STRINGSTRING
mfd mfd hsdR hsdR hsdR-2 hsdR-2 GAU_0188 GAU_0188 priA priA recQ recQ recG recG recQ-2 recQ-2 uvrB uvrB secA secA GAU_2235 GAU_2235 GAU_2721 GAU_2721 rhlE rhlE GAU_3402 GAU_3402 GAU_3572 GAU_3572 deaD deaD rhlE-2 rhlE-2 hrpB hrpB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
mfdTranscription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1104 aa)
hsdRType I restriction-modification system restriction subunit; Subunit R is required for both nuclease and ATPase activities, but not for modification. (1023 aa)
hsdR-2Type I restriction-modification system restriction subunit; Subunit R is required for both nuclease and ATPase activities, but not for modification. (1049 aa)
GAU_0188Helicase. (1150 aa)
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (767 aa)
recQATP-dependent DNA helicase RecQ. (524 aa)
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (706 aa)
recQ-2ATP-dependent DNA helicase RecQ. (598 aa)
uvrBUvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...] (700 aa)
secAPreprotein translocase SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. (1106 aa)
GAU_2235Hypothetical protein. (588 aa)
GAU_2721Putative helicase. (800 aa)
rhlEATP-dependent RNA helicase RhlE; Belongs to the DEAD box helicase family. (374 aa)
GAU_3402ATP-dependent helicase. (851 aa)
GAU_3572Hypothetical protein. (2009 aa)
deaDATP-dependent DEAD-box RNA helicase DeaD; Protein synonym: cold-shock DEAD-box protein A; Belongs to the DEAD box helicase family. (594 aa)
rhlE-2ATP-dependent RNA helicase RhlE; Belongs to the DEAD box helicase family. (498 aa)
hrpBATP-dependent helicase. (849 aa)
Your Current Organism:
Gemmatimonas aurantiaca
NCBI taxonomy Id: 379066
Other names: G. aurantiaca T-27, Gemmatimonas aurantiaca DSM 14586, Gemmatimonas aurantiaca JCM 11422, Gemmatimonas aurantiaca NBRC 100505, Gemmatimonas aurantiaca T-27, Gemmatimonas aurantiaca str. T-27, Gemmatimonas aurantiaca strain T-27
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