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PDGFB PDGFB VEGFB VEGFB TEK TEK PDGFC PDGFC FLT4 FLT4 PGF PGF ANGPT4 ANGPT4 PDGFRL PDGFRL PDGFD PDGFD PIR PIR NRP2 NRP2 FLT1 FLT1 TIE1 TIE1 ANGPT2 ANGPT2 HGF HGF VEGFC VEGFC ANGPT1 ANGPT1 MET MET VEGFA VEGFA PDGFA PDGFA PDGFRA PDGFRA VEGFD VEGFD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (188 aa)
TEKTEK receptor tyrosine kinase. (1125 aa)
PDGFCPlatelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (284 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1341 aa)
PGFPlacental growth factor; Belongs to the PDGF/VEGF growth factor family. (220 aa)
ANGPT4Angiopoietin 4. (499 aa)
PDGFRLPlatelet derived growth factor receptor like. (356 aa)
PDGFDPlatelet derived growth factor D. (349 aa)
PIRPirin; Belongs to the pirin family. (290 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (932 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1143 aa)
ANGPT2Angiopoietin 2. (496 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (703 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (367 aa)
ANGPT1Angiopoietin 1. (408 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1397 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (395 aa)
PDGFAPlatelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa)
PDGFRAPlatelet derived growth factor receptor alpha; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1027 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (319 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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