(72 nodes) CheY-like superfamily network (Vibrio sinaloensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cheB-2	Chemotaxis protein CheY; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (373 aa)
	KIE22530.1	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology. (235 aa)
	KIE22710.1	Phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (515 aa)
	KIE22642.1	Chemotaxis protein CheV; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa)
	KIE22656.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (875 aa)
	KIE22696.1	Chemotaxis protein CheC; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
	KIE22231.1	Transcriptional regulator PhoB; Two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB; Derived by automated computational analysis using gene prediction method: Protein Homology. (229 aa)
	KIE22267.1	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa)
	KIE22421.1	Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (468 aa)
	KIE21257.1	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
	KIE21285.1	Chemotaxis protein CheW; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
	KIE21328.1	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology. (323 aa)
	KIE21358.1	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology. (689 aa)
	KIE21405.1	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology. (957 aa)
	KIE22116.1	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa)
	KIE21429.1	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa)
	KIE21469.1	Nitrate/nitrite response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
	KIE21495.1	ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (850 aa)
	KIE21527.1	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology. (234 aa)
	dpiA	Two-component response regulator DpiA; Regulates the expression of citrate fermentation genes; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
	KIE21569.1	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology. (420 aa)
	KIE21638.1	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)
	KIE22132.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (126 aa)
	KIE21650.1	Two-component hybrid sensor and regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (1594 aa)
	KIE21651.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (401 aa)
	KIE21928.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (681 aa)
	KIE21964.1	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology. (147 aa)
	KIE21965.1	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (580 aa)
	KIE22001.1	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology. (563 aa)
	cheB	Chemotaxis protein; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (349 aa)
	KIE22010.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (119 aa)
	KIE20973.1	Response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa)
	KIE20999.1	Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (444 aa)
	KIE21023.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1128 aa)
	KIE20620.1	Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (481 aa)
	KIE20645.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (774 aa)
	KIE20646.1	LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (489 aa)
	KIE20669.1	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
	KIE20313.1	Histidine kinase; Part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; Derived by automated computational analysis using gene prediction method: Protein Homology. (929 aa)
	KIE20330.1	TorR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
	KIE20363.1	ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (787 aa)
	KIE20445.1	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa)
	KIE20574.1	Chemotaxis protein CheW; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)
	KIE19822.1	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology. (366 aa)
	KIE19831.1	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology. (235 aa)
	KIE19845.1	C4-dicarboxylate ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (452 aa)
	KIE19871.1	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (237 aa)
	KIE19920.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (810 aa)
	KIE20254.1	C4-dicarboxylate ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (448 aa)
	KIE19963.1	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
	KIE19964.1	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology. (1317 aa)
	KIE20056.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (831 aa)
	sirA	Response regulator; In Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; Derived by automated computational analysis using gene prediction method: Protein Homology. (214 aa)
	KIE19623.1	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa)
	KIE19790.1	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa)
	KIE19656.1	LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
	KIE19680.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (566 aa)
	KIE19706.1	Response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (298 aa)
	KIE19751.1	ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (641 aa)
	KIE19752.1	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology. (165 aa)
	KIE19554.1	Response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
	KIE19397.1	LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa)
	KIE19403.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1142 aa)
	ompR	Osmolarity response regulator; Part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa)
	KIE19002.1	ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (464 aa)
	KIE19023.1	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa)
	KIE19055.1	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
	KIE19065.1	C4-dicarboxylate ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (446 aa)
	KIE19134.1	Chemotaxis protein CheW; Derived by automated computational analysis using gene prediction method: Protein Homology. (315 aa)
	KIE18815.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (573 aa)
	KIE18728.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (122 aa)
	glnG	Nitrogen regulation protein NR(I); Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (467 aa)

Your Current Organism:

Vibrio sinaloensis

NCBI taxonomy Id: 379097
Other names: CAIM 797, CECT 7298, V. sinaloensis, Vibrio sinaloensis Gomez-Gil et al. 2008, Vibrio sp. CAIM 695, Vibrio sp. CAIM 797

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KIE18728.1	KIE18815.1	SE23_20910	SE23_20235	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.685
KIE18728.1	KIE19023.1	SE23_20910	SE23_18640	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.510
KIE18728.1	KIE19055.1	SE23_20910	SE23_18820	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.417
KIE18728.1	KIE19134.1	SE23_20910	SE23_19245	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Chemotaxis protein CheW; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.707
KIE18728.1	KIE19403.1	SE23_20910	SE23_16925	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.863
KIE18728.1	KIE19554.1	SE23_20910	SE23_16210	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.597
KIE18728.1	KIE19680.1	SE23_20910	SE23_15515	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.492
KIE18728.1	KIE19751.1	SE23_20910	SE23_15910	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.703
KIE18728.1	KIE19790.1	SE23_20910	SE23_15290	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.540
KIE18728.1	KIE19822.1	SE23_20910	SE23_12765	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.517
KIE18728.1	KIE19831.1	SE23_20910	SE23_12815	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.492
KIE18728.1	KIE19871.1	SE23_20910	SE23_13025	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.644
KIE18728.1	KIE19920.1	SE23_20910	SE23_13300	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.816
KIE18728.1	KIE19963.1	SE23_20910	SE23_13545	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.484
KIE18728.1	KIE19964.1	SE23_20910	SE23_13550	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.995
KIE18728.1	KIE20056.1	SE23_20910	SE23_14040	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.649
KIE18728.1	KIE20313.1	SE23_20910	SE23_11120	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.930
KIE18728.1	KIE20330.1	SE23_20910	SE23_11205	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	TorR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.582
KIE18728.1	KIE20363.1	SE23_20910	SE23_11390	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.974
KIE18728.1	KIE20445.1	SE23_20910	SE23_11815	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.534