STRINGSTRING
accA accA Fjoh_0066 Fjoh_0066 Fjoh_0644 Fjoh_0644 Fjoh_0645 Fjoh_0645 Fjoh_0881 Fjoh_0881 Fjoh_1141 Fjoh_1141 Fjoh_1225 Fjoh_1225 pckA pckA accD accD Fjoh_1475 Fjoh_1475 Fjoh_1552 Fjoh_1552 pdhA pdhA Fjoh_1651 Fjoh_1651 Fjoh_1738 Fjoh_1738 Fjoh_1917 Fjoh_1917 Fjoh_2133 Fjoh_2133 mdh mdh mqo mqo Fjoh_2806 Fjoh_2806 Fjoh_2859 Fjoh_2859 Fjoh_2865 Fjoh_2865 Fjoh_2967 Fjoh_2967 Fjoh_3321 Fjoh_3321 ackA ackA Fjoh_3529 Fjoh_3529 Fjoh_4612 Fjoh_4612 Fjoh_4676 Fjoh_4676 Fjoh_4713 Fjoh_4713 fumC fumC Fjoh_4881 Fjoh_4881
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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Your Input:
accAacetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (317 aa)
Fjoh_0066PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase. (131 aa)
Fjoh_0644acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (448 aa)
Fjoh_0645acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (162 aa)
Fjoh_0881Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (534 aa)
Fjoh_1141PFAM: pyruvate kinase; Belongs to the pyruvate kinase family. (477 aa)
Fjoh_1225PFAM: aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (517 aa)
pckAPhosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (534 aa)
accDacetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (284 aa)
Fjoh_1475Transketolase, central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (325 aa)
Fjoh_1552TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein. (545 aa)
pdhAPyruvate dehydrogenase (acetyl-transferring); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (332 aa)
Fjoh_1651Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+))., Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic enzyme domain protein; malic enzyme, NAD-binding. (763 aa)
Fjoh_1738TIGRFAM: malate synthase A; PFAM: malate synthase; Belongs to the malate synthase family. (540 aa)
Fjoh_1917PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. (333 aa)
Fjoh_2133TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein. (467 aa)
mdhMalate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (311 aa)
mqoTIGRFAM: malate--quinone oxidoreductase; PFAM: FAD dependent oxidoreductase; Malate:quinone-oxidoreductase. (497 aa)
Fjoh_2806Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (861 aa)
Fjoh_2859Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (636 aa)
Fjoh_2865PFAM: pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (393 aa)
Fjoh_2967PFAM: aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (501 aa)
Fjoh_33213-ketoacyl-CoA thiolase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (426 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (394 aa)
Fjoh_3529Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (697 aa)
Fjoh_4612TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal domain protein; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
Fjoh_4676TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD dependent oxidoreductase. (462 aa)
Fjoh_4713PFAM: aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (442 aa)
fumCFumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (461 aa)
Fjoh_4881PFAM: beta-lactamase domain protein; SMART: Rhodanese domain protein. (471 aa)
Your Current Organism:
Flavobacterium johnsoniae
NCBI taxonomy Id: 376686
Other names: F. johnsoniae UW101, Flavobacterium johnsoniae ATCC 17061, Flavobacterium johnsoniae DSM 2064, Flavobacterium johnsoniae IAM 14304, Flavobacterium johnsoniae IFO 14942, Flavobacterium johnsoniae MYX.1.1.1, Flavobacterium johnsoniae NBRC 14942, Flavobacterium johnsoniae NCIB 11054, Flavobacterium johnsoniae UW101, Flavobacterium johnsoniae str. UW101, Flavobacterium johnsoniae strain UW101
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