(65 nodes) HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain network (Vibrio sinaloensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	KIE20313.1	Histidine kinase; Part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; Derived by automated computational analysis using gene prediction method: Protein Homology. (929 aa)
	KIE21877.1	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (636 aa)
	KIE18984.1	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (623 aa)
	KIE19020.1	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (543 aa)
	KIE19056.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (482 aa)
	KIE18880.1	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (626 aa)
	KIE18846.1	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (663 aa)
	KIE18699.1	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (843 aa)
	KIE19639.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (432 aa)
	KIE20235.1	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (545 aa)
	KIE20192.1	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (652 aa)
	KIE20069.1	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (489 aa)
	KIE20030.1	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (538 aa)
	KIE19972.1	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (705 aa)
	KIE19965.1	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (578 aa)
	KIE19951.1	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (539 aa)
	KIE19842.1	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (678 aa)
	KIE19830.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (535 aa)
	KIE20327.1	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (418 aa)
	KIE21862.1	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (477 aa)
	KIE22152.1	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (654 aa)
	KIE21926.1	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (553 aa)
	KIE22007.1	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (670 aa)
	KIE22158.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (458 aa)
	KIE22063.1	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (569 aa)
	KIE20963.1	Diguanylate phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (782 aa)
	KIE21846.1	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (547 aa)
	KIE21650.1	Two-component hybrid sensor and regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (1594 aa)
	KIE21631.1	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (596 aa)
	KIE21625.1	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (530 aa)
	KIE21618.1	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (452 aa)
	KIE21570.1	ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (786 aa)
	KIE21558.1	Hemolysin; Derived by automated computational analysis using gene prediction method: Protein Homology. (548 aa)
	KIE21531.1	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (666 aa)
	KIE22126.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (447 aa)
	KIE21476.1	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (656 aa)
	KIE22118.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (577 aa)
	KIE21405.1	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology. (957 aa)
	KIE21395.1	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (586 aa)
	KIE21365.1	Diguanylate phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (829 aa)
	KIE22112.1	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (770 aa)
	KIE21299.1	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (545 aa)
	KIE21256.1	ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (428 aa)
	KIE21252.1	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (630 aa)
	KIE21225.1	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (542 aa)
	KIE20312.1	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa)
	KIE20682.1	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (627 aa)
	KIE20645.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (774 aa)
	KIE20631.1	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (676 aa)
	KIE20617.1	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (629 aa)
	KIE21023.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1128 aa)
	KIE22395.1	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (634 aa)
	KIE22369.1	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (498 aa)
	KIE22691.1	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (622 aa)
	KIE22679.1	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (637 aa)
	KIE22564.1	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (578 aa)
	KIE22529.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (478 aa)
	KIE22468.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (649 aa)
	envZ	Osmolarity sensor protein; Membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR; Derived by automated computational analysis using gene prediction method: Protein Homology. (435 aa)
	cpxA	Two-component sensor protein; Part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
	KIE19774.1	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (628 aa)
	KIE19770.1	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (626 aa)
	KIE19693.1	Metal-dependent phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (496 aa)
	KIE19794.1	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (537 aa)
	KIE19649.1	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (544 aa)

Your Current Organism:

Vibrio sinaloensis

NCBI taxonomy Id: 379097
Other names: CAIM 797, CECT 7298, V. sinaloensis, Vibrio sinaloensis Gomez-Gil et al. 2008, Vibrio sp. CAIM 695, Vibrio sp. CAIM 797

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KIE18699.1	KIE18846.1	SE23_20960	SE23_20155	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.579
KIE18699.1	KIE18880.1	SE23_20960	SE23_19885	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.579
KIE18699.1	KIE18984.1	SE23_20960	SE23_18425	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.579
KIE18699.1	KIE19020.1	SE23_20960	SE23_18620	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.579
KIE18699.1	KIE19056.1	SE23_20960	SE23_18825	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.833
KIE18699.1	KIE19639.1	SE23_20960	SE23_15285	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.833
KIE18699.1	KIE19649.1	SE23_20960	SE23_15345	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.579
KIE18699.1	KIE19693.1	SE23_20960	SE23_15585	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Metal-dependent phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.781
KIE18699.1	KIE19770.1	SE23_20960	SE23_16010	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.579
KIE18699.1	KIE19774.1	SE23_20960	SE23_16030	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.579
KIE18699.1	KIE19794.1	SE23_20960	SE23_15555	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.579
KIE18699.1	KIE19830.1	SE23_20960	SE23_12810	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.780
KIE18699.1	KIE19842.1	SE23_20960	SE23_12870	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.579
KIE18699.1	KIE19951.1	SE23_20960	SE23_13470	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.651
KIE18699.1	KIE19965.1	SE23_20960	SE23_13555	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.579
KIE18699.1	KIE19972.1	SE23_20960	SE23_13590	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.579
KIE18699.1	KIE20030.1	SE23_20960	SE23_13890	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.579
KIE18699.1	KIE20069.1	SE23_20960	SE23_14130	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.873
KIE18699.1	KIE20192.1	SE23_20960	SE23_14830	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.579
KIE18699.1	KIE20235.1	SE23_20960	SE23_15050	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Chemotaxis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.579