STRINGSTRING
ISOC2 ISOC2 AEBP1 AEBP1 MAPK6 MAPK6 YWHAG YWHAG CYP26B1 CYP26B1 CCL11 CCL11 LMAN2 LMAN2 TMEM156 TMEM156 KNG1 KNG1 P4HA3 P4HA3 ARID5B ARID5B PHF10 PHF10 PECAM1 PECAM1 MLN MLN ABCF3 ABCF3 CTNNBL1 CTNNBL1 AGER AGER TENT2 TENT2 ADRA1A ADRA1A NPNT NPNT TCF21 TCF21 OXTR OXTR GNAO1 GNAO1 TAGLN TAGLN CTSF CTSF REN REN SLC14A1 SLC14A1 ENSPCOP00000029571 ENSPCOP00000029571 CLCN3 CLCN3 AGT AGT MYH11 MYH11 AKT1 AKT1 LOC105813679 LOC105813679 PDE5A PDE5A ELAC1 ELAC1 KCNN2 KCNN2 P2RX3 P2RX3 ATF2 ATF2 PEAK1 PEAK1 DENND1A DENND1A KCNMA1 KCNMA1 TRPV1 TRPV1 RYR3 RYR3 CLCN5 CLCN5 MAFF MAFF LGALS4 LGALS4 PDZD11 PDZD11 GPBP1 GPBP1 CLCN6 CLCN6 PPP1R14A PPP1R14A ANAPC15 ANAPC15 TJP2 TJP2 CLCN2 CLCN2 PRPF40A PRPF40A KCNMB1 KCNMB1 TAC1 TAC1 KRT15 KRT15 CACNA1C CACNA1C LRFN3 LRFN3 CNN1 CNN1 P2RX1 P2RX1 KCNU1 KCNU1 ADRB3 ADRB3 KCNN4 KCNN4 RYR1 RYR1 TRPC7 TRPC7 TCTN1 TCTN1 RYR2 RYR2 APOE APOE NOS3 NOS3 SMTN SMTN IL13 IL13 DLC1 DLC1 GUCY1B1 GUCY1B1 SIKE1 SIKE1 SON SON MYO1A MYO1A ENSPCOP00000007681 ENSPCOP00000007681 OXT OXT EDN1 EDN1 IL5 IL5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ISOC2Isochorismatase domain containing 2. (205 aa)
AEBP1AE binding protein 1. (1140 aa)
MAPK6Mitogen-activated protein kinase 6. (722 aa)
YWHAGTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (247 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
CCL11C-C motif chemokine. (97 aa)
LMAN2Lectin, mannose binding 2. (356 aa)
TMEM156Transmembrane protein 156. (296 aa)
KNG1Uncharacterized protein. (391 aa)
P4HA3Prolyl 4-hydroxylase subunit alpha 3. (583 aa)
ARID5BAT-rich interaction domain 5B. (1188 aa)
PHF10PHD finger protein 10. (469 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (698 aa)
MLNMotilin. (108 aa)
ABCF3ATP binding cassette subfamily F member 3. (709 aa)
CTNNBL1Catenin beta like 1. (563 aa)
AGERAdvanced glycosylation end-product specific receptor. (403 aa)
TENT2Terminal nucleotidyltransferase 2. (411 aa)
ADRA1AAdrenoceptor alpha 1A. (466 aa)
NPNTNephronectin. (567 aa)
TCF21Transcription factor 21. (179 aa)
OXTROxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (388 aa)
GNAO1G protein subunit alpha o1. (354 aa)
TAGLNTransgelin; Belongs to the calponin family. (201 aa)
CTSFCathepsin F; Belongs to the peptidase C1 family. (482 aa)
RENRenin; Belongs to the peptidase A1 family. (405 aa)
SLC14A1Urea transporter; Belongs to the urea transporter family. (430 aa)
ENSPCOP00000029571HNOB domain-containing protein. (173 aa)
CLCN3Chloride channel protein. (724 aa)
AGTAngiotensinogen; Belongs to the serpin family. (484 aa)
MYH11Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2030 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
LOC105813679Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (744 aa)
PDE5APhosphodiesterase. (839 aa)
ELAC1ElaC ribonuclease Z 1. (363 aa)
KCNN2Potassium calcium-activated channel subfamily N member 2. (840 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (397 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
PEAK1Pseudopodium enriched atypical kinase 1. (1752 aa)
DENND1ADENN domain containing 1A. (1009 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1286 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (845 aa)
RYR3Ryanodine receptor 3. (4760 aa)
CLCN5Chloride channel protein. (816 aa)
MAFFMAF bZIP transcription factor F. (164 aa)
LGALS4Galectin. (323 aa)
PDZD11PDZ domain containing 11. (140 aa)
GPBP1GC-rich promoter binding protein 1. (493 aa)
CLCN6Chloride voltage-gated channel 6; Belongs to the chloride channel (TC 2.A.49) family. (929 aa)
PPP1R14AProtein phosphatase 1 regulatory inhibitor subunit 14A. (147 aa)
ANAPC15Uncharacterized protein. (125 aa)
TJP2Uncharacterized protein; Belongs to the MAGUK family. (1242 aa)
CLCN2Chloride channel protein. (902 aa)
PRPF40APre-mRNA processing factor 40 homolog A. (943 aa)
KCNMB1Potassium calcium-activated channel subfamily M regulatory beta subunit 1. (191 aa)
TAC1Tachykinin precursor 1. (130 aa)
KRT15Keratin 15; Belongs to the intermediate filament family. (450 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2016 aa)
LRFN3Leucine rich repeat and fibronectin type III domain containing 3. (626 aa)
CNN1Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (297 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
KCNU1Potassium calcium-activated channel subfamily U member 1. (1111 aa)
ADRB3G_PROTEIN_RECEP_F1_2 domain-containing protein. (405 aa)
KCNN4Potassium calcium-activated channel subfamily N member 4. (427 aa)
RYR1Ryanodine receptor 1. (4928 aa)
TRPC7Transient receptor potential cation channel subfamily C member 7; Belongs to the transient receptor (TC 1.A.4) family. (862 aa)
TCTN1Tectonic family member 1. (587 aa)
RYR2Ryanodine receptor 2. (4825 aa)
APOEApolipoprotein E. (314 aa)
NOS3Nitric oxide synthase 3. (994 aa)
SMTNSmoothelin. (978 aa)
IL13Interleukin 13. (132 aa)
DLC1DLC1 Rho GTPase activating protein. (1125 aa)
GUCY1B1Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (176 aa)
SIKE1Suppressor of IKBKE 1. (130 aa)
SONSON DNA binding protein. (2419 aa)
MYO1AMyosin IA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1043 aa)
ENSPCOP00000007681EF-hand domain-containing protein. (132 aa)
OXTOxytocin/neurophysin I prepropeptide; Belongs to the vasopressin/oxytocin family. (125 aa)
EDN1Endothelin 1. (193 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (133 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
Server load: low (20%) [HD]