STRINGSTRING
GAU_0976 GAU_0976 dnaN dnaN polA polA GAU_0072 GAU_0072 GAU_0077 GAU_0077 hsdR hsdR GAU_0089 GAU_0089 GAU_0177 GAU_0177 hsdR-2 hsdR-2 rnhA rnhA GAU_0546 GAU_0546 ruvC ruvC GAU_0646 GAU_0646 GAU_0654 GAU_0654 GAU_0666 GAU_0666 GAU_0695 GAU_0695 dnaE dnaE GAU_0774 GAU_0774 uvrA uvrA GAU_0944 GAU_0944 GAU_1080 GAU_1080 GAU_1121 GAU_1121 GAU_1189 GAU_1189 GAU_1192 GAU_1192 GAU_1485 GAU_1485 GAU_1562 GAU_1562 rph rph uvrC uvrC GAU_1690 GAU_1690 cafA cafA ybeY ybeY GAU_1855 GAU_1855 xseB xseB xseA xseA rny rny dnaQ dnaQ recJ recJ mutS2 mutS2 GAU_1918 GAU_1918 uvrB uvrB GAU_1990 GAU_1990 vapC vapC nfo nfo GAU_2167 GAU_2167 uvrA-2 uvrA-2 GAU_2200 GAU_2200 GAU_2249 GAU_2249 rnhB rnhB GAU_2435 GAU_2435 GAU_2562 GAU_2562 rnz rnz dnaE2 dnaE2 GAU_2795 GAU_2795 GAU_3018 GAU_3018 GAU_3071 GAU_3071 recB recB recC recC GAU_3246 GAU_3246 GAU_3289 GAU_3289 GAU_3331 GAU_3331 GAU_3336 GAU_3336 exoA exoA GAU_3401 GAU_3401 GAU_3404 GAU_3404 GAU_3573 GAU_3573 uvrA-3 uvrA-3 GAU_3688 GAU_3688 GAU_3716 GAU_3716 GAU_3841 GAU_3841 GAU_3872 GAU_3872 GAU_3922 GAU_3922 rnpA rnpA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GAU_0976Hypothetical protein. (371 aa)
dnaNDNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (370 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (984 aa)
GAU_0072Hypothetical protein. (112 aa)
GAU_0077Hypothetical protein. (115 aa)
hsdRType I restriction-modification system restriction subunit; Subunit R is required for both nuclease and ATPase activities, but not for modification. (1023 aa)
GAU_0089Hypothetical protein. (371 aa)
GAU_0177Putative restriction endonuclease. (326 aa)
hsdR-2Type I restriction-modification system restriction subunit; Subunit R is required for both nuclease and ATPase activities, but not for modification. (1049 aa)
rnhARibonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (211 aa)
GAU_0546Hypothetical membrane protein. (465 aa)
ruvCHolliday junction endonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (181 aa)
GAU_0646Hypothetical protein. (195 aa)
GAU_0654Hypothetical protein. (728 aa)
GAU_0666Putative Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (168 aa)
GAU_0695Hypothetical protein. (322 aa)
dnaEDNA polymerase III alpha subunit. (1165 aa)
GAU_0774Exonuclease. (397 aa)
uvrAUvrABC system protein A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (962 aa)
GAU_0944Hypothetical protein. (162 aa)
GAU_1080Hypothetical protein. (316 aa)
GAU_1121Hypothetical protein. (329 aa)
GAU_1189Hypothetical protein. (549 aa)
GAU_1192Hypothetical protein. (252 aa)
GAU_1485Hypothetical protein. (171 aa)
GAU_1562Putative DNase. (276 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (247 aa)
uvrCUvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (616 aa)
GAU_1690Hypothetical protein. (290 aa)
cafAProtein synonym: RNase G. (520 aa)
ybeYHypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (167 aa)
GAU_1855Hypothetical protein. (323 aa)
xseBExodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (70 aa)
xseAExodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (396 aa)
rnyHypothetical protein; Endoribonuclease that initiates mRNA decay. (528 aa)
dnaQDNA polymerase III epsilon subunit. (214 aa)
recJsingle-stranded-DNA-specific exonuclease. (599 aa)
mutS2DNA mismatch repair protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (819 aa)
GAU_1918Hypothetical protein; Belongs to the UPF0102 family. (121 aa)
uvrBUvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...] (700 aa)
GAU_1990Hypothetical protein. (299 aa)
vapCHypothetical protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (130 aa)
nfoEndonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (293 aa)
GAU_2167Putative phosphatase. (362 aa)
uvrA-2UvrABC system protein A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (958 aa)
GAU_2200Endonuclease. (285 aa)
GAU_2249Phage terminase GpA family protein. (683 aa)
rnhBRibonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (228 aa)
GAU_2435Putative exonuclease. (366 aa)
GAU_2562Exonuclease. (323 aa)
rnzRibonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (314 aa)
dnaE2Error-prone DNA polymerase; Belongs to the DNA polymerase type-C family. DnaE2 subfamily. (1113 aa)
GAU_2795Hypothetical protein. (177 aa)
GAU_3018Putative ribonuclease. (388 aa)
GAU_3071Putative endonuclease IV; Protein synonym: endodeoxyribonuclease IV. (299 aa)
recBExodeoxyribonuclease V beta subunit. (1210 aa)
recCExodeoxyribonuclease V gamma subunit. (1101 aa)
GAU_3246Hypothetical protein. (1078 aa)
GAU_3289Hypothetical protein. (908 aa)
GAU_3331Hypothetical protein. (274 aa)
GAU_3336Hypothetical protein. (794 aa)
exoAExodeoxyribonuclease III. (265 aa)
GAU_3401Hypothetical protein. (222 aa)
GAU_3404Hypothetical protein. (358 aa)
GAU_3573Hypothetical protein. (403 aa)
uvrA-3UvrABC system protein A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (955 aa)
GAU_3688Hypothetical protein. (408 aa)
GAU_3716Hypothetical protein. (283 aa)
GAU_3841Putative exonuclease. (363 aa)
GAU_3872Hypothetical protein. (163 aa)
GAU_3922Hypothetical protein. (465 aa)
rnpARibonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (106 aa)
Your Current Organism:
Gemmatimonas aurantiaca
NCBI taxonomy Id: 379066
Other names: G. aurantiaca T-27, Gemmatimonas aurantiaca DSM 14586, Gemmatimonas aurantiaca JCM 11422, Gemmatimonas aurantiaca NBRC 100505, Gemmatimonas aurantiaca T-27, Gemmatimonas aurantiaca str. T-27, Gemmatimonas aurantiaca strain T-27
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