STRINGSTRING
GAU_0711 GAU_0711 GAU_0725 GAU_0725 GAU_1577 GAU_1577 prfB prfB lysS lysS lolC lolC lolD lolD GAU_1582 GAU_1582 GAU_1583 GAU_1583 clpC clpC GAU_1585 GAU_1585 GAU_1586 GAU_1586 lpxD lpxD lpxC/fabZ lpxC/fabZ lpxA lpxA GAU_1590 GAU_1590 lpxB lpxB GAU_1592 GAU_1592 lpxK lpxK rlmH rlmH murJ murJ GAU_1618 GAU_1618 GAU_1619 GAU_1619 GAU_1620 GAU_1620 kdsD kdsD kdsC kdsC kdsA kdsA kdsB kdsB GAU_2095 GAU_2095 GAU_2572 GAU_2572 GAU_2573 GAU_2573 GAU_2574 GAU_2574 GAU_2575 GAU_2575 GAU_3853 GAU_3853 GAU_3854 GAU_3854 GAU_3855 GAU_3855 GAU_3856 GAU_3856
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GAU_0711Putative ABC transporter ATP-binding protein. (285 aa)
GAU_0725Putative glycosyltransferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (436 aa)
GAU_1577Hypothetical protein. (101 aa)
prfBPeptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (335 aa)
lysSlysyl-tRNA synthetase; Protein synonym: LysRS; protein synonym: lysine--tRNA ligase; Belongs to the class-II aminoacyl-tRNA synthetase family. (523 aa)
lolCLipoprotein releasing system transmembrane protein LolC. (416 aa)
lolDLipoprotein releasing system ATP-binding protein LolD; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. (250 aa)
GAU_1582Hypothetical protein. (161 aa)
GAU_1583Hypothetical protein. (366 aa)
clpCATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family. (835 aa)
GAU_1585Bacterial surface antigen (D15) family protein. (817 aa)
GAU_1586Outer membrane chaperone Skp (OmpH) family protein. (205 aa)
lpxDUDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (360 aa)
lpxC/fabZ3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily. (424 aa)
lpxAacyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (262 aa)
GAU_1590Putative oxidoreductase. (350 aa)
lpxBlipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (375 aa)
GAU_1592Hypothetical protein. (244 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (358 aa)
rlmHHypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (154 aa)
murJHypothetical protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (524 aa)
GAU_1618Putative ABC transporter ATP-binding protein. (280 aa)
GAU_1619Hypothetical protein. (593 aa)
GAU_1620Hypothetical protein. (204 aa)
kdsDArabinose 5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. (323 aa)
kdsC3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Protein synonym: KDO 8-P phosphatase. (211 aa)
kdsA2-dehydro-3-deoxyphosphooctonate aldolase; Protein synonym: 3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase; protein synonym: KDO 8-P synthase; protein synonym: KDO-8-phosphate synthetase; protein synonym: KDOPS; protein synonym: phospho-2-dehydro-3-deoxyoctonate aldolase; Belongs to the KdsA family. (278 aa)
kdsB3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (258 aa)
GAU_2095Putative lipid A biosynthesis acyltransferase. (312 aa)
GAU_2572Hypothetical protein. (578 aa)
GAU_2573Hypothetical protein. (362 aa)
GAU_2574Putative transporter. (264 aa)
GAU_2575Putative transporter. (295 aa)
GAU_3853ArsR family transcriptional regulator. (310 aa)
GAU_3854Hypothetical membrane protein. (441 aa)
GAU_3855Putative transporter. (275 aa)
GAU_3856Putative transporter. (337 aa)
Your Current Organism:
Gemmatimonas aurantiaca
NCBI taxonomy Id: 379066
Other names: G. aurantiaca T-27, Gemmatimonas aurantiaca DSM 14586, Gemmatimonas aurantiaca JCM 11422, Gemmatimonas aurantiaca NBRC 100505, Gemmatimonas aurantiaca T-27, Gemmatimonas aurantiaca str. T-27, Gemmatimonas aurantiaca strain T-27
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