STRINGSTRING
SDJ88676.1 SDJ88676.1 SDJ18687.1 SDJ18687.1 mutS mutS SDJ16565.1 SDJ16565.1 ligA ligA xseA xseA SDI92294.1 SDI92294.1 rep rep SDJ21045.1 SDJ21045.1 dnaQ dnaQ SDJ81541.1 SDJ81541.1 SDJ70688.1 SDJ70688.1 lexA lexA SDJ48845.1 SDJ48845.1 SDJ47843.1 SDJ47843.1 SDJ51122.1 SDJ51122.1 SDJ46723.1 SDJ46723.1 SDI97717.1 SDI97717.1 SDK24192.1 SDK24192.1 mutL mutL SDK36530.1 SDK36530.1 SDK42889.1 SDK42889.1 SDK47448.1 SDK47448.1 ligB ligB rnt rnt SDK59695.1 SDK59695.1 SDK67388.1 SDK67388.1 SDK68852.1 SDK68852.1 SDK75079.1 SDK75079.1 SDK78486.1 SDK78486.1 SDJ38546.1 SDJ38546.1 SDJ11592.1 SDJ11592.1 SDJ10280.1 SDJ10280.1 SDJ22384.1 SDJ22384.1 SDJ21619.1 SDJ21619.1 SDJ01156.1 SDJ01156.1 SDI89909.1 SDI89909.1 dnaX dnaX SDI77689.1 SDI77689.1 SDI77850.1 SDI77850.1 SDI78054.1 SDI78054.1 xseB xseB SDK25080.1 SDK25080.1 SDK24760.1 SDK24760.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SDJ88676.1Hypothetical protein. (113 aa)
SDJ18687.1DNA polymerase-3 subunit alpha. (1167 aa)
mutSDNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (859 aa)
SDJ16565.1Repressor LexA; Belongs to the peptidase S24 family. (158 aa)
ligADNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (689 aa)
xseAExodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (446 aa)
SDI92294.1DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] (367 aa)
repATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. (683 aa)
SDJ21045.1single-stranded-DNA-specific exonuclease. (601 aa)
dnaQDNA polymerase-3 subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (253 aa)
SDJ81541.1Peptidyl-prolyl cis-trans isomerase D. (605 aa)
SDJ70688.1Protein of unknown function. (387 aa)
lexARepressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (214 aa)
SDJ48845.1Peptidyl-prolyl cis-trans isomerase SurA. (225 aa)
SDJ47843.1DNA polymerase-3 subunit epsilon. (241 aa)
SDJ51122.1DNA polymerase-3 subunit epsilon. (209 aa)
SDJ46723.1Single-strand DNA-binding protein. (144 aa)
SDI97717.1Peptidyl-prolyl cis-trans isomerase C. (273 aa)
SDK24192.1Hypothetical protein. (135 aa)
mutLDNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (636 aa)
SDK36530.1Hypothetical protein. (71 aa)
SDK42889.1Metallo-beta-lactamase family protein. (469 aa)
SDK47448.1Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. (181 aa)
ligBDNA ligase (NAD+); Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. Belongs to the NAD-dependent DNA ligase family. LigB subfamily. (558 aa)
rntRibonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. (221 aa)
SDK59695.1DNA polymerase-3 subunit epsilon. (687 aa)
SDK67388.1Hypothetical protein. (117 aa)
SDK68852.1Single-strand DNA-binding protein. (141 aa)
SDK75079.1Protein of unknown function. (409 aa)
SDK78486.1Superoxide dismutase, Fe-Mn family; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (192 aa)
SDJ38546.1DNA polymerase III, delta subunit. (352 aa)
SDJ11592.1SOS response UmuD protein. Serine peptidase. MEROPS family S24; Belongs to the peptidase S24 family. (155 aa)
SDJ10280.1Metallo-beta-lactamase family protein. (468 aa)
SDJ22384.1Hypothetical protein. (166 aa)
SDJ21619.1Exodeoxyribonuclease I subunit C. (496 aa)
SDJ01156.1CRISPR-associated exonuclease Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family. (212 aa)
SDI89909.1DNA helicase-2 / ATP-dependent DNA helicase PcrA. (735 aa)
dnaXDNA polymerase III, gamma subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (645 aa)
SDI77689.1DNA polymerase-3 subunit delta'. (337 aa)
SDI77850.1DNA helicase-2 / ATP-dependent DNA helicase PcrA. (732 aa)
SDI78054.1Superoxide dismutase, Fe-Mn family; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (203 aa)
xseBExodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (96 aa)
SDK25080.1DNA polymerase III, chi subunit. (146 aa)
SDK24760.1Metallo-beta-lactamase superfamily protein. (347 aa)
Your Current Organism:
Halomonas gudaonensis
NCBI taxonomy Id: 376427
Other names: CGMCC 1.6133, H. gudaonensis, Halomonas gudaonensis Wang et al. 2007, LMG 23610, LMG:23610, strain SL014B-69
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