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AMM30739.1 AMM30739.1 AMM30781.1 AMM30781.1 AMM31027.1 AMM31027.1 AMM31028.1 AMM31028.1 AMM31059.1 AMM31059.1 AMM31175.1 AMM31175.1 AMM31195.1 AMM31195.1 AMM31236.1 AMM31236.1 AMM31273.1 AMM31273.1 AMM31274.1 AMM31274.1 AMM31644.1 AMM31644.1 AMM31646.1 AMM31646.1 AMM31825.1 AMM31825.1 AMM31892.1 AMM31892.1 AMM31983.1 AMM31983.1 AMM32112.1 AMM32112.1 AMM32131.1 AMM32131.1 AMM32211.1 AMM32211.1 AMM32218.1 AMM32218.1 AMM32220.1 AMM32220.1 AMM32281.1 AMM32281.1 AMM32302.1 AMM32302.1 AMM32303.1 AMM32303.1 AMM32304.1 AMM32304.1 AMM32305.1 AMM32305.1 AMM32306.1 AMM32306.1 AMM32394.1 AMM32394.1 AMM32429.1 AMM32429.1 AMM32430.1 AMM32430.1 AMM32431.1 AMM32431.1 AMM32432.1 AMM32432.1 AMM32433.1 AMM32433.1 AMM32434.1 AMM32434.1 AMM32464.1 AMM32464.1 AMM32563.1 AMM32563.1 AMM32564.1 AMM32564.1 AMM32654.1 AMM32654.1 AMM32655.1 AMM32655.1 AMM32669.1 AMM32669.1 AMM32670.1 AMM32670.1 AMM32686.1 AMM32686.1 AMM32688.1 AMM32688.1 AMM32692.1 AMM32692.1 AMM32693.1 AMM32693.1 AMM32862.1 AMM32862.1 AMM32918.1 AMM32918.1 AMM32920.1 AMM32920.1 AMM32921.1 AMM32921.1 AMM32922.1 AMM32922.1 AMM32923.1 AMM32923.1 AMM32925.1 AMM32925.1 AMM32926.1 AMM32926.1 acsA acsA AMM33043.1 AMM33043.1 fabH fabH acpP acpP AMM33046.1 AMM33046.1 AMM33326.1 AMM33326.1 AMM33327.1 AMM33327.1 adc adc AMM33531.1 AMM33531.1 acpS acpS AMM33697.1 AMM33697.1 AMM33743.1 AMM33743.1 AMM33744.1 AMM33744.1 AMM33745.1 AMM33745.1 AMM33746.1 AMM33746.1 AMM33747.1 AMM33747.1 AMM33748.1 AMM33748.1 AMM33750.1 AMM33750.1 AMM33751.1 AMM33751.1 AMM33752.1 AMM33752.1 AMM33753.1 AMM33753.1 AMM33754.1 AMM33754.1 AMM33807.1 AMM33807.1 AMM33844.1 AMM33844.1 ackA ackA AMM33858.1 AMM33858.1 AMM33872.1 AMM33872.1 AMM33884.1 AMM33884.1 AMM33885.1 AMM33885.1 AMM33886.1 AMM33886.1 AMM33930.1 AMM33930.1 AMM33931.1 AMM33931.1 AMM33932.1 AMM33932.1 acsA-2 acsA-2 AMM34044.1 AMM34044.1 AMM34045.1 AMM34045.1 AMM34046.1 AMM34046.1 AMM34050.1 AMM34050.1 AMM34076.1 AMM34076.1 AMM34156.1 AMM34156.1 AMM34215.1 AMM34215.1 AMM34221.1 AMM34221.1 AMM34226.1 AMM34226.1 AMM34234.1 AMM34234.1 AMM34366.1 AMM34366.1 AMM34422.1 AMM34422.1 AMM34423.1 AMM34423.1 AMM34428.1 AMM34428.1 AMM34521.1 AMM34521.1 AMM34637.1 AMM34637.1 AMM34638.1 AMM34638.1 AMM34652.1 AMM34652.1 AMM34666.1 AMM34666.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AMM30739.1Short-chain dehydrogenase; Pfam:pfam13561 Enoyl-(Acyl carrier protein) reductase. (264 aa)
AMM30781.1Acetyl-CoA carboxylase beta subunit; Pfam:pfam01039 Carboxyl transferase domain. (508 aa)
AMM31027.1Pfam:pfam07005 Protein of unknown function, DUF1537. (487 aa)
AMM31028.1Oxidoreductase; Pfam:pfam03446 NAD binding domain of 6-phosphogluconate dehydrogenase. (302 aa)
AMM31059.1Pfam:pfam00106 short chain dehydrogenase. (247 aa)
AMM31175.1Pfam:pfam00441 Acyl-CoA dehydrogenase, C-terminal domain. (393 aa)
AMM31195.1Acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (651 aa)
AMM31236.1Pfam:pfam00441 Acyl-CoA dehydrogenase, C-terminal domain. (378 aa)
