node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMM30898.1 | folE | SA2016_0197 | SA2016_0272 | Pfam:pfam01242 6-pyruvoyl tetrahydropterin synthase. | Pfam:pfam01227 GTP cyclohydrolase I. | 0.982 |
AMM30901.1 | AMM30974.1 | SA2016_0200 | SA2016_0273 | Anthranilate synthase; Pfam:pfam00117 Glutamine amidotransferase class-I. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.727 |
AMM30901.1 | AMM30976.1 | SA2016_0200 | SA2016_0275 | Anthranilate synthase; Pfam:pfam00117 Glutamine amidotransferase class-I. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Pfam:pfam01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). | 0.498 |
AMM30901.1 | AMM34041.1 | SA2016_0200 | SA2016_3380 | Anthranilate synthase; Pfam:pfam00117 Glutamine amidotransferase class-I. | Anthranilate synthase; Pfam:pfam00425 chorismate binding enzyme. | 0.999 |
AMM30901.1 | AMM34043.1 | SA2016_0200 | SA2016_3382 | Anthranilate synthase; Pfam:pfam00117 Glutamine amidotransferase class-I. | 4-amino-4-deoxychorismate lyase; Pfam:pfam01063 Aminotransferase class IV. | 0.939 |
AMM30974.1 | AMM30901.1 | SA2016_0273 | SA2016_0200 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Anthranilate synthase; Pfam:pfam00117 Glutamine amidotransferase class-I. | 0.727 |
AMM30974.1 | AMM30975.1 | SA2016_0273 | SA2016_0274 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.999 |
AMM30974.1 | AMM30976.1 | SA2016_0273 | SA2016_0275 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Pfam:pfam01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). | 0.999 |
AMM30974.1 | AMM33001.1 | SA2016_0273 | SA2016_2332 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Dihydrofolate synthase; Pfam:pfam08245 Mur ligase middle domain; Belongs to the folylpolyglutamate synthase family. | 0.999 |
AMM30974.1 | AMM33736.1 | SA2016_0273 | SA2016_3071 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.601 |
AMM30974.1 | AMM34041.1 | SA2016_0273 | SA2016_3380 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Anthranilate synthase; Pfam:pfam00425 chorismate binding enzyme. | 0.617 |
AMM30974.1 | AMM34043.1 | SA2016_0273 | SA2016_3382 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 4-amino-4-deoxychorismate lyase; Pfam:pfam01063 Aminotransferase class IV. | 0.925 |
AMM30974.1 | folE | SA2016_0273 | SA2016_0272 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Pfam:pfam01227 GTP cyclohydrolase I. | 0.999 |
AMM30975.1 | AMM30974.1 | SA2016_0274 | SA2016_0273 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
AMM30975.1 | AMM30976.1 | SA2016_0274 | SA2016_0275 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Pfam:pfam01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). | 0.999 |
AMM30975.1 | AMM33001.1 | SA2016_0274 | SA2016_2332 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydrofolate synthase; Pfam:pfam08245 Mur ligase middle domain; Belongs to the folylpolyglutamate synthase family. | 0.865 |
AMM30975.1 | folE | SA2016_0274 | SA2016_0272 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Pfam:pfam01227 GTP cyclohydrolase I. | 0.997 |
AMM30976.1 | AMM30901.1 | SA2016_0275 | SA2016_0200 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Pfam:pfam01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). | Anthranilate synthase; Pfam:pfam00117 Glutamine amidotransferase class-I. | 0.498 |
AMM30976.1 | AMM30974.1 | SA2016_0275 | SA2016_0273 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Pfam:pfam01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
AMM30976.1 | AMM30975.1 | SA2016_0275 | SA2016_0274 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Pfam:pfam01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.999 |