STRINGSTRING
prs prs selD selD AMM32229.1 AMM32229.1 AMM32251.1 AMM32251.1 AMM34249.1 AMM34249.1 pyrH pyrH AMM32292.1 AMM32292.1 AMM32325.1 AMM32325.1 AMM32336.1 AMM32336.1 argB argB nadK nadK AMM32443.1 AMM32443.1 cmk cmk AMM32465.1 AMM32465.1 AMM32470.1 AMM32470.1 AMM32502.1 AMM32502.1 AMM32514.1 AMM32514.1 AMM32539.1 AMM32539.1 AMM32603.1 AMM32603.1 coaE coaE pgk pgk AMM32738.1 AMM32738.1 AMM32787.1 AMM32787.1 glpK glpK gmk gmk AMM32822.1 AMM32822.1 AMM32838.1 AMM32838.1 AMM32937.1 AMM32937.1 AMM32948.1 AMM32948.1 proB proB AMM32996.1 AMM32996.1 ndk ndk AMM33085.1 AMM33085.1 thiL thiL AMM33184.1 AMM33184.1 thrB thrB AMM33294.1 AMM33294.1 AMM33307.1 AMM33307.1 AMM33322.1 AMM33322.1 AMM33433.1 AMM33433.1 AMM33484.1 AMM33484.1 AMM33499.1 AMM33499.1 AMM33505.1 AMM33505.1 AMM33524.1 AMM33524.1 AMM33539.1 AMM33539.1 AMM33577.1 AMM33577.1 coaA coaA AMM33638.1 AMM33638.1 AMM33651.1 AMM33651.1 adk adk AMM33715.1 AMM33715.1 ispE ispE AMM32127.1 AMM32127.1 AMM32088.1 AMM32088.1 AMM32048.1 AMM32048.1 AMM32007.1 AMM32007.1 AMM31887.1 AMM31887.1 AMM31822.1 AMM31822.1 AMM31761.1 AMM31761.1 AMM31727.1 AMM31727.1 AMM31661.1 AMM31661.1 AMM31601.1 AMM31601.1 AMM31591.1 AMM31591.1 AMM31567.1 AMM31567.1 AMM31484.1 AMM31484.1 glgB glgB AMM31465.1 AMM31465.1 tmk tmk AMM31443.1 AMM31443.1 AMM31389.1 AMM31389.1 AMM31383.1 AMM31383.1 AMM31382.1 AMM31382.1 AMM31314.1 AMM31314.1 AMM31287.1 AMM31287.1 AMM31253.1 AMM31253.1 AMM31215.1 AMM31215.1 AMM31169.1 AMM31169.1 AMM31167.1 AMM31167.1 AMM31153.1 AMM31153.1 rbsK rbsK AMM31136.1 AMM31136.1 AMM31120.1 AMM31120.1 AMM31108.1 AMM31108.1 AMM31042.1 AMM31042.1 AMM31040.1 AMM31040.1 AMM31027.1 AMM31027.1 AMM31021.1 AMM31021.1 AMM30988.1 AMM30988.1 AMM30987.1 AMM30987.1 AMM30986.1 AMM30986.1 AMM30976.1 AMM30976.1 AMM30974.1 AMM30974.1 AMM30962.1 AMM30962.1 AMM30948.1 AMM30948.1 AMM30937.1 AMM30937.1 AMM30934.1 AMM30934.1 AMM30903.1 AMM30903.1 AMM30902.1 AMM30902.1 AMM30869.1 AMM30869.1 AMM30865.1 AMM30865.1 AMM30859.1 AMM30859.1 AMM30841.1 AMM30841.1 AMM30791.1 AMM30791.1 AMM30784.1 AMM30784.1 AMM30766.1 AMM30766.1 AMM30756.1 AMM30756.1 AMM30718.1 AMM30718.1 AMM33716.1 AMM33716.1 AMM33718.1 AMM33718.1 AMM33719.1 AMM33719.1 pfkA pfkA ppk ppk AMM33765.1 AMM33765.1 ackA ackA AMM34003.1 AMM34003.1 AMM34040.1 AMM34040.1 AMM34069.1 AMM34069.1 AMM34084.1 AMM34084.1 AMM34092.1 AMM34092.1 AMM34145.1 AMM34145.1 AMM34204.1 AMM34204.1 AMM34269.1 AMM34269.1 AMM34730.1 AMM34730.1 AMM34712.1 AMM34712.1 AMM34705.1 AMM34705.1 AMM34698.1 AMM34698.1 AMM34509.1 AMM34509.1 pfkA-2 pfkA-2 AMM34437.1 AMM34437.1 AMM34415.1 AMM34415.1 AMM34352.1 AMM34352.1 AMM34342.1 AMM34342.1 AMM34284.1 AMM34284.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (326 aa)
selDSegregation protein B; Synthesizes selenophosphate from selenide and ATP. (341 aa)
AMM32229.1Pfam:pfam00069 Protein kinase domain. (584 aa)
AMM32251.1Pfam:pfam02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (343 aa)
AMM34249.1Pfam:pfam00294 pfkB family carbohydrate kinase. (342 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (267 aa)
AMM32292.1Pfam:pfam06580 Histidine kinase. (406 aa)
AMM32325.1Pfam:pfam04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase. (337 aa)
AMM32336.1Riboflavin kinase; Pfam:pfam06574 FAD synthetase; Belongs to the ribF family. (355 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (321 aa)
nadKInorganic polyphosphate kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (339 aa)
AMM32443.1Histidine kinase; Pfam:pfam14827 Sensory domain of two-component sensor kinase. (552 aa)
cmkPfam:pfam02224 Cytidylate kinase. (271 aa)
AMM32465.1Glucokinase; Pfam:pfam00480 ROK family. (361 aa)
AMM32470.1Pfam:pfam00069 Protein kinase domain. (658 aa)
AMM32502.1Polyphosphate glucokinase; Pfam:pfam00480 ROK family. (267 aa)
AMM32514.1Pfam:pfam00069 Protein kinase domain. (563 aa)
AMM32539.1Pfam:pfam00265 Thymidine kinase. (223 aa)
AMM32603.1Pfam:pfam00224 Pyruvate kinase, barrel domain; Belongs to the pyruvate kinase family. (502 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (205 aa)
pgkPfam:pfam00162 Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (414 aa)
AMM32738.1Pfam:pfam03109 ABC1 family. (570 aa)
AMM32787.1Pfam:pfam01202 Shikimate kinase. (185 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (511 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (205 aa)
AMM32822.1Pfam:pfam01202 Shikimate kinase. (84 aa)
AMM32838.1(P)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (805 aa)
AMM32937.1Pfam:pfam00781 Diacylglycerol kinase catalytic domain. (295 aa)
AMM32948.1Type III effector Hrp-dependent protein; Pfam:pfam07005 Protein of unknown function, DUF1537. (432 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (379 aa)
AMM32996.1Pfam:pfam08543 Phosphomethylpyrimidine kinase. (509 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (139 aa)
AMM33085.1Pfam:pfam02734 DAK2 domain. (341 aa)
thiLThiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (339 aa)
AMM33184.1Transporter. (532 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (332 aa)
AMM33294.1ATPase; Pfam:pfam12282 Signal transduction histidine kinase. (504 aa)
AMM33307.1Pfam:pfam02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (673 aa)
AMM33322.1Pfam:pfam00781 Diacylglycerol kinase catalytic domain. (317 aa)
AMM33433.1N-acetyl-D-glucosamine kinase Nagk; Pfam:pfam01869 BadF/BadG/BcrA/BcrD ATPase family. (308 aa)
AMM33484.1Pfam:pfam00781 Diacylglycerol kinase catalytic domain. (298 aa)
AMM33499.1Pfam:pfam02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (548 aa)
AMM33505.1Pfam:pfam02702 Osmosensitive K+ channel His kinase sensor domain. (843 aa)
AMM33524.1PfkB domain protein; Pfam:pfam00294 pfkB family carbohydrate kinase. (307 aa)
AMM33539.1Pfam:pfam00069 Protein kinase domain. (496 aa)
AMM33577.16-phosphofructokinase; Pfam:pfam00294 pfkB family carbohydrate kinase; Belongs to the carbohydrate kinase PfkB family. (320 aa)
coaAPfam:pfam00485 Phosphoribulokinase / Uridine kinase family. (321 aa)
AMM33638.1Hypothetical protein. (134 aa)
AMM33651.1Diguanylate cyclase; Pfam:pfam02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (552 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (193 aa)
AMM33715.1Histidine kinase; Pfam:pfam04024 PspC domain. (425 aa)
ispE4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (322 aa)
AMM32127.1Hypothetical protein. (64 aa)
AMM32088.1Galactokinase; Pfam:pfam10509 Galactokinase galactose-binding signature; Belongs to the GHMP kinase family. GalK subfamily. (389 aa)
AMM32048.1Pfam:pfam07730 Histidine kinase. (380 aa)
AMM32007.12-dehydro-3-deoxygluconokinase; Pfam:pfam00294 pfkB family carbohydrate kinase. (320 aa)
AMM31887.1PTS sugar transporter; Pfam:pfam00367 phosphotransferase system, EIIB. (76 aa)
AMM31822.1PfkB domain-containing protein; Pfam:pfam00294 pfkB family carbohydrate kinase. (329 aa)
AMM31761.1Pfam:pfam02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (515 aa)
AMM31727.1Hypothetical protein; Pfam:pfam13581 Histidine kinase-like ATPase domain. (153 aa)
AMM31661.1Hypothetical protein; Pfam:pfam00480 ROK family. (339 aa)
AMM31601.1Pfam:pfam02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (578 aa)
AMM31591.1Pfam:pfam02702 Osmosensitive K+ channel His kinase sensor domain. (839 aa)
AMM31567.1Carbohydrate kinase; Pfam:pfam00294 pfkB family carbohydrate kinase; Belongs to the carbohydrate kinase PfkB family. (363 aa)
AMM31484.1Lipopolysaccharide kinase; Pfam:pfam13224 Domain of unknown function (DUF4032). (464 aa)
glgB1,4-alpha-glucan branching enzyme GlgB; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (1285 aa)
AMM31465.1Pfam:pfam02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (393 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (212 aa)
AMM31443.1Two component system histidine kinase; Pfam:pfam02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (447 aa)
AMM31389.1Bifunctional protein HldE; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (211 aa)
AMM31383.1Bifunctional protein RfaE, domain II; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (254 aa)
AMM31382.1D-beta-D-heptose 1-phosphate adenosyltransferase; Pfam:pfam00294 pfkB family carbohydrate kinase. (205 aa)
AMM31314.1Pfam:pfam02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (503 aa)
AMM31287.1Hypothetical protein; Pfam:pfam01590 GAF domain. (567 aa)
AMM31253.1Pfam:pfam02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (500 aa)
AMM31215.1Pfam:pfam00696 Amino acid kinase family; Belongs to the aspartokinase family. (437 aa)
AMM31169.1Xylulokinase; Pfam:pfam00370 FGGY family of carbohydrate kinases, N-terminal domain; Belongs to the FGGY kinase family. (485 aa)
AMM31167.1MarR family transcriptional regulator; Pfam:pfam00480 ROK family. (400 aa)
AMM31153.1Hypothetical protein. (195 aa)
rbsKCarbohydrate kinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (316 aa)
AMM31136.1Hypothetical protein. (252 aa)
AMM31120.1Putative gluconokinase; Pfam:pfam01202 Shikimate kinase. (170 aa)
AMM31108.1PfkB domain-containing protein; Pfam:pfam00294 pfkB family carbohydrate kinase. (318 aa)
AMM31042.11-phosphofructokinase; Pfam:pfam00294 pfkB family carbohydrate kinase; Belongs to the carbohydrate kinase PfkB family. (320 aa)
AMM31040.1Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (571 aa)
AMM31027.1Pfam:pfam07005 Protein of unknown function, DUF1537. (487 aa)
AMM31021.1Glucokinase; Pfam:pfam00480 ROK family. (342 aa)
AMM30988.1PTS sugar transporter subunit IIA; Pfam:pfam03610 PTS system fructose IIA component. (224 aa)
AMM30987.1Dihydroxyacetone kinase; Pfam:pfam02734 DAK2 domain. (211 aa)
AMM30986.1Dihydroxyacetone kinase; Pfam:pfam02733 Dak1 domain. (333 aa)
AMM30976.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Pfam:pfam01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). (181 aa)
AMM30974.1Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (301 aa)
AMM30962.1Pfam:pfam00781 Diacylglycerol kinase catalytic domain. (348 aa)
AMM30948.1Pfam:pfam02595 Glycerate kinase family; Belongs to the glycerate kinase type-1 family. (371 aa)
AMM30937.1Ribokinase; Pfam:pfam00294 pfkB family carbohydrate kinase. (312 aa)
AMM30934.1(p)ppGpp synthetase; Pfam:pfam04607 Region found in RelA / SpoT proteins. (368 aa)
AMM30903.1Pfam:pfam00069 Protein kinase domain. (558 aa)
AMM30902.1Serine/threonine-protein kinase pknB; Pfam:pfam00069 Protein kinase domain. (664 aa)
AMM30869.1Fructose transporter. (214 aa)
AMM30865.1Thermoresistant glucokinase family carbohydrate kinase; Pfam:pfam01202 Shikimate kinase. (177 aa)
AMM30859.1Glycerol kinase; Pfam:pfam00370 FGGY family of carbohydrate kinases, N-terminal domain. (504 aa)
AMM30841.1Carbohydrate kinase; Pfam:pfam00370 FGGY family of carbohydrate kinases, N-terminal domain; Belongs to the FGGY kinase family. (504 aa)
AMM30791.1Hypothetical protein; Pfam:pfam01636 Phosphotransferase enzyme family. (317 aa)
AMM30784.1Pfam:pfam01636 Phosphotransferase enzyme family. (353 aa)
AMM30766.14-hydroxythreonine-4-phosphate dehydrogenase; Pfam:pfam04166 Pyridoxal phosphate biosynthetic protein PdxA; Belongs to the PdxA family. (757 aa)
AMM30756.1Serine/threonine-protein kinase StkP; Pfam:pfam00069 Protein kinase domain. (450 aa)
AMM30718.1Pfam:pfam00781 Diacylglycerol kinase catalytic domain. (295 aa)
AMM33716.1Hypothetical protein; Pfam:pfam04024 PspC domain. (476 aa)
AMM33718.1Phage-shock protein; Pfam:pfam04024 PspC domain. (111 aa)
AMM33719.1Hypothetical protein; Pfam:pfam04024 PspC domain. (439 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (369 aa)
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (754 aa)
AMM33765.1Pfam:pfam02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (511 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (387 aa)
AMM34003.1Pfam:pfam02595 Glycerate kinase family; Belongs to the glycerate kinase type-1 family. (381 aa)
AMM34040.1Anthranilate synthase; Pfam:pfam13207 AAA domain. (341 aa)
AMM34069.1Dihydroxyacetone kinase; Pfam:pfam02733 Dak1 domain. (576 aa)
AMM34084.1Sensor protein CitS; Pfam:pfam14827 Sensory domain of two-component sensor kinase. (537 aa)
AMM34092.1Hypothetical protein. (252 aa)
AMM34145.1Dihydroxyacetone kinase; Pfam:pfam02733 Dak1 domain. (581 aa)
AMM34204.1Hypothetical protein; Pfam:pfam01636 Phosphotransferase enzyme family. (310 aa)
AMM34269.1Hypothetical protein. (177 aa)
AMM34730.1ABC transporter substrate-binding protein. (536 aa)
AMM34712.1Phosphoesterase, PA-phosphatase related protein; Pfam:pfam01569 PAP2 superfamily. (511 aa)
AMM34705.1Pfam:pfam07730 Histidine kinase. (411 aa)
AMM34698.1Hypothetical protein. (476 aa)
AMM34509.1Pfam:pfam00196 Bacterial regulatory proteins, luxR family. (423 aa)
pfkA-26-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (341 aa)
AMM34437.1Carbohydrate kinase; Pfam:pfam00294 pfkB family carbohydrate kinase. (310 aa)
AMM34415.1Sugar kinase; Pfam:pfam02782 FGGY family of carbohydrate kinases, C-terminal domain. (485 aa)
AMM34352.1Carbohydrate kinase; Pfam:pfam02782 FGGY family of carbohydrate kinases, C-terminal domain. (494 aa)
AMM34342.1Sugar kinase; Pfam:pfam00294 pfkB family carbohydrate kinase; Belongs to the carbohydrate kinase PfkB family. (324 aa)
AMM34284.1Putative unusual protein kinase; Pfam:pfam03109 ABC1 family. (554 aa)
Your Current Organism:
Sinomonas atrocyanea
NCBI taxonomy Id: 37927
Other names: ATCC 13752, Arthrobacter atricyaneus, Arthrobacter atrocyaneus, CIP 102365, DSM 20127, KCTC 3377, LMG 3814, LMG:3814, NBRC 12956, S. atrocyanea
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