STRINGSTRING
TGFB2 TGFB2 TGFBR2 TGFBR2 INHBE INHBE ACVR2B ACVR2B FST FST TGFB3 TGFB3 NODAL NODAL ACVR2A ACVR2A INHBB INHBB INHBC INHBC ACVR1B ACVR1B TