(26 nodes) Mixed, incl. Ubiquinone biosynthesis, and Squalene epoxidase network (Teredinibacter turnerae T7901)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	ubiD	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. (486 aa)
	ACR12853.1	5-formyltetrahydrofolate cyclo-ligase; Identified by match to protein family HMM PF01812; match to protein family HMM TIGR02727; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (185 aa)
	ACR13318.1	ZapA domain containing protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. (95 aa)
	ACR13462.1	Conserved hypothetical protein; Identified by match to protein family HMM TIGR02449. (67 aa)
	ACR10982.1	Identified by match to protein family HMM PF03695; match to protein family HMM TIGR02292; Belongs to the UPF0149 family. (201 aa)
	pepP	Xaa-Pro aminopeptidase; Identified by similarity to SP:P15034; match to protein family HMM PF00557; match to protein family HMM PF05195; Belongs to the peptidase M24B family. (443 aa)
	ubiH	2-polyprenyl-6-methoxyphenol 4-hydroxylase; Identified by match to protein family HMM PF01494; match to protein family HMM TIGR01984; match to protein family HMM TIGR01988. (427 aa)
	ubiF	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Identified by match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM TIGR01988. (419 aa)
	ACR14762.1	Identified by match to protein family HMM PF04403; match to protein family HMM TIGR00155. (425 aa)
	ACR14186.1	Identified by match to protein family HMM PF02470. (536 aa)
	ACR13633.1	Putative lipoprotein; Identified by match to protein family HMM PF03886. (207 aa)
	ACR13043.1	Putative lipoprotein. (178 aa)
	ACR12441.1	Sel1 domain containing protein; Identified by match to protein family HMM PF08238; match to protein family HMM TIGR01352. (470 aa)
	ubiX	Aromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (209 aa)
	ubiG	3-demethylubiquinone-9 3-O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. (257 aa)
	ACR12354.1	Ubiquinone biosynthesis protein Coenzyme Q7 Coq7 family protein; Belongs to the COQ7 family. (169 aa)
	coq7	Ubiquinone biosynthesis protein Coenzyme Q7 Coq7 family protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis. (213 aa)
	ubiE-2	SAM-dependent methyltransferase, UbiE family; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (275 aa)
	ACR12135.1	Sporulation and cell division repeat domain containing protein; Identified by match to protein family HMM PF05036. (194 aa)
	ACR11406.1	DnaJ domain protein; Identified by match to protein family HMM PF06155. (126 aa)
	ubiE	Ubiquinone/menaquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (249 aa)
	ACR14640.1	Conserved hypothetical protein. (212 aa)
	ubiB	2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily. (545 aa)
	ACR13824.1	Outer membrane protein, OMP85 family; Identified by match to protein family HMM PF01103. (564 aa)
	ACR11657.1	Conserved hypothetical protein; Identified by match to protein family HMM PF04357. (1197 aa)
	ubiA	4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. (296 aa)

Your Current Organism:

Teredinibacter turnerae T7901

NCBI taxonomy Id: 377629
Other names: T. turnerae T7901, Teredinibacter turnerae str. T7901, Teredinibacter turnerae strain T7901

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACR10982.1	ACR12441.1	TERTU_0401	TERTU_0409	Identified by match to protein family HMM PF03695; match to protein family HMM TIGR02292; Belongs to the UPF0149 family.	Sel1 domain containing protein; Identified by match to protein family HMM PF08238; match to protein family HMM TIGR01352.	0.417
ACR10982.1	ACR13043.1	TERTU_0401	TERTU_0408	Identified by match to protein family HMM PF03695; match to protein family HMM TIGR02292; Belongs to the UPF0149 family.	Putative lipoprotein.	0.417
ACR10982.1	ACR13318.1	TERTU_0401	TERTU_0398	Identified by match to protein family HMM PF03695; match to protein family HMM TIGR02292; Belongs to the UPF0149 family.	ZapA domain containing protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.	0.633
ACR10982.1	ACR13462.1	TERTU_0401	TERTU_0399	Identified by match to protein family HMM PF03695; match to protein family HMM TIGR02292; Belongs to the UPF0149 family.	Conserved hypothetical protein; Identified by match to protein family HMM TIGR02449.	0.557
ACR10982.1	ACR13633.1	TERTU_0401	TERTU_0407	Identified by match to protein family HMM PF03695; match to protein family HMM TIGR02292; Belongs to the UPF0149 family.	Putative lipoprotein; Identified by match to protein family HMM PF03886.	0.417
ACR10982.1	ACR14186.1	TERTU_0401	TERTU_0406	Identified by match to protein family HMM PF03695; match to protein family HMM TIGR02292; Belongs to the UPF0149 family.	Identified by match to protein family HMM PF02470.	0.417
ACR10982.1	ACR14762.1	TERTU_0401	TERTU_0405	Identified by match to protein family HMM PF03695; match to protein family HMM TIGR02292; Belongs to the UPF0149 family.	Identified by match to protein family HMM PF04403; match to protein family HMM TIGR00155.	0.417
ACR10982.1	pepP	TERTU_0401	TERTU_0402	Identified by match to protein family HMM PF03695; match to protein family HMM TIGR02292; Belongs to the UPF0149 family.	Xaa-Pro aminopeptidase; Identified by similarity to SP:P15034; match to protein family HMM PF00557; match to protein family HMM PF05195; Belongs to the peptidase M24B family.	0.853
ACR10982.1	ubiF	TERTU_0401	TERTU_0404	Identified by match to protein family HMM PF03695; match to protein family HMM TIGR02292; Belongs to the UPF0149 family.	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Identified by match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM TIGR01988.	0.637
ACR10982.1	ubiH	TERTU_0401	TERTU_0403	Identified by match to protein family HMM PF03695; match to protein family HMM TIGR02292; Belongs to the UPF0149 family.	2-polyprenyl-6-methoxyphenol 4-hydroxylase; Identified by match to protein family HMM PF01494; match to protein family HMM TIGR01984; match to protein family HMM TIGR01988.	0.647
ACR11406.1	ACR12135.1	TERTU_3594	TERTU_3590	DnaJ domain protein; Identified by match to protein family HMM PF06155.	Sporulation and cell division repeat domain containing protein; Identified by match to protein family HMM PF05036.	0.520
ACR11406.1	ACR14640.1	TERTU_3594	TERTU_3596	DnaJ domain protein; Identified by match to protein family HMM PF06155.	Conserved hypothetical protein.	0.575
ACR11406.1	ubiB	TERTU_3594	TERTU_3597	DnaJ domain protein; Identified by match to protein family HMM PF06155.	2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily.	0.565
ACR11406.1	ubiE	TERTU_3594	TERTU_3595	DnaJ domain protein; Identified by match to protein family HMM PF06155.	Ubiquinone/menaquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).	0.574
ACR11657.1	ACR12441.1	TERTU_3599	TERTU_0409	Conserved hypothetical protein; Identified by match to protein family HMM PF04357.	Sel1 domain containing protein; Identified by match to protein family HMM PF08238; match to protein family HMM TIGR01352.	0.517
ACR11657.1	ACR13824.1	TERTU_3599	TERTU_3598	Conserved hypothetical protein; Identified by match to protein family HMM PF04357.	Outer membrane protein, OMP85 family; Identified by match to protein family HMM PF01103.	0.996
ACR11657.1	ACR14640.1	TERTU_3599	TERTU_3596	Conserved hypothetical protein; Identified by match to protein family HMM PF04357.	Conserved hypothetical protein.	0.516
ACR11657.1	ubiB	TERTU_3599	TERTU_3597	Conserved hypothetical protein; Identified by match to protein family HMM PF04357.	2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily.	0.574
ACR11657.1	ubiE	TERTU_3599	TERTU_3595	Conserved hypothetical protein; Identified by match to protein family HMM PF04357.	Ubiquinone/menaquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).	0.516
ACR12135.1	ACR11406.1	TERTU_3590	TERTU_3594	Sporulation and cell division repeat domain containing protein; Identified by match to protein family HMM PF05036.	DnaJ domain protein; Identified by match to protein family HMM PF06155.	0.520