STRINGSTRING
KZO57588.1 KZO57588.1 KZO60526.1 KZO60526.1 KZO60502.1 KZO60502.1 lexA lexA recA recA polA polA KZO59888.1 KZO59888.1 KZO59498.1 KZO59498.1 topA topA KZO58627.1 KZO58627.1 KZO58096.1 KZO58096.1 KZO57898.1 KZO57898.1 KZO57908.1 KZO57908.1 dinB dinB KZO57806.1 KZO57806.1 KZO57668.1 KZO57668.1 KZO57669.1 KZO57669.1 dnaE2 dnaE2 KZO57830.1 KZO57830.1 KZO57831.1 KZO57831.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KZO57588.1TraA protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1174 aa)
KZO60526.1DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (595 aa)
KZO60502.1TraA protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1109 aa)
lexARepressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (222 aa)
recADNA recombination/repair protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (367 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (900 aa)
KZO59888.15'-3' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)
KZO59498.1Helicase SNF2; Derived by automated computational analysis using gene prediction method: Protein Homology. (1126 aa)
topADNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (999 aa)
KZO58627.1DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (391 aa)
KZO58096.1ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (889 aa)
KZO57898.1Recombinase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. (725 aa)
KZO57908.1Recombinase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. (551 aa)
dinBDNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (486 aa)
KZO57806.1ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (695 aa)
KZO57668.1ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the helicase family. UvrD subfamily. (1108 aa)
KZO57669.1ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the helicase family. UvrD subfamily. (1093 aa)
dnaE2Error-prone DNA polymerase; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1049 aa)
KZO57830.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (550 aa)
KZO57831.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
Your Current Organism:
Dietzia maris
NCBI taxonomy Id: 37915
Other names: ATCC 35013, AUCNM A-593, AUCNM:A:593, Brevibacterium maris, CCUG 44488, CIP 104188, D. maris, DSM 43672, IEGM 55, IFO 15801, IMV 195, JCM 6166, LMG 5361, LMG:5361, NBRC 15801, NRRL B-16941, NRRL:B:16941, Rhodococcus maris, VKM Ac-593, VKM:Ac:593
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