STRINGSTRING
dxr dxr AMM32192.1 AMM32192.1 AMM32187.1 AMM32187.1 AMM32185.1 AMM32185.1 AMM31994.1 AMM31994.1 AMM31892.1 AMM31892.1 AMM31875.1 AMM31875.1 AMM31834.1 AMM31834.1 AMM31795.1 AMM31795.1 AMM31586.1 AMM31586.1 AMM31505.1 AMM31505.1 AMM31442.1 AMM31442.1 AMM33893.1 AMM33893.1 AMM34001.1 AMM34001.1 AMM34046.1 AMM34046.1 zwf-3 zwf-3 AMM34506.1 AMM34506.1 AMM34624.1 AMM34624.1 AMM34667.1 AMM34667.1 AMM31228.1 AMM31228.1 AMM33741.1 AMM33741.1 AMM30708.1 AMM30708.1 AMM30867.1 AMM30867.1 AMM31028.1 AMM31028.1 AMM31162.1 AMM31162.1 AMM31165.1 AMM31165.1 AMM31227.1 AMM31227.1 AMM34668.1 AMM34668.1 AMM33736.1 AMM33736.1 fcl fcl hemA hemA AMM33217.1 AMM33217.1 ilvC ilvC zwf-2 zwf-2 AMM33038.1 AMM33038.1 proA proA AMM32907.1 AMM32907.1 AMM32862.1 AMM32862.1 zwf zwf AMM32634.1 AMM32634.1 dapB dapB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (409 aa)
AMM32192.1Nitrite reductase; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (896 aa)
AMM32187.1Dehydrogenase; Pfam:pfam01408 Oxidoreductase family, NAD-binding Rossmann fold. (393 aa)
AMM32185.1Oxidoreductase domain protein; Pfam:pfam01408 Oxidoreductase family, NAD-binding Rossmann fold. (377 aa)
AMM31994.1Pfam:pfam03446 NAD binding domain of 6-phosphogluconate dehydrogenase. (263 aa)
AMM31892.13-hydroxyisobutyrate dehydrogenase; Pfam:pfam03446 NAD binding domain of 6-phosphogluconate dehydrogenase. (307 aa)
AMM31875.1Deaminase/reductase; Pfam:pfam01872 RibD C-terminal domain. (182 aa)
AMM31834.1Oxidoreductase domain protein; Pfam:pfam01408 Oxidoreductase family, NAD-binding Rossmann fold. (407 aa)
AMM31795.1Portal protein; Pfam:pfam13738 Pyridine nucleotide-disulphide oxidoreductase. (374 aa)
AMM31586.1Hypothetical protein; Pfam:pfam03446 NAD binding domain of 6-phosphogluconate dehydrogenase. (292 aa)
AMM31505.1Hypothetical protein; Pfam:pfam09130 Domain of unknown function (DUF1932). (257 aa)
AMM31442.1Deaminase; Pfam:pfam01872 RibD C-terminal domain. (188 aa)
AMM33893.1Dehydrogenase; Pfam:pfam01408 Oxidoreductase family, NAD-binding Rossmann fold. (359 aa)
AMM34001.1Tartronate semialdehyde reductase; Pfam:pfam03446 NAD binding domain of 6-phosphogluconate dehydrogenase. (292 aa)
AMM34046.13-hydroxyisobutyrate dehydrogenase; Pfam:pfam03446 NAD binding domain of 6-phosphogluconate dehydrogenase; Belongs to the HIBADH-related family. (307 aa)
zwf-3Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (518 aa)
AMM34506.1Pfam:pfam03446 NAD binding domain of 6-phosphogluconate dehydrogenase. (306 aa)
AMM34624.15-amino-6-(5-phosphoribosylamino)uracil reductase; Pfam:pfam01872 RibD C-terminal domain. (201 aa)
AMM34667.1NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. (464 aa)
AMM31228.1Oxidoreductase; Pfam:pfam01408 Oxidoreductase family, NAD-binding Rossmann fold. (372 aa)
AMM33741.1Pfam:pfam02774 Semialdehyde dehydrogenase, dimerization domain; Belongs to the aspartate-semialdehyde dehydrogenase family. (378 aa)
AMM30708.1Pfam:pfam03446 NAD binding domain of 6-phosphogluconate dehydrogenase. (294 aa)
AMM30867.1Pfam:pfam00742 Homoserine dehydrogenase. (334 aa)
AMM31028.1Oxidoreductase; Pfam:pfam03446 NAD binding domain of 6-phosphogluconate dehydrogenase. (302 aa)
AMM31162.1Dehydrogenase; Pfam:pfam01408 Oxidoreductase family, NAD-binding Rossmann fold. (397 aa)
AMM31165.1Oxidoreductase domain protein; Pfam:pfam01408 Oxidoreductase family, NAD-binding Rossmann fold. (380 aa)
AMM31227.1Dehydrogenase; Pfam:pfam01408 Oxidoreductase family, NAD-binding Rossmann fold. (386 aa)
AMM34668.1Putative NAD(P) transhydrogenase subunit alpha; Pfam:pfam12769 Domain of unknown function (DUF3814). (102 aa)
AMM33736.1Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (179 aa)
fclGDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (323 aa)
hemAGlutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (447 aa)
AMM33217.1Pfam:pfam00742 Homoserine dehydrogenase. (481 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (341 aa)
zwf-2Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (481 aa)
AMM33038.16-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (479 aa)
proAGamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (454 aa)
AMM32907.1Oxidoreductase; Pfam:pfam01408 Oxidoreductase family, NAD-binding Rossmann fold. (333 aa)
AMM32862.1Putative 3-hydroxyisobutyrate dehydrogenase; Pfam:pfam03446 NAD binding domain of 6-phosphogluconate dehydrogenase. (290 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (519 aa)
AMM32634.1Pfam:pfam02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa)
dapB4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (252 aa)
Your Current Organism:
Sinomonas atrocyanea
NCBI taxonomy Id: 37927
Other names: ATCC 13752, Arthrobacter atricyaneus, Arthrobacter atrocyaneus, CIP 102365, DSM 20127, KCTC 3377, LMG 3814, LMG:3814, NBRC 12956, S. atrocyanea
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