STRINGSTRING
KIE19852.1 KIE19852.1 sirA sirA KIE19729.1 KIE19729.1 KIE19739.1 KIE19739.1 KIE19581.1 KIE19581.1 cysE cysE KIE19380.1 KIE19380.1 fis fis KIE19428.1 KIE19428.1 KIE19430.1 KIE19430.1 KIE19512.1 KIE19512.1 KIE19513.1 KIE19513.1 KIE19514.1 KIE19514.1 KIE19515.1 KIE19515.1 KIE19516.1 KIE19516.1 KIE19517.1 KIE19517.1 KIE19518.1 KIE19518.1 KIE19519.1 KIE19519.1 KIE19520.1 KIE19520.1 KIE19521.1 KIE19521.1 KIE19522.1 KIE19522.1 KIE19540.1 KIE19540.1 KIE19002.1 KIE19002.1 KIE19003.1 KIE19003.1 KIE19091.1 KIE19091.1 KIE19128.1 KIE19128.1 KIE19157.1 KIE19157.1 KIE19169.1 KIE19169.1 cyaA cyaA KIE18918.1 KIE18918.1 KIE18925.1 KIE18925.1 hfq hfq KIE18797.1 KIE18797.1 fliA fliA KIE18678.1 KIE18678.1 KIE22632.1 KIE22632.1 KIE22419.1 KIE22419.1 KIE22420.1 KIE22420.1 KIE22421.1 KIE22421.1 KIE22110.1 KIE22110.1 KIE21358.1 KIE21358.1 KIE21359.1 KIE21359.1 KIE21365.1 KIE21365.1 KIE22113.1 KIE22113.1 KIE21487.1 KIE21487.1 KIE21495.1 KIE21495.1 KIE21496.1 KIE21496.1 KIE22128.1 KIE22128.1 KIE21607.1 KIE21607.1 KIE21651.1 KIE21651.1 KIE21665.1 KIE21665.1 KIE21744.1 KIE21744.1 KIE21829.1 KIE21829.1 KIE21833.1 KIE21833.1 KIE21838.1 KIE21838.1 KIE21839.1 KIE21839.1 KIE21840.1 KIE21840.1 KIE21841.1 KIE21841.1 KIE22023.1 KIE22023.1 KIE20963.1 KIE20963.1 KIE20999.1 KIE20999.1 KIE21005.1 KIE21005.1 KIE21013.1 KIE21013.1 KIE21056.1 KIE21056.1 KIE21068.1 KIE21068.1 rpoS rpoS luxS luxS csrA csrA KIE20763.1 KIE20763.1 KIE20764.1 KIE20764.1 KIE20765.1 KIE20765.1 KIE20766.1 KIE20766.1 KIE20769.1 KIE20769.1 KIE20646.1 KIE20646.1 KIE20313.1 KIE20313.1 KIE20591.1 KIE20591.1 KIE20448.1 KIE20448.1 KIE20535.1 KIE20535.1 KIE20556.1 KIE20556.1 KIE20557.1 KIE20557.1 KIE19821.1 KIE19821.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KIE19852.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa)
sirAResponse regulator; In Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; Derived by automated computational analysis using gene prediction method: Protein Homology. (214 aa)
KIE19729.1Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (509 aa)
KIE19739.1Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (640 aa)
KIE19581.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (179 aa)
cysECatalyzes the O-acetylation of serine; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa)
KIE19380.1Crp/Fnr family transcriptional regulator; cAMP receptor protein; complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
fisFis family transcriptional regulator; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. (98 aa)
KIE19428.1Sugar transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (377 aa)
KIE19430.1Tyrosine protein kinase; Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide); Derived by automated computational analysis using gene prediction method: Protein Homology. (720 aa)
KIE19512.1General secretion pathway protein GspN; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
KIE19513.1General secretion pathway protein GspM; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. (163 aa)
KIE19514.1General secretion pathway protein GspL; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. (403 aa)
KIE19515.1General secretion pathway protein GspK; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)
KIE19516.1General secretion pathway protein GspJ; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)
KIE19517.1General secretion pathway protein GspI; Derived by automated computational analysis using gene prediction method: Protein Homology. (118 aa)
KIE19518.1General secretion pathway protein GspH; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)
KIE19519.1General secretion pathway protein GspG; Derived by automated computational analysis using gene prediction method: Protein Homology. (147 aa)
KIE19520.1General secretion pathway protein GspF; Derived by automated computational analysis using gene prediction method: Protein Homology. (407 aa)
KIE19521.1General secretion pathway protein GspE; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. (496 aa)
KIE19522.1General secretion pathway protein GspD; Derived by automated computational analysis using gene prediction method: Protein Homology. (678 aa)
KIE19540.1General secretion pathway protein GspC; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
KIE19002.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (464 aa)
KIE19003.1Phosphorelay protein LuxU; Derived by automated computational analysis using gene prediction method: Protein Homology. (113 aa)
KIE19091.1Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (486 aa)
KIE19128.1PTS glucose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology. (476 aa)
KIE19157.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (824 aa)
KIE19169.1Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (669 aa)
cyaAAdenylate cyclase; Catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; Derived by automated computational analysis using gene prediction method: Protein Homology. (842 aa)
