node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATP_00026 | hsdM | ATP_00026 | ATP_00220 | N-6 adenine specific DNA methyltransferase; Paralog group: ATP_00026, ATP_00472 similar to ATP_00262. | Type I restriction-modification system, methyltransferase subunit. | 0.959 |
ATP_00262 | hsdM | ATP_00262 | ATP_00220 | N-6 adenine specific DNA methyltransferase. | Type I restriction-modification system, methyltransferase subunit. | 0.959 |
ATP_00472 | hsdM | ATP_00472 | ATP_00220 | N-6 adenine specific DNA methyltransferase; Paralog group: ATP_00026, ATP_00472 similar to ATP_00262. | Type I restriction-modification system, methyltransferase subunit. | 0.959 |
hsdM | ATP_00026 | ATP_00220 | ATP_00026 | Type I restriction-modification system, methyltransferase subunit. | N-6 adenine specific DNA methyltransferase; Paralog group: ATP_00026, ATP_00472 similar to ATP_00262. | 0.959 |
hsdM | ATP_00262 | ATP_00220 | ATP_00262 | Type I restriction-modification system, methyltransferase subunit. | N-6 adenine specific DNA methyltransferase. | 0.959 |
hsdM | ATP_00472 | ATP_00220 | ATP_00472 | Type I restriction-modification system, methyltransferase subunit. | N-6 adenine specific DNA methyltransferase; Paralog group: ATP_00026, ATP_00472 similar to ATP_00262. | 0.959 |
ksgA | mraW | ATP_00226 | ATP_00449 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Methyltransferase involved in cell envelope biogenesis; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.699 |
ksgA | spoU | ATP_00226 | ATP_00212 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | tRNA/rRNA methyltransferase. | 0.409 |
ksgA | thyA | ATP_00226 | ATP_00320 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.447 |
ksgA | tpm | ATP_00226 | ATP_00375 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Tetrapyrrole (Corrin/Porphyrin) methylase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.792 |
ksgA | trmD | ATP_00226 | ATP_00439 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.506 |
mraW | ksgA | ATP_00449 | ATP_00226 | Methyltransferase involved in cell envelope biogenesis; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.699 |
mraW | tpm | ATP_00449 | ATP_00375 | Methyltransferase involved in cell envelope biogenesis; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | Tetrapyrrole (Corrin/Porphyrin) methylase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.637 |
spoU | ksgA | ATP_00212 | ATP_00226 | tRNA/rRNA methyltransferase. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.409 |
thyA | ksgA | ATP_00320 | ATP_00226 | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.447 |
tpm | ksgA | ATP_00375 | ATP_00226 | Tetrapyrrole (Corrin/Porphyrin) methylase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.792 |
tpm | mraW | ATP_00375 | ATP_00449 | Tetrapyrrole (Corrin/Porphyrin) methylase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | Methyltransferase involved in cell envelope biogenesis; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.637 |
tpm | trmD | ATP_00375 | ATP_00439 | Tetrapyrrole (Corrin/Porphyrin) methylase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.495 |
tpm | trmU | ATP_00375 | ATP_00182 | Tetrapyrrole (Corrin/Porphyrin) methylase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | tRNA (5-methylaminomethyl-2-thioruidylate) methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.434 |
trmD | ksgA | ATP_00439 | ATP_00226 | tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.506 |