node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KRH_05140 | cdd | KRH_05140 | KRH_17860 | Hypothetical protein. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.900 |
KRH_11700 | guaD | KRH_11700 | KRH_21400 | Riboflavin synthase alpha chain/3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | Guanine deaminase. | 0.414 |
KRH_11700 | hisI | KRH_11700 | KRH_11760 | Riboflavin synthase alpha chain/3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.585 |
KRH_11700 | ribA | KRH_11700 | KRH_11710 | Riboflavin synthase alpha chain/3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.999 |
KRH_11700 | ribG | KRH_11700 | KRH_11690 | Riboflavin synthase alpha chain/3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | Bifunctional protein; protein synonym:riboflavin biosynthesis protein RibG. | 0.999 |
KRH_11700 | tadA | KRH_11700 | KRH_03170 | Riboflavin synthase alpha chain/3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | Putative tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.414 |
add | cdd | KRH_17840 | KRH_17860 | Protein synonym:adenosine aminohydrolase. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.807 |
add | guaD | KRH_17840 | KRH_21400 | Protein synonym:adenosine aminohydrolase. | Guanine deaminase. | 0.504 |
add | tadA | KRH_17840 | KRH_03170 | Protein synonym:adenosine aminohydrolase. | Putative tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.430 |
cdd | KRH_05140 | KRH_17860 | KRH_05140 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Hypothetical protein. | 0.900 |
cdd | add | KRH_17860 | KRH_17840 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Protein synonym:adenosine aminohydrolase. | 0.807 |
folD | purH | KRH_17990 | KRH_18030 | Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Bifunctional protein. | 0.974 |
folD | ribG | KRH_17990 | KRH_11690 | Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Bifunctional protein; protein synonym:riboflavin biosynthesis protein RibG. | 0.433 |
folE | ribA | KRH_19270 | KRH_11710 | GTP cyclohydrolase I. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.919 |
folE | ribG | KRH_19270 | KRH_11690 | GTP cyclohydrolase I. | Bifunctional protein; protein synonym:riboflavin biosynthesis protein RibG. | 0.572 |
guaD | KRH_11700 | KRH_21400 | KRH_11700 | Guanine deaminase. | Riboflavin synthase alpha chain/3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | 0.414 |
guaD | add | KRH_21400 | KRH_17840 | Guanine deaminase. | Protein synonym:adenosine aminohydrolase. | 0.504 |
hisI | KRH_11700 | KRH_11760 | KRH_11700 | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | Riboflavin synthase alpha chain/3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | 0.585 |
purH | folD | KRH_18030 | KRH_17990 | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Bifunctional protein. | Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.974 |
ribA | KRH_11700 | KRH_11710 | KRH_11700 | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | Riboflavin synthase alpha chain/3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | 0.999 |