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hemF hemF hemC hemC hemD hemD ACR11481.1 ACR11481.1 ACR11132.1 ACR11132.1 ACR14749.1 ACR14749.1 cysQ_1 cysQ_1 hemB hemB ACR13924.1 ACR13924.1 hemG hemG cysM cysM cysD_1 cysD_1 cysN_1 cysN_1 nifP nifP ACR11910.1 ACR11910.1 ACR11182.1 ACR11182.1 hemN hemN cysG cysG ACR14574.1 ACR14574.1 ACR12855.1 ACR12855.1 ACR12426.1 ACR12426.1 ACR13217.1 ACR13217.1 ACR12322.1 ACR12322.1 cobO cobO cobA cobA ACR13457.1 ACR13457.1 hemL hemL cobC cobC cobD cobD ACR14263.1 ACR14263.1 ACR14714.1 ACR14714.1 cobN cobN ACR14612.1 ACR14612.1 hemE hemE cobQ cobQ cobPU cobPU cobT cobT ACR12170.1 ACR12170.1 cobS cobS ACR14465.1 ACR14465.1 hemA hemA ACR13547.1 ACR13547.1 ACR12654.1 ACR12654.1 cysK cysK cysN_2 cysN_2 cysD_2 cysD_2 cysQ_2 cysQ_2 hemH hemH ACR11754.1 ACR11754.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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hemFHemF/Oxygen-dependent Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. (307 aa)
hemCHydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (324 aa)
hemDuroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (266 aa)
ACR11481.1Putative membrane protein; Identified by match to protein family HMM PF04375. (421 aa)
ACR11132.1Metal dependent phosphohydrolase; Identified by match to protein family HMM PF07219. (401 aa)
ACR14749.1Oxidoreductase, short chain dehydrogenase/reductase family; Identified by match to protein family HMM PF00106; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (233 aa)
cysQ_13'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (274 aa)
hemBPorphobilinogen synthase; Identified by match to protein family HMM PF00490; Belongs to the ALAD family. (331 aa)
ACR13924.1Serine acetyltransferase; Identified by match to protein family HMM PF06426; match to protein family HMM TIGR01172. (269 aa)
hemGHemG/oxygen-independent protoporphyrinogen oxidase. (186 aa)
cysMCysteine synthase B; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01138; Belongs to the cysteine synthase/cystathionine beta- synthase family. (296 aa)
cysD_1Sulfate adenylyltransferase, small subunit; Identified by match to protein family HMM PF01507; match to protein family HMM TIGR02039. (308 aa)
cysN_1Sulfate adenylyltransferase, large subunit; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (468 aa)
nifPSerine acetyltransferase NifP; Identified by match to protein family HMM PF00132; match to protein family HMM TIGR01172. (273 aa)
ACR11910.1Conserved hypothetical protein. (111 aa)
ACR11182.1Adenylylsulfate reductase, thioredoxin dependent; Reduction of activated sulfate into sulfite. (236 aa)
hemNOxygen-independent coproporphyrinogen III oxidase; Identified by match to protein family HMM PF04055; match to protein family HMM PF06969; match to protein family HMM TIGR00538; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (471 aa)
cysGSiroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. (459 aa)
ACR14574.1Methyltransferase, FkbM family; Identified by match to protein family HMM TIGR01444. (309 aa)
ACR12855.1Conserved hypothetical protein; Identified by match to protein family HMM PF06073. (164 aa)
ACR12426.1Sulfite reductase; Identified by match to protein family HMM PF01077; match to protein family HMM PF03460. (554 aa)
ACR13217.1Hemin import ATP-binding protein HmuV; Identified by match to protein family HMM PF00005. (268 aa)
ACR12322.1HmuU protein; ABC transporter similarity; identified by match to protein family HMM PF01032; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (344 aa)
cobOcob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (200 aa)
cobAuroporphyrinogen-III C-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01469. (265 aa)
ACR13457.1Putative membrane protein; Identified by match to protein family HMM PF03653; match to protein family HMM TIGR00701. (141 aa)
hemLGlutamate-1-semialdehyde-2,1-aminomutase; Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00713. (427 aa)
cobCThreonine-phosphate decarboxylase; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01140. (339 aa)
cobDCobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (314 aa)
ACR14263.1Conserved hypothetical protein. (81 aa)
ACR14714.1Transporter, MotA/TolQ/ExbB proton channel family; Identified by match to protein family HMM PF01618. (147 aa)
cobNCobN/magnesium chelatase; Identified by match to protein family HMM PF02514. (1483 aa)
ACR14612.1Conserved hypothetical protein; Identified by match to protein family HMM PF00581. (277 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (354 aa)
cobQCobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (486 aa)
cobPUBifunctional adenosylcobalamin biosynthesis protein CobP; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (166 aa)
cobTNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (354 aa)
ACR12170.1Acid phosphatase superfamily member; identified by match to protein family HMM PF00300. (210 aa)
cobSCobalamin-5-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (256 aa)
ACR14465.1Fe3+-hydroxamate ABC transporter periplasmic binding protein; Identified by match to protein family HMM PF01497. (310 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (415 aa)
ACR13547.1Cysteine synthase; Identified by match to protein family HMM PF00291. (306 aa)
ACR12654.1Putative serine O-acetyltransferase; Identified by match to protein family HMM PF00132. (338 aa)
cysKCysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139. (348 aa)
cysN_2Sulfate adenylyltransferase, large subunit; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (632 aa)
cysD_2Sulfate adenylyltransferase, small subunit; Identified by match to protein family HMM PF01507; match to protein family HMM TIGR02039. (304 aa)
cysQ_23'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (273 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (366 aa)
ACR11754.1Rhodanese domain protein; Identified by match to protein family HMM PF00581. (281 aa)
Your Current Organism:
Teredinibacter turnerae T7901
NCBI taxonomy Id: 377629
Other names: T. turnerae T7901, Teredinibacter turnerae str. T7901, Teredinibacter turnerae strain T7901
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