AMM31273.1Pfam:pfam00106 short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (258 aa)
AMM31274.1Pfam:pfam00441 Acyl-CoA dehydrogenase, C-terminal domain. (399 aa)
AMM31644.1Acetyl-CoA synthetase (Acetate-CoA ligase); Pfam:pfam00501 AMP-binding enzyme. (551 aa)
AMM31646.1Enoyl-CoA hydratase/carnithine racemase; Pfam:pfam00378 Enoyl-CoA hydratase/isomerase family; Belongs to the enoyl-CoA hydratase/isomerase family. (264 aa)
AMM31825.1Pfam:pfam00171 Aldehyde dehydrogenase family. (499 aa)
AMM31892.13-hydroxyisobutyrate dehydrogenase; Pfam:pfam03446 NAD binding domain of 6-phosphogluconate dehydrogenase. (307 aa)
AMM31983.1Long-chain-fatty-acid-CoA ligase; Pfam:pfam00501 AMP-binding enzyme. (497 aa)
AMM32112.1Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (204 aa)
AMM32131.1Long-chain fatty acid--CoA ligase; Pfam:pfam00501 AMP-binding enzyme. (628 aa)
AMM32211.1acetyl-CoA carboxylase; Pfam:pfam02786 Carbamoyl-phosphate synthase L chain, ATP binding domain. (595 aa)
AMM32218.1methylmalonyl-CoA carboxyltransferase; Pfam:pfam01039 Carboxyl transferase domain. (527 aa)
AMM32220.1biotin-(acetyl-CoA carboxylase) ligase; Pfam:pfam03099 Biotin/lipoate A/B protein ligase family. (296 aa)
AMM32281.1Pfam:pfam00441 Acyl-CoA dehydrogenase, C-terminal domain. (395 aa)
AMM32302.1Acetyl-CoA carboxylase, carboxyltransferase component (Subunits alpha and beta); Pfam:pfam01039 Carboxyl transferase domain. (535 aa)
AMM32303.1Pfam:pfam02786 Carbamoyl-phosphate synthase L chain, ATP binding domain. (708 aa)
AMM32304.1Pfam:pfam00441 Acyl-CoA dehydrogenase, C-terminal domain. (390 aa)
AMM32305.1Pfam:pfam01144 Coenzyme A transferase. (258 aa)
AMM32306.1Pfam:pfam01144 Coenzyme A transferase. (228 aa)
AMM32394.1Pfam:pfam01648 4'-phosphopantetheinyl transferase superfamily; Belongs to the P-Pant transferase superfamily. (224 aa)
AMM32429.1Pfam:pfam00285 Citrate synthase; Belongs to the citrate synthase family. (383 aa)
AMM32430.12-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. (305 aa)
AMM32431.12-methylcitrate dehydratase; Pfam:pfam03972 MmgE/PrpD family. (506 aa)
AMM32432.1Pfam:pfam00392 Bacterial regulatory proteins, gntR family. (213 aa)
AMM32433.1acyl-CoA synthetase; Pfam:pfam00501 AMP-binding enzyme. (636 aa)
AMM32434.1Pfam:pfam13279 Thioesterase-like superfamily. (180 aa)
AMM32464.1Long-chain fatty acid--CoA ligase; Pfam:pfam00501 AMP-binding enzyme. (606 aa)
AMM32563.1Pfam:pfam02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. (715 aa)
AMM32564.1Acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family. (404 aa)
AMM32654.1AMP-dependent synthetase and ligase; Pfam:pfam00501 AMP-binding enzyme. (469 aa)
AMM32655.13-ketoacyl-CoA thiolase Acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family. (404 aa)
AMM32669.13-oxoacyl-(Acyl-carrier-protein) reductase; Pfam:pfam00106 short chain dehydrogenase. (241 aa)
AMM32670.1Dehydrogenase; Pfam:pfam00106 short chain dehydrogenase. (247 aa)
AMM32686.1Pfam:pfam01756 Acyl-CoA oxidase. (691 aa)
AMM32688.1Acetyl-CoA acyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family. (440 aa)
AMM32692.1Pfam:pfam01546 Peptidase family M20/M25/M40. (440 aa)
AMM32693.1Pfam:pfam00441 Acyl-CoA dehydrogenase, C-terminal domain. (386 aa)
AMM32862.1Putative 3-hydroxyisobutyrate dehydrogenase; Pfam:pfam03446 NAD binding domain of 6-phosphogluconate dehydrogenase. (290 aa)
AMM32918.1Pfam:pfam00441 Acyl-CoA dehydrogenase, C-terminal domain. (396 aa)
AMM32920.1Putative glutaryl-CoA dehydrogenase; Pfam:pfam02771 Acyl-CoA dehydrogenase, N-terminal domain. (413 aa)
AMM32921.1Acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family. (404 aa)
AMM32922.13-oxoacyl-[acyl-carrier protein] reductase; Pfam:pfam00106 short chain dehydrogenase. (250 aa)
AMM32923.1MaoC family dehydratase; Pfam:pfam01575 MaoC like domain. (150 aa)
AMM32925.1Pfam:pfam02771 Acyl-CoA dehydrogenase, N-terminal domain. (399 aa)
AMM32926.1Pfam:pfam00171 Aldehyde dehydrogenase family. (479 aa)
acsAacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (660 aa)
AMM33043.1ACP S-malonyltransferase; Pfam:pfam00698 Acyl transferase domain. (314 aa)
fabHHypothetical protein; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (353 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (81 aa)
AMM33046.13-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (411 aa)
AMM33326.1Pfam:pfam00766 Electron transfer flavoprotein FAD-binding domain. (325 aa)
AMM33327.1Pfam:pfam01012 Electron transfer flavoprotein domain. (266 aa)
adcPutative acetoacetate decarboxylase; Catalyzes the conversion of acetoacetate to acetone and carbon dioxide; Belongs to the ADC family. (263 aa)
AMM33531.1Pfam:pfam00106 short chain dehydrogenase. (283 aa)
acpSDNA-binding protein; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (116 aa)
AMM33697.1acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
AMM33743.1Hypothetical protein; Pfam:pfam06224 Winged helix DNA-binding domain. (368 aa)
AMM33744.1acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family. (403 aa)
AMM33745.1Acyl-CoA ligase/synthetase; Pfam:pfam00501 AMP-binding enzyme. (553 aa)
AMM33746.1Pfam:pfam00441 Acyl-CoA dehydrogenase, C-terminal domain. (396 aa)
AMM33747.1Putative fatty acid oxidation complex alpha subunit; Pfam:pfam02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. (378 aa)
AMM33748.1Pfam:pfam00440 Bacterial regulatory proteins, tetR family. (248 aa)
AMM33750.1Pfam:pfam07690 Major Facilitator Superfamily. (449 aa)
AMM33751.1Acyl dehydratase; Pfam:pfam01575 MaoC like domain. (157 aa)
AMM33752.1Hypothetical protein; Pfam:pfam13452 N-terminal half of MaoC dehydratase; Belongs to the UPF0336 family. (154 aa)
AMM33753.1Transcriptional regulator, ArsR family; Pfam:pfam12840 Helix-turn-helix domain. (126 aa)
AMM33754.1MFS transporter; Pfam:pfam00916 Sulfate transporter family. (571 aa)
AMM33807.1Pfam:pfam00202 Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (452 aa)
AMM33844.1Glutamate decarboxylase; Pfam:pfam00282 Pyridoxal-dependent decarboxylase conserved domain; Belongs to the group II decarboxylase family. (477 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (387 aa)
AMM33858.1Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (701 aa)
AMM33872.1hydroxymethylglutaryl-CoA lyase; Pfam:pfam00682 HMGL-like. (319 aa)
AMM33884.1Pfam:pfam02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. (289 aa)
AMM33885.1RNA-binding protein/enoyl-CoA hydratase; Pfam:pfam00378 Enoyl-CoA hydratase/isomerase family. (297 aa)
AMM33886.1Beta-ketoadipyl CoA thiolase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family. (409 aa)
AMM33930.1acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
AMM33931.1Pfam:pfam01144 Coenzyme A transferase. (235 aa)
AMM33932.13-oxoacid CoA-transferase subunit A; Pfam:pfam01144 Coenzyme A transferase. (238 aa)
acsA-2Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (661 aa)
AMM34044.1Pfam:pfam00171 Aldehyde dehydrogenase family. (500 aa)
AMM34045.13-hydroxyisobutyryl-CoA hydrolase; Pfam:pfam13766 2-enoyl-CoA Hydratase C-terminal region. (363 aa)
AMM34046.13-hydroxyisobutyrate dehydrogenase; Pfam:pfam03446 NAD binding domain of 6-phosphogluconate dehydrogenase; Belongs to the HIBADH-related family. (307 aa)
AMM34050.1Acyl-coenzyme A oxidase; Pfam:pfam00441 Acyl-CoA dehydrogenase, C-terminal domain. (400 aa)
AMM34076.1Pfam:pfam02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. (325 aa)
AMM34156.1acetyl-COA carboxylase; Pfam:pfam02786 Carbamoyl-phosphate synthase L chain, ATP binding domain. (590 aa)
AMM34215.1Pfam:pfam00441 Acyl-CoA dehydrogenase, C-terminal domain. (685 aa)
AMM34221.1Pfam:pfam00202 Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (456 aa)
AMM34226.13-hydroxyisobutyryl-CoA hydrolase; Pfam:pfam13766 2-enoyl-CoA Hydratase C-terminal region. (347 aa)
AMM34234.1Pfam:pfam00378 Enoyl-CoA hydratase/isomerase family; Belongs to the enoyl-CoA hydratase/isomerase family. (280 aa)
AMM34366.1Pfam:pfam00109 Beta-ketoacyl synthase, N-terminal domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (404 aa)
AMM34422.1Biotin carboxyl carrier subunit of acetyl-CoA carboxylase-like protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (179 aa)
AMM34423.1acetyl-CoA carboxylase; Pfam:pfam02786 Carbamoyl-phosphate synthase L chain, ATP binding domain. (461 aa)
AMM34428.1Hypothetical protein; Pfam:pfam00501 AMP-binding enzyme. (675 aa)
AMM34521.1Pfam:pfam00171 Aldehyde dehydrogenase family. (528 aa)
AMM34637.1acetyl-CoA carboxylase; Pfam:pfam02786 Carbamoyl-phosphate synthase L chain, ATP binding domain. (450 aa)
AMM34638.1acetyl-COA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (81 aa)
AMM34652.1Pfam:pfam00171 Aldehyde dehydrogenase family. (499 aa)
AMM34666.1Pfam:pfam02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. (317 aa)
Your Current Organism:
Sinomonas atrocyanea
NCBI taxonomy Id: 37927
Other names: ATCC 13752, Arthrobacter atricyaneus, Arthrobacter atrocyaneus, CIP 102365, DSM 20127, KCTC 3377, LMG 3814, LMG:3814, NBRC 12956, S. atrocyanea
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