KIE18918.1Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (825 aa)
KIE18925.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (412 aa)
hfqRNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. (88 aa)
KIE18797.1RNA polymerase factor sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (486 aa)
fliARNA polymerase sigma 70; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily. (244 aa)
KIE18678.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (75 aa)
KIE22632.1LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)
KIE22419.1Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (488 aa)
KIE22420.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (352 aa)
KIE22421.1Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (468 aa)
KIE22110.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa)
KIE21358.1Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology. (689 aa)
KIE21359.1CAI-1 autoinducer synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (393 aa)
KIE21365.1Diguanylate phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (829 aa)
KIE22113.1Ribose ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (352 aa)
KIE21487.1Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (640 aa)
KIE21495.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (850 aa)
KIE21496.1ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa)
KIE22128.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (649 aa)
KIE21607.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (825 aa)
KIE21651.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (401 aa)
KIE21665.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa)
KIE21744.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (137 aa)
KIE21829.1Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa)
KIE21833.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (177 aa)
KIE21838.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (734 aa)
KIE21839.1Capsular biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (176 aa)
KIE21840.1Capsular polysaccharide synthesis enzyme CpsB; Derived by automated computational analysis using gene prediction method: Protein Homology. (411 aa)
KIE21841.1Capsular biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (471 aa)
KIE22023.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (298 aa)
KIE20963.1Diguanylate phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (782 aa)
KIE20999.1Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (444 aa)
KIE21005.1c-di-GMP phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (683 aa)
KIE21013.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (331 aa)
KIE21056.1LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)
KIE21068.1General secretion pathway protein GspE; Derived by automated computational analysis using gene prediction method: Protein Homology. (562 aa)
rpoSRNA polymerase sigma factor RpoS; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. (331 aa)
luxSS-ribosylhomocysteinase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (172 aa)
csrACarbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). (65 aa)
KIE20763.1MSHA biogenesis protein MshD; Derived by automated computational analysis using gene prediction method: Protein Homology. (183 aa)
KIE20764.1MSHA biogenesis protein MshC; Derived by automated computational analysis using gene prediction method: Protein Homology. (159 aa)
KIE20765.1MSHA biogenesis protein MshA; Derived by automated computational analysis using gene prediction method: Protein Homology. (157 aa)
KIE20766.1MSHA biogenesis protein MshB; Derived by automated computational analysis using gene prediction method: Protein Homology. (191 aa)
KIE20769.1MSHA biogenesis protein MshE; Derived by automated computational analysis using gene prediction method: Protein Homology. (574 aa)
KIE20646.1LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (489 aa)
KIE20313.1Histidine kinase; Part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; Derived by automated computational analysis using gene prediction method: Protein Homology. (929 aa)
KIE20591.1c-di-GMP phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (679 aa)
KIE20448.1Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (507 aa)
KIE20535.1PTS system glucose-specific transporter subunit IIA; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. (169 aa)
KIE20556.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (177 aa)
KIE20557.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (287 aa)
KIE19821.1LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family. (291 aa)
Your Current Organism:
Vibrio sinaloensis
NCBI taxonomy Id: 379097
Other names: CAIM 797, CECT 7298, V. sinaloensis, Vibrio sinaloensis Gomez-Gil et al. 2008, Vibrio sp. CAIM 695, Vibrio sp. CAIM 797
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