STRINGSTRING
lpd lpd GAU_0745 GAU_0745 pdhC pdhC pdhB pdhB pdhA pdhA adh adh pykA pykA pgi pgi GAU_1107 GAU_1107 eno eno fbp fbp manB manB tpiA tpiA pgk pgk gapA gapA GAU_2061 GAU_2061 glk glk pckA pckA GAU_2381 GAU_2381 GAU_2382 GAU_2382 gpm gpm acs acs adh-2 adh-2 pfkA pfkA GAU_2900 GAU_2900 pgm pgm GAU_3007 GAU_3007 adh-3 adh-3 GAU_3382 GAU_3382
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
lpdProtein synonym: dihydrolipoyl dehydrogenase. (470 aa)
GAU_0745Protein synonym: dihydrolipoyl dehydrogenase. (466 aa)
pdhCPyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (441 aa)
pdhBPyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (326 aa)
pdhAPyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (347 aa)
adhNADP-dependent alcohol dehydrogenase. (356 aa)
pykAPyruvate kinase; Belongs to the pyruvate kinase family. (466 aa)
pgiGlucose-6-phosphate isomerase; Protein synonym: GPI; protein synonym: PGI; protein synonym: PHI; protein synonym: phosphoglucose isomerase; protein synonym: phosphohexose isomerase; Belongs to the GPI family. (462 aa)
GAU_1107Putative fructose-bisphosphate aldolase; Protein synonym: fructose-1,6-bisphosphate triosephosphate-lyase; protein synonym: ketose 1-phosphate aldolase. (484 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (426 aa)
fbpFructose-1,6-bisphosphatase; Protein synonym: D-fructose-1,6-bisphosphate 1-phosphohydrolase. (360 aa)
manBPhosphomannomutase; Protein synonym: PMM. (459 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (398 aa)
gapAGlyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (337 aa)
GAU_2061Putative aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (809 aa)
glkGlucokinase; Protein synonym: glucose kinase. (331 aa)
pckAATP-dependent phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (539 aa)
GAU_2381Putative 2-oxoglutarate ferredoxin-oxidoreductase alpha subunit. (612 aa)
GAU_2382Putative 2-oxoglutarate ferredoxin-oxidoreductase beta subunit. (351 aa)
gpm2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (520 aa)
acsAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (654 aa)
adh-2Alcohol dehydrogenase. (341 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (359 aa)
GAU_2900Alcohol dehydrogenase. (377 aa)
pgmPhosphoglucomutase; Protein synonym: glucose phosphomutase. (541 aa)
GAU_3007Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (517 aa)
adh-3NADP-dependent alcohol dehydrogenase. (353 aa)
GAU_3382Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (510 aa)
Your Current Organism:
Gemmatimonas aurantiaca
NCBI taxonomy Id: 379066
Other names: G. aurantiaca T-27, Gemmatimonas aurantiaca DSM 14586, Gemmatimonas aurantiaca JCM 11422, Gemmatimonas aurantiaca NBRC 100505, Gemmatimonas aurantiaca T-27, Gemmatimonas aurantiaca str. T-27, Gemmatimonas aurantiaca strain T-27
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.