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AMM32112.1 AMM32112.1 fumC fumC eno eno AMM32455.1 AMM32455.1 AMM32043.1 AMM32043.1 AMM32431.1 AMM32431.1 AMM33369.1 AMM33369.1 gmd gmd AMM33752.1 AMM33752.1 menC menC AMM33846.1 AMM33846.1 aroQ aroQ ilvD-2 ilvD-2 AMM34596.1 AMM34596.1 hisB hisB AMM31654.1 AMM31654.1 AMM31636.1 AMM31636.1 AMM31291.1 AMM31291.1 AMM31176.1 AMM31176.1 hutU hutU pheA pheA AMM30898.1 AMM30898.1 AMM31986.1 AMM31986.1 AMM31903.1 AMM31903.1 AMM31836.1 AMM31836.1 AMM32552.1 AMM32552.1 AMM33350.1 AMM33350.1 AMM33272.1 AMM33272.1 AMM33216.1 AMM33216.1 AMM33149.1 AMM33149.1 ilvD ilvD leuC leuC leuD leuD mutM mutM AMM33011.1 AMM33011.1 AMM32923.1 AMM32923.1 nnrD nnrD aroC aroC aroB aroB trpA trpA trpB trpB AMM33364.1 AMM33364.1 AMM33351.1 AMM33351.1 AMM32307.1 AMM32307.1 AMM32190.1 AMM32190.1 dapA dapA
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AMM32112.1Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (204 aa)
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (477 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (426 aa)
AMM32455.1Hypothetical protein; Pfam:pfam06831 Formamidopyrimidine-DNA glycosylase H2TH domain; Belongs to the FPG family. (305 aa)
AMM32043.1Siderophore binding protein. (173 aa)
AMM32431.12-methylcitrate dehydratase; Pfam:pfam03972 MmgE/PrpD family. (506 aa)
AMM33369.1Pfam:pfam00800 Prephenate dehydratase. (284 aa)
gmdGDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (348 aa)
AMM33752.1Hypothetical protein; Pfam:pfam13452 N-terminal half of MaoC dehydratase; Belongs to the UPF0336 family. (154 aa)
menCO-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (340 aa)
AMM33846.1Crotonase; Pfam:pfam00378 Enoyl-CoA hydratase/isomerase family. (260 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (155 aa)
ilvD-2Pfam:pfam00920 Dehydratase family; Belongs to the IlvD/Edd family. (615 aa)
AMM34596.14-hydroxyphenylpyruvate dioxygenase; Pfam:pfam01261 Xylose isomerase-like TIM barrel. (666 aa)
hisBPfam:pfam00475 Imidazoleglycerol-phosphate dehydratase. (210 aa)
AMM31654.1Dihydrodipicolinate synthetase family. (116 aa)
AMM31636.1Pfam:pfam00701 Dihydrodipicolinate synthetase family; Belongs to the DapA family. (303 aa)
AMM31291.1DNA glycosylase; Pfam:pfam06831 Formamidopyrimidine-DNA glycosylase H2TH domain. (284 aa)
AMM31176.1Putative MaoC-like domain protein; Pfam:pfam01575 MaoC like domain. (161 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (591 aa)
pheAPfam:pfam00800 Prephenate dehydratase. (310 aa)
AMM30898.1Pfam:pfam01242 6-pyruvoyl tetrahydropterin synthase. (132 aa)
AMM31986.1Pfam:pfam00701 Dihydrodipicolinate synthetase family; Belongs to the DapA family. (314 aa)
AMM31903.1Pfam:pfam00701 Dihydrodipicolinate synthetase family; Belongs to the DapA family. (307 aa)
AMM31836.1Iron-sulfur cluster assembly protein HesB; Pfam:pfam00730 HhH-GPD superfamily base excision DNA repair protein. (197 aa)
AMM32552.1Aconitase; Pfam:pfam00330 Aconitase family (aconitate hydratase). (941 aa)
AMM33350.1Pfam:pfam00490 Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (326 aa)
AMM33272.1dTDP-glucose 4,6-dehydratase; Pfam:pfam01370 NAD dependent epimerase/dehydratase family; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (331 aa)
AMM33216.1Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (370 aa)
AMM33149.12-keto-4-pentenoate hydratase; Pfam:pfam01557 Fumarylacetoacetate (FAA) hydrolase family. (261 aa)
ilvDPfam:pfam00920 Dehydratase family; Belongs to the IlvD/Edd family. (579 aa)
leuC3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (479 aa)
leuDIsopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (199 aa)
mutM5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (312 aa)
AMM33011.1Pfam:pfam06831 Formamidopyrimidine-DNA glycosylase H2TH domain; Belongs to the FPG family. (313 aa)
AMM32923.1MaoC family dehydratase; Pfam:pfam01575 MaoC like domain. (150 aa)
nnrDCarbohydrate kinase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. (311 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (399 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (367 aa)
trpATryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (268 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (471 aa)
AMM33364.1Pfam:pfam01329 Pterin 4 alpha carbinolamine dehydratase. (114 aa)
AMM33351.1uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (298 aa)
AMM32307.1MaoC family dehydratase; Pfam:pfam01575 MaoC like domain. (167 aa)
AMM32190.1Pfam:pfam02602 Uroporphyrinogen-III synthase HemD. (396 aa)
dapA4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (302 aa)
Your Current Organism:
Sinomonas atrocyanea
NCBI taxonomy Id: 37927
Other names: ATCC 13752, Arthrobacter atricyaneus, Arthrobacter atrocyaneus, CIP 102365, DSM 20127, KCTC 3377, LMG 3814, LMG:3814, NBRC 12956, S. atrocyanea
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