STRINGSTRING
TRAF6 TRAF6 ENSPCOP00000002497 ENSPCOP00000002497 BIRC3 BIRC3 RELB RELB IRF3 IRF3 MAP3K7 MAP3K7 CD180 CD180 TLR9 TLR9 TRAF3 TRAF3 RNF151 RNF151 NFKB1 NFKB1 TLR3 TLR3 NFKBIB NFKBIB PELI1 PELI1 LY96 LY96 TAB3 TAB3 NFKBIE NFKBIE TLR1 TLR1 LOC105826184 LOC105826184 NFKBIA NFKBIA LOC105817503 LOC105817503 TRAF2 TRAF2 TNIP2 TNIP2 TLR8 TLR8 TRADD TRADD MLKL MLKL TBK1 TBK1 ENSPCOP00000017161 ENSPCOP00000017161 ANKRD6 ANKRD6 TMED7 TMED7 BCL3 BCL3 IRAK2 IRAK2 PELI2 PELI2 MAVS MAVS IRAK3 IRAK3 DMPK DMPK CEACAM16 CEACAM16 TAB1 TAB1 IKBKB IKBKB DNASE1L1 DNASE1L1 CD14 CD14 LY86 LY86 TAB2 TAB2 TANK TANK NFKBIZ NFKBIZ UNC93B1 UNC93B1 TIRAP TIRAP REL REL NFKBID NFKBID RIPK1 RIPK1 MAP3K14 MAP3K14 NFKB2 NFKB2 TICAM1 TICAM1 IKBKG IKBKG TNFRSF1A TNFRSF1A IKBKE IKBKE TLR4 TLR4 IRAK4 IRAK4 TRAF1 TRAF1 IRAK1 IRAK1 CHUK CHUK MYD88 MYD88 CYLD CYLD TRAF5 TRAF5 RIPK3 RIPK3 ENSPCOP00000031440 ENSPCOP00000031440 RELA RELA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TRAF6TNF receptor-associated factor. (498 aa)
ENSPCOP00000002497Uncharacterized protein. (317 aa)
BIRC3Baculoviral IAP repeat containing 3. (597 aa)
RELBRELB proto-oncogene, NF-kB subunit. (552 aa)
IRF3IRF tryptophan pentad repeat domain-containing protein. (419 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (553 aa)
CD180CD180 molecule. (661 aa)
TLR9TIR domain-containing protein. (1029 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (564 aa)
RNF151Ring finger protein 151. (235 aa)
NFKB1Nuclear factor kappa B subunit 1. (961 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (905 aa)
NFKBIBNFKB inhibitor beta. (346 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
LY96Lymphocyte antigen 96. (160 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (710 aa)
NFKBIENFKB inhibitor epsilon. (434 aa)
TLR1Toll-like receptor. (774 aa)
LOC105826184TIR domain-containing protein. (950 aa)
NFKBIANFKB inhibitor alpha. (314 aa)
LOC105817503Uncharacterized protein. (349 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
TNIP2TNFAIP3 interacting protein 2. (432 aa)
TLR8Toll like receptor 8; Belongs to the Toll-like receptor family. (1039 aa)
TRADDTNFRSF1A associated via death domain. (309 aa)
MLKLMixed lineage kinase domain like pseudokinase. (419 aa)
TBK1TANK binding kinase 1. (690 aa)
ENSPCOP00000017161Mitogen-activated protein kinase kinase kinase 8. (119 aa)
ANKRD6Ankyrin repeat domain 6. (726 aa)
TMED7Transmembrane p24 trafficking protein 7. (224 aa)
BCL3BCL3 transcription coactivator. (454 aa)
IRAK2Interleukin 1 receptor associated kinase 2. (532 aa)
PELI2Pellino E3 ubiquitin protein ligase family member 2. (386 aa)
MAVSMitochondrial antiviral signaling protein. (514 aa)
IRAK3Interleukin 1 receptor associated kinase 3. (505 aa)
DMPKDM1 protein kinase. (630 aa)
CEACAM16Carcinoembryonic antigen related cell adhesion molecule 16. (420 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (747 aa)
DNASE1L1Deoxyribonuclease; Belongs to the DNase I family. (306 aa)
CD14Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (375 aa)
LY86Lymphocyte antigen 86. (166 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
TANKTRAF family member associated NFKB activator. (425 aa)
NFKBIZNFKB inhibitor zeta. (715 aa)
UNC93B1Unc-93 homolog B1, TLR signaling regulator. (600 aa)
TIRAPTIR domain containing adaptor protein. (198 aa)
RELREL proto-oncogene, NF-kB subunit. (592 aa)
NFKBIDNFKB inhibitor delta. (460 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (643 aa)
MAP3K14Uncharacterized protein. (151 aa)
NFKB2Nuclear factor kappa B subunit 2. (895 aa)
TICAM1TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (692 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (490 aa)
TNFRSF1ATNF receptor superfamily member 1A. (447 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (840 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (406 aa)
TRAF1TNF receptor-associated factor. (415 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (713 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (682 aa)
MYD88MYD88 innate immune signal transduction adaptor. (353 aa)
CYLDCYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (956 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (536 aa)
RIPK3Receptor interacting serine/threonine kinase 3. (516 aa)
ENSPCOP00000031440annotation not available (119 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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