STRINGSTRING
pncA pncA KRH_00950 KRH_00950 pdx2 pdx2 nadE nadE purQ purQ KRH_04270 KRH_04270 KRH_04810 KRH_04810 mshB mshB KRH_08230 KRH_08230 dapE dapE KRH_10940 KRH_10940 def def KRH_13680 KRH_13680 KRH_13870 KRH_13870 def-2 def-2 pyrG pyrG hisH hisH purU purU glsA glsA KRH_19510 KRH_19510 purU-2 purU-2 ureC ureC ureB ureB ureA ureA KRH_23000 KRH_23000 KRH_23490 KRH_23490
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pncAPyrazinamidase/nicotinamidase; Bifunctional protein. (205 aa)
KRH_00950Hypothetical protein. (246 aa)
pdx2Pyridoxal phosphate synthase component Pdx2; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (228 aa)
nadENH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (275 aa)
purQPhosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (236 aa)
KRH_04270Hypothetical protein. (333 aa)
KRH_04810Putative acetoin utilization protein. (403 aa)
mshBN-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha- D-glucopyranoside deacetylase MshB. (277 aa)
KRH_08230Hypothetical membrane protein. (217 aa)
dapESuccinyl-diaminopimelate desuccinylase. (368 aa)
KRH_10940Putative penicillin amidase; Protein synonym:penicillin acylase. (949 aa)
defPeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (249 aa)
KRH_13680Hypothetical protein. (243 aa)
KRH_13870Putative PafA-homolog. (575 aa)
def-2Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (189 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (565 aa)
hisHImidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (244 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (290 aa)
glsAGlutaminase; Belongs to the glutaminase family. (613 aa)
KRH_19510Amidase; Belongs to the amidase family. (518 aa)
purU-2Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (302 aa)
ureCUrease alpha subunit; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family. (571 aa)
ureBUrease beta subunit; Belongs to the urease beta subunit family. (131 aa)
ureAUrease gamma subunit; Belongs to the urease gamma subunit family. (100 aa)
KRH_23000Acetamidase. (418 aa)
KRH_23490Putative N-acetylmuramoyl-L-alanine amidase. (411 aa)
Your Current Organism:
Kocuria rhizophila
NCBI taxonomy Id: 378753
Other names: K. rhizophila DC2201, Kocuria rhizophila ATCC 9341, Kocuria rhizophila DC2201, Kocuria rhizophila DSM 348, Kocuria rhizophila NBRC 103217, Kocuria rhizophila str. DC2201, Kocuria rhizophila strain DC2201, Micrococcus luteus ATCC 9341
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.