STRINGSTRING
ARHGEF6 ARHGEF6 GIT1 GIT1 IQGAP1 IQGAP1 RHOV RHOV ENSPCOP00000002927 ENSPCOP00000002927 PAK4 PAK4 PAK1 PAK1 RAC2 RAC2 GIT2 GIT2 CALM2 CALM2 PAK6 PAK6 RAC1 RAC1 MYO9A MYO9A PAK2 PAK2 PREX1 PREX1 CDC42 CDC42 PAK3 PAK3 IQGAP2 IQGAP2 ARHGEF7 ARHGEF7 IQGAP3 IQGAP3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ARHGEF6Rac/Cdc42 guanine nucleotide exchange factor 6. (776 aa)
GIT1GIT ArfGAP 1. (752 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1400 aa)
RHOVRas homolog family member V. (236 aa)
ENSPCOP00000002927Uncharacterized protein. (160 aa)
PAK4Non-specific serine/threonine protein kinase. (588 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
RAC2Rac family small GTPase 2. (192 aa)
GIT2GIT ArfGAP 2. (759 aa)
CALM2Calmodulin 2; Belongs to the calmodulin family. (138 aa)
PAK6Non-specific serine/threonine protein kinase. (681 aa)
RAC1Rac family small GTPase 1. (211 aa)
MYO9AMyosin IXA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2549 aa)
PAK2Non-specific serine/threonine protein kinase. (492 aa)
PREX1Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1626 aa)
CDC42Uncharacterized protein. (191 aa)
PAK3P21 (RAC1) activated kinase 3. (580 aa)
IQGAP2IQ motif containing GTPase activating protein 2. (1560 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (782 aa)
IQGAP3IQ motif containing GTPase activating protein 3. (1607 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.