(22 nodes) Ribonuclease H superfamily network (Halomonas gudaonensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rnd	Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family. (376 aa)
	SDI88725.1	Transposase and inactivated derivatives, IS30 family. (329 aa)
	rnhB	RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (208 aa)
	SDJ21619.1	Exodeoxyribonuclease I subunit C. (496 aa)
	SDJ22384.1	Hypothetical protein. (166 aa)
	ruvC	Holliday junction endonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (179 aa)
	SDJ51122.1	DNA polymerase-3 subunit epsilon. (209 aa)
	SDJ47843.1	DNA polymerase-3 subunit epsilon. (241 aa)
	SDJ57881.1	Putative transposase. (259 aa)
	SDJ60249.1	Transposase InsO and inactivated derivatives. (288 aa)
	SDK81729.1	Transposase InsO and inactivated derivatives. (220 aa)
	SDK80773.1	Integrase core domain-containing protein. (343 aa)
	rnhA-2	Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (185 aa)
	SDK59695.1	DNA polymerase-3 subunit epsilon. (687 aa)
	rnt	Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. (221 aa)
	SDK30720.1	Putative transposase. (693 aa)
	orn	Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family. (197 aa)
	polA	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (920 aa)
	SDJ95046.1	Integrase core domain-containing protein. (103 aa)
	rnhA	Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (162 aa)
	dnaQ	DNA polymerase-3 subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (253 aa)
	SDJ60928.1	Transposase and inactivated derivatives, IS30 family. (254 aa)

Your Current Organism:

Halomonas gudaonensis

NCBI taxonomy Id: 376427
Other names: CGMCC 1.6133, H. gudaonensis, Halomonas gudaonensis Wang et al. 2007, LMG 23610, LMG:23610, strain SL014B-69

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SDI88725.1	SDJ57881.1	SAMN04487954_1023	SAMN04487954_1061	Transposase and inactivated derivatives, IS30 family.	Putative transposase.	0.448
SDJ22384.1	SDK59695.1	SAMN04487954_103376	SAMN04487954_12036	Hypothetical protein.	DNA polymerase-3 subunit epsilon.	0.589
SDJ22384.1	polA	SAMN04487954_103376	SAMN04487954_11169	Hypothetical protein.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.526
SDJ47843.1	SDJ51122.1	SAMN04487954_10541	SAMN04487954_105131	DNA polymerase-3 subunit epsilon.	DNA polymerase-3 subunit epsilon.	0.938
SDJ47843.1	SDK59695.1	SAMN04487954_10541	SAMN04487954_12036	DNA polymerase-3 subunit epsilon.	DNA polymerase-3 subunit epsilon.	0.942
SDJ47843.1	polA	SAMN04487954_10541	SAMN04487954_11169	DNA polymerase-3 subunit epsilon.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.534
SDJ51122.1	SDJ47843.1	SAMN04487954_105131	SAMN04487954_10541	DNA polymerase-3 subunit epsilon.	DNA polymerase-3 subunit epsilon.	0.938
SDJ51122.1	SDK59695.1	SAMN04487954_105131	SAMN04487954_12036	DNA polymerase-3 subunit epsilon.	DNA polymerase-3 subunit epsilon.	0.944
SDJ51122.1	polA	SAMN04487954_105131	SAMN04487954_11169	DNA polymerase-3 subunit epsilon.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.534
SDJ57881.1	SDI88725.1	SAMN04487954_1061	SAMN04487954_1023	Putative transposase.	Transposase and inactivated derivatives, IS30 family.	0.448
SDK59695.1	SDJ22384.1	SAMN04487954_12036	SAMN04487954_103376	DNA polymerase-3 subunit epsilon.	Hypothetical protein.	0.589
SDK59695.1	SDJ47843.1	SAMN04487954_12036	SAMN04487954_10541	DNA polymerase-3 subunit epsilon.	DNA polymerase-3 subunit epsilon.	0.942
SDK59695.1	SDJ51122.1	SAMN04487954_12036	SAMN04487954_105131	DNA polymerase-3 subunit epsilon.	DNA polymerase-3 subunit epsilon.	0.944
SDK59695.1	dnaQ	SAMN04487954_12036	SAMN04487954_10865	DNA polymerase-3 subunit epsilon.	DNA polymerase-3 subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	0.944
SDK59695.1	polA	SAMN04487954_12036	SAMN04487954_11169	DNA polymerase-3 subunit epsilon.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.699
SDK59695.1	rnt	SAMN04487954_12036	SAMN04487954_12028	DNA polymerase-3 subunit epsilon.	Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.	0.615
dnaQ	SDK59695.1	SAMN04487954_10865	SAMN04487954_12036	DNA polymerase-3 subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	DNA polymerase-3 subunit epsilon.	0.944
dnaQ	orn	SAMN04487954_10865	SAMN04487954_11446	DNA polymerase-3 subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.	0.563
dnaQ	polA	SAMN04487954_10865	SAMN04487954_11169	DNA polymerase-3 subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.592
dnaQ	rnhA	SAMN04487954_10865	SAMN04487954_10866	DNA polymerase-3 subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.965