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AMM30845.1 AMM30845.1 AMM31151.1 AMM31151.1 AMM31195.1 AMM31195.1 ppc ppc AMM31285.1 AMM31285.1 gpmA gpmA AMM31644.1 AMM31644.1 glyA glyA AMM31768.1 AMM31768.1 glyA-2 glyA-2 AMM32005.1 AMM32005.1 AMM32006.1 AMM32006.1 AMM32016.1 AMM32016.1 glyA-3 glyA-3 eno eno AMM32114.1 AMM32114.1 AMM32197.1 AMM32197.1 AMM32198.1 AMM32198.1 AMM32199.1 AMM32199.1 AMM32661.1 AMM32661.1 AMM32662.1 AMM32662.1 AMM32671.1 AMM32671.1 AMM32854.1 AMM32854.1 AMM32924.1 AMM32924.1 acsA acsA AMM33106.1 AMM33106.1 mdh mdh AMM33577.1 AMM33577.1 AMM33617.1 AMM33617.1 pfkA pfkA ackA ackA AMM33858.1 AMM33858.1 acsA-2 acsA-2 AMM34049.1 AMM34049.1 AMM34109.1 AMM34109.1 AMM34110.1 AMM34110.1 AMM34390.1 AMM34390.1 AMM34426.1 AMM34426.1 AMM34427.1 AMM34427.1 AMM34496.1 AMM34496.1 AMM34497.1 AMM34497.1 AMM34498.1 AMM34498.1 pfkA-2 pfkA-2 AMM34515.1 AMM34515.1 AMM34516.1 AMM34516.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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AMM30845.1Pfam:pfam01116 Fructose-bisphosphate aldolase class-II. (288 aa)
AMM31151.1Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (340 aa)
AMM31195.1Acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (651 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (957 aa)
AMM31285.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (813 aa)
gpmAPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (248 aa)
AMM31644.1Acetyl-CoA synthetase (Acetate-CoA ligase); Pfam:pfam00501 AMP-binding enzyme. (551 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (439 aa)
AMM31768.1Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (377 aa)
glyA-2Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (438 aa)
AMM32005.16-phospho 3-hexuloisomerase; Pfam:pfam01380 SIS domain. (184 aa)
AMM32006.13-hexulose-6-phosphate synthase; Pfam:pfam00215 Orotidine 5'-phosphate decarboxylase. (215 aa)
AMM32016.1Formaldehyde dehydrogenase, glutathione-independent; Pfam:pfam08240 Alcohol dehydrogenase GroES-like domain. (404 aa)
glyA-3Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (430 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (426 aa)
AMM32114.1Pfam:pfam03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded. (345 aa)
AMM32197.1Dehydrogenase; Pfam:pfam04879 Molybdopterin oxidoreductase Fe4S4 domain. (195 aa)
AMM32198.1Formate dehydrogenase subunit alpha; Pfam:pfam01568 Molydopterin dinucleotide binding domain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (890 aa)
AMM32199.1Ferredoxin; Pfam:pfam13247 4Fe-4S dicluster domain. (332 aa)
AMM32661.1Formate dehydrogenase; Pfam:pfam01568 Molydopterin dinucleotide binding domain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1080 aa)
AMM32662.1Pfam:pfam13247 4Fe-4S dicluster domain. (272 aa)
AMM32671.1Phosphoserine phosphatase; Pfam:pfam12710 haloacid dehalogenase-like hydrolase. (246 aa)
AMM32854.1Acetyl-CoA synthetase; Pfam:pfam00501 AMP-binding enzyme. (638 aa)
AMM32924.1Pfam:pfam08240 Alcohol dehydrogenase GroES-like domain. (389 aa)
acsAacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (660 aa)
AMM33106.1Pfam:pfam00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (530 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (329 aa)
AMM33577.16-phosphofructokinase; Pfam:pfam00294 pfkB family carbohydrate kinase; Belongs to the carbohydrate kinase PfkB family. (320 aa)
AMM33617.1Pfam:pfam08240 Alcohol dehydrogenase GroES-like domain. (377 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (369 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (387 aa)
AMM33858.1Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (701 aa)
acsA-2Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (661 aa)
AMM34049.1AMP-dependent synthetase; Pfam:pfam00501 AMP-binding enzyme. (578 aa)
AMM34109.13-hexulose-6-phosphate synthase; Pfam:pfam00215 Orotidine 5'-phosphate decarboxylase. (207 aa)
AMM34110.16-phospho-3-hexuloisomerase; Pfam:pfam01380 SIS domain. (198 aa)
AMM34390.1Pfam:pfam00266 Aminotransferase class-V. (366 aa)
AMM34426.1Hypothetical protein; Pfam:pfam00391 PEP-utilizing enzyme, mobile domain. (629 aa)
AMM34427.1Hypothetical protein; Pfam:pfam01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain. (364 aa)
AMM34496.16-phospho-3-hexuloisomerase; Pfam:pfam01380 SIS domain. (199 aa)
AMM34497.1Hexulose-6-phosphate synthase; Pfam:pfam00215 Orotidine 5'-phosphate decarboxylase. (207 aa)
AMM34498.1Hexulose-6-phosphate synthase; Pfam:pfam00215 Orotidine 5'-phosphate decarboxylase. (220 aa)
pfkA-26-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (341 aa)
AMM34515.1Phosphoenolpyruvate synthase; Pfam:pfam01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain. (324 aa)
AMM34516.1Hypothetical protein; Pfam:pfam00391 PEP-utilizing enzyme, mobile domain. (636 aa)
Your Current Organism:
Sinomonas atrocyanea
NCBI taxonomy Id: 37927
Other names: ATCC 13752, Arthrobacter atricyaneus, Arthrobacter atrocyaneus, CIP 102365, DSM 20127, KCTC 3377, LMG 3814, LMG:3814, NBRC 12956, S. atrocyanea
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