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| | nusA | Transcription termination protein NusA; Participates in both transcription termination and antitermination. (536 aa) |
| | BF49_0051 | Translation initiation factor 2. (594 aa) |
| | BF49_0053 | Transcription termination protein NusA. (536 aa) |
| | rpsO | SSU ribosomal protein S15p S13e; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. (89 aa) |
| | BF49_0100 | SSU ribosomal protein S1p; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. (568 aa) |
| | infC | Translation initiation factor 3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. (200 aa) |
| | rpmI | LSU ribosomal protein L35p; Belongs to the bacterial ribosomal protein bL35 family. (66 aa) |
| | rplT | LSU ribosomal protein L20p; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (119 aa) |
| | rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (421 aa) |
| | rplS | LSU ribosomal protein L19p; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (128 aa) |
| | trmD | tRNA Guanine37N1 methyltransferase EC 21131; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (251 aa) |
| | rimM | 16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (192 aa) |
| | rpsP | SSU ribosomal protein S16p; Belongs to the bacterial ribosomal protein bS16 family. (110 aa) |
| | rpmA | LSU ribosomal protein L27p; Belongs to the bacterial ribosomal protein bL27 family. (89 aa) |
| | rplU | LSU ribosomal protein L21p; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (129 aa) |
| | rpmB | LSU ribosomal protein L28p; Belongs to the bacterial ribosomal protein bL28 family. (103 aa) |
| | efp | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. (188 aa) |
| | rpsF | SSU ribosomal protein S6p; Binds together with S18 to 16S ribosomal RNA. (170 aa) |
| | rpsR | SSU ribosomal protein S18p SSU ribosomal protein S18p zincindependent; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (79 aa) |
| | rplI | LSU ribosomal protein L9p; Binds to the 23S rRNA. (201 aa) |
| | BF49_1989 | Hypothetical protein. (406 aa) |
| | rpoD | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (716 aa) |
| | BF49_2939 | Translation elongation factor Grelated protein. (651 aa) |
| | rplY | LSU ribosomal protein L25p; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (239 aa) |
| | rpmJ | LSU ribosomal protein L36p; Belongs to the bacterial ribosomal protein bL36 family. (41 aa) |
| | rpmH | LSU ribosomal protein L34p; Belongs to the bacterial ribosomal protein bL34 family. (44 aa) |
| | rnpA | Ribonuclease P protein component EC 31265; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (146 aa) |
| | BF49_3600 | Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination. (227 aa) |
| | map | Methionine aminopeptidase EC 341118; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. (272 aa) |
| | infA | Translation initiation factor 1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (95 aa) |
| | rpmE | LSU ribosomal protein L31p LSU ribosomal protein L31p zincindependent; Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily. (75 aa) |
| | rpsU | SSU ribosomal protein S21p; Belongs to the bacterial ribosomal protein bS21 family. (108 aa) |
| | BF49_5893 | DNAdirected RNA polymerase alpha subunit EC 2776. (269 aa) |
| | BF49_5901 | DNAdirected RNA polymerase alpha subunit EC 2776. (269 aa) |
| | rpsD | SSU ribosomal protein S4p S9e; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (191 aa) |
| | nusG | Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination. (184 aa) |
| | rplK | LSU ribosomal protein L11p L12e; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (142 aa) |
| | rplA | LSU ribosomal protein L1p L10Ae; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (230 aa) |
| | rplJ | LSU ribosomal protein L10p P0; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (190 aa) |
| | rplL | LSU ribosomal protein L7L12 P1P2; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (125 aa) |
| | rpoB | DNAdirected RNA polymerase beta subunit EC 2776; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1371 aa) |
| | rpoC | DNAdirected RNA polymerase beta subunit EC 2776; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1393 aa) |
| | rpsL | SSU ribosomal protein S12p S23e; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (123 aa) |
| | rpsG | SSU ribosomal protein S7p S5e; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa) |
| | fusA | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] (690 aa) |
| | tuf | Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (396 aa) |
| | rpsJ | SSU ribosomal protein S10p S20e; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa) |
| | rplC | LSU ribosomal protein L3p L3e; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (237 aa) |
| | rplD | LSU ribosomal protein L4p L1e; Forms part of the polypeptide exit tunnel. (206 aa) |
| | rplW | LSU ribosomal protein L23p L23Ae; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (100 aa) |
| | rplB | LSU ribosomal protein L2p L8e; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (277 aa) |
| | rpsS | SSU ribosomal protein S19p S15e; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (92 aa) |
| | rplV | LSU ribosomal protein L22p L17e; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (128 aa) |
| | rpsC | SSU ribosomal protein S3p S3e; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (241 aa) |
| | rplP | LSU ribosomal protein L16p L10e; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (137 aa) |
| | rpmC | LSU ribosomal protein L29p L35e; Belongs to the universal ribosomal protein uL29 family. (68 aa) |
| | rpsQ | SSU ribosomal protein S17p S11e; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (77 aa) |
| | rplN | LSU ribosomal protein L14p L23e; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa) |
| | rplX | LSU ribosomal protein L24p L26e; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (104 aa) |
| | rplE | LSU ribosomal protein L5p L11e; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (185 aa) |
| | rpsN | SSU ribosomal protein S14p S29e SSU ribosomal protein S14p S29e zincindependent; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (101 aa) |
| | rpsH | SSU ribosomal protein S8p S15Ae; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (132 aa) |
| | rplF | LSU ribosomal protein L6p L9e; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (177 aa) |
| | rplR | LSU ribosomal protein L18p L5e; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (120 aa) |
| | rpsE | SSU ribosomal protein S5p S2e; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (195 aa) |
| | rpmD | LSU ribosomal protein L30p L7e. (68 aa) |
| | rplO | LSU ribosomal protein L15p L27Ae; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (161 aa) |
| | rpsM | SSU ribosomal protein S13p S18e; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (122 aa) |
| | rpsK | SSU ribosomal protein S11p S14e; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (129 aa) |
| | rpoA | DNAdirected RNA polymerase alpha subunit EC 2776; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (339 aa) |
| | rplQ | LSU ribosomal protein L17p. (138 aa) |
| | rpmG | LSU ribosomal protein L33p LSU ribosomal protein L33p zincindependent; Belongs to the bacterial ribosomal protein bL33 family. (55 aa) |
| | rpoZ | DNAdirected RNA polymerase omega subunit EC 2776; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (130 aa) |
| | BF49_6559 | Conserved hypothetical protein gene in Ubiquinolcytochrome C chaperone locus. (173 aa) |
| | rplM | LSU ribosomal protein L13p L13Ae; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (154 aa) |
| | rpsI | SSU ribosomal protein S9p S16e; Belongs to the universal ribosomal protein uS9 family. (159 aa) |
| | tig | Cell division trigger factor EC 5218; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (456 aa) |
| | rpsB | SSU ribosomal protein S2p SAe; Belongs to the universal ribosomal protein uS2 family. (330 aa) |
| | tsf | Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. (307 aa) |
| | frr | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (187 aa) |
| | rpmF | LSU ribosomal protein L32p; Belongs to the bacterial ribosomal protein bL32 family. (60 aa) |
| | rpsT | SSU ribosomal protein S20p; Binds directly to 16S ribosomal RNA. (88 aa) |
| | BF49_7371 | SSU ribosomal protein S15p S13e. (89 aa) |
| | BF49_7372 | SSU ribosomal protein S15p S13e. (89 aa) |
| | BF49_7376 | Translation initiation factor 2. (96 aa) |
| | BF49_7379 | SSU ribosomal protein S15p S13e. (89 aa) |
