0A498IU20	A0A498KMH4	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.522
DVH24_002500	DVH24_023103	A0A498IU20	A0A498KLC3	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.447
DVH24_002500	DVH24_023107	A0A498IU20	A0A498KVK8	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.532
DVH24_002500	DVH24_024129	A0A498IU20	A0A498JHQ8	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.545
DVH24_002500	DVH24_024130	A0A498IU20	A0A498JH16	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.447
DVH24_002500	DVH24_024131	A0A498IU20	A0A498JI07	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.472
DVH24_002500	DVH24_024132	A0A498IU20	A0A498JFJ6	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.464
DVH24_002500	DVH24_024135	A0A498IU20	A0A498JMB6	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.540
DVH24_002500	DVH24_024265	A0A498IU20	A0A498JMP1	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.499

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