39 items (Propithecus coquereli) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DUS2	Dihydrouridine synthase 2. (493 aa)
	GLP1R	Glucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (451 aa)
	LGALS4	Galectin. (323 aa)
	EMC3	ER membrane protein complex subunit 3; Belongs to the EMC3 family. (261 aa)
	TMTC1	Transmembrane O-mannosyltransferase targeting cadherins 1. (877 aa)
	C20orf27	Chromosome 20 open reading frame 27. (174 aa)
	GID8	GID complex subunit 8 homolog. (228 aa)
	EPHB2	EPH receptor B2. (1039 aa)
	PLAAT4	Phospholipase A and acyltransferase 4. (167 aa)
	CASP9	Caspase 9; Belongs to the peptidase C14A family. (406 aa)
	FGFR2	Fibroblast growth factor receptor. (797 aa)
	PTPN23	Protein tyrosine phosphatase non-receptor type 23. (1629 aa)
	ENSPCOP00000031755	Uncharacterized protein; Belongs to the LDH/MDH superfamily. (324 aa)
	CD164	CD164 molecule. (172 aa)
	DHX40	DEAH-box helicase 40. (653 aa)
	ENSPCOP00000002776	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (330 aa)
	GALNT6	Polypeptide N-acetylgalactosaminyltransferase. (622 aa)
	GEMIN8	Gem nuclear organelle associated protein 8. (241 aa)
	HDHD5	Haloacid dehalogenase like hydrolase domain containing 5. (419 aa)
	ENSPCOP00000009236	Uncharacterized protein. (310 aa)
	ABHD2	Abhydrolase domain containing 2. (457 aa)
	ENSPCOP00000025432	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (747 aa)
	DDX27	DEAD-box helicase 27; Belongs to the DEAD box helicase family. (788 aa)
	PPA2	Uncharacterized protein. (334 aa)
	PLXNB1	Plexin B1. (2135 aa)
	C14orf39	Chromosome 14 open reading frame 39. (566 aa)
	OSER1	Oxidative stress responsive serine rich 1. (258 aa)
	MARS1	Methionyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (900 aa)
	TCF7L2	Transcription factor 7 like 2. (619 aa)
	EIF3K	Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (218 aa)
	RHBDL2	Rhomboid-related protein 2; Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors; Belongs to the peptidase S54 family. (303 aa)
	PPP2R3C	Protein phosphatase 2 regulatory subunit B''gamma. (410 aa)
	GALNT2	Polypeptide N-acetylgalactosaminyltransferase. (571 aa)
	CCN4	Cellular communication network factor 4. (365 aa)
	ENSPCOP00000016791	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (163 aa)
	JMJD6	Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (414 aa)
	TACC1	Transforming acidic coiled-coil containing protein 1. (748 aa)
	NENF	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (164 aa)
	CTSB	Cathepsin B; Belongs to the peptidase C1 family. (339 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDX27	DHX40	ENSPCOP00000026035	ENSPCOP00000002716	DEAD-box helicase 27; Belongs to the DEAD box helicase family.	DEAH-box helicase 40.	0.701
DDX27	DUS2	ENSPCOP00000026035	ENSPCOP00000027178	DEAD-box helicase 27; Belongs to the DEAD box helicase family.	Dihydrouridine synthase 2.	0.419
DDX27	GEMIN8	ENSPCOP00000026035	ENSPCOP00000008766	DEAD-box helicase 27; Belongs to the DEAD box helicase family.	Gem nuclear organelle associated protein 8.	0.576
DDX27	MARS1	ENSPCOP00000026035	ENSPCOP00000012115	DEAD-box helicase 27; Belongs to the DEAD box helicase family.	Methionyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.416
DHX40	DDX27	ENSPCOP00000002716	ENSPCOP00000026035	DEAH-box helicase 40.	DEAD-box helicase 27; Belongs to the DEAD box helicase family.	0.701
DUS2	DDX27	ENSPCOP00000027178	ENSPCOP00000026035	Dihydrouridine synthase 2.	DEAD-box helicase 27; Belongs to the DEAD box helicase family.	0.419
ENSPCOP00000002776	ENSPCOP00000025432	ENSPCOP00000002776	ENSPCOP00000025432	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	0.942
ENSPCOP00000002776	FGFR2	ENSPCOP00000002776	ENSPCOP00000030338	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	Fibroblast growth factor receptor.	0.570
ENSPCOP00000002776	TACC1	ENSPCOP00000002776	ENSPCOP00000018685	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	Transforming acidic coiled-coil containing protein 1.	0.549
ENSPCOP00000002776	TCF7L2	ENSPCOP00000002776	ENSPCOP00000012440	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	Transcription factor 7 like 2.	0.789
ENSPCOP00000009236	HDHD5	ENSPCOP00000009236	ENSPCOP00000009026	Uncharacterized protein.	Haloacid dehalogenase like hydrolase domain containing 5.	0.481
ENSPCOP00000009236	MARS1	ENSPCOP00000009236	ENSPCOP00000012115	Uncharacterized protein.	Methionyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.745
ENSPCOP00000025432	ENSPCOP00000002776	ENSPCOP00000025432	ENSPCOP00000002776	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	0.942
ENSPCOP00000025432	FGFR2	ENSPCOP00000025432	ENSPCOP00000030338	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	Fibroblast growth factor receptor.	0.570
ENSPCOP00000025432	TACC1	ENSPCOP00000025432	ENSPCOP00000018685	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	Transforming acidic coiled-coil containing protein 1.	0.549
ENSPCOP00000025432	TCF7L2	ENSPCOP00000025432	ENSPCOP00000012440	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	Transcription factor 7 like 2.	0.789
ENSPCOP00000031755	TACC1	ENSPCOP00000031755	ENSPCOP00000018685	Uncharacterized protein; Belongs to the LDH/MDH superfamily.	Transforming acidic coiled-coil containing protein 1.	0.413
EPHB2	PLXNB1	ENSPCOP00000000714	ENSPCOP00000010881	EPH receptor B2.	Plexin B1.	0.418
EPHB2	PTPN23	ENSPCOP00000000714	ENSPCOP00000031412	EPH receptor B2.	Protein tyrosine phosphatase non-receptor type 23.	0.494
FGFR2	ENSPCOP00000002776	ENSPCOP00000030338	ENSPCOP00000002776	Fibroblast growth factor receptor.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	0.570