STRINGSTRING
AMM32089.1 AMM32089.1 glmU glmU dnaG dnaG AMM32287.1 AMM32287.1 AMM32336.1 AMM32336.1 pnp pnp dinB dinB AMM32498.1 AMM32498.1 glnE glnE polA polA glgC glgC rpoZ rpoZ nadD nadD coaD coaD AMM33817.1 AMM33817.1 AMM33961.1 AMM33961.1 AMM33273.1 AMM33273.1 AMM33449.1 AMM33449.1 AMM33605.1 AMM33605.1 rpoA rpoA rpoC rpoC rpoB rpoB AMM34151.1 AMM34151.1 AMM34727.1 AMM34727.1 AMM33770.1 AMM33770.1 dnaE2 dnaE2 AMM33816.1 AMM33816.1 rph rph AMM30707.1 AMM30707.1 disA disA AMM31004.1 AMM31004.1 AMM31309.1 AMM31309.1 AMM31382.1 AMM31382.1 AMM31383.1 AMM31383.1 AMM31389.1 AMM31389.1 AMM31458.1 AMM31458.1 ispD ispD AMM31499.1 AMM31499.1 AMM31939.1 AMM31939.1 AMM31962.1 AMM31962.1 AMM32064.1 AMM32064.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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AMM32089.1Pfam:pfam01087 Galactose-1-phosphate uridyl transferase, N-terminal domain. (382 aa)
glmUBifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (533 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (633 aa)
AMM32287.1Pfam:pfam01148 Cytidylyltransferase family; Belongs to the CDS family. (320 aa)
AMM32336.1Riboflavin kinase; Pfam:pfam06574 FAD synthetase; Belongs to the ribF family. (355 aa)
pnpPolyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (746 aa)
dinBDNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (402 aa)
AMM32498.1Pfam:pfam07733 Bacterial DNA polymerase III alpha subunit. (1160 aa)
glnEGlutamine-synthetase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB [...] (1014 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (882 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (480 aa)
rpoZDNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (94 aa)
nadDPutative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (212 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (166 aa)
AMM33817.1Sulfate adenylyltransferase, small subunit; Pfam:pfam01507 Phosphoadenosine phosphosulfate reductase family. (312 aa)
AMM33961.13'-5' exonuclease; Pfam:pfam00476 DNA polymerase family A. (562 aa)
AMM33273.1Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (291 aa)
AMM33449.1UTP--glucose-1-phosphate uridylyltransferase; Pfam:pfam00483 Nucleotidyl transferase. (317 aa)
AMM33605.1Hypothetical protein; Pfam:pfam00990 GGDEF domain. (384 aa)
rpoADNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (336 aa)
rpoCDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1299 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1166 aa)
AMM34151.1Pfam:pfam13298 DNA polymerase Ligase (LigD). (884 aa)
AMM34727.1RNA nucleotidyltransferase; Pfam:pfam01743 Poly A polymerase head domain; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (489 aa)
AMM33770.1DNA-directed DNA polymerase; Pfam:pfam00817 impB/mucB/samB family. (534 aa)
dnaE2DNA polymerase III subunit alpha; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1210 aa)
AMM33816.1Sulfate adenylyltransferase; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (461 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (254 aa)
AMM30707.1DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (374 aa)
disADNA integrity scanning protein DisA; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process. (358 aa)
AMM31004.1DNA polymerase III subunit delta' domain protein. (446 aa)
AMM31309.1DNA ligase; Pfam:pfam01068 ATP dependent DNA ligase domain. (725 aa)
AMM31382.1D-beta-D-heptose 1-phosphate adenosyltransferase; Pfam:pfam00294 pfkB family carbohydrate kinase. (205 aa)
AMM31383.1Bifunctional protein RfaE, domain II; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (254 aa)
AMM31389.1Bifunctional protein HldE; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (211 aa)
AMM31458.1Pfam:pfam13177 DNA polymerase III, delta subunit. (293 aa)
ispD2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (255 aa)
AMM31499.1DNA polymerase; Pfam:pfam13438 Domain of unknown function (DUF4113). (335 aa)
AMM31939.1Hypothetical protein. (353 aa)
AMM31962.1DNA polymerase IV; Pfam:pfam00817 impB/mucB/samB family. (357 aa)
AMM32064.1Mannose-1-phosphate guanylyltransferase; Pfam:pfam00483 Nucleotidyl transferase. (386 aa)
Your Current Organism:
Sinomonas atrocyanea
NCBI taxonomy Id: 37927
Other names: ATCC 13752, Arthrobacter atricyaneus, Arthrobacter atrocyaneus, CIP 102365, DSM 20127, KCTC 3377, LMG 3814, LMG:3814, NBRC 12956, S. atrocyanea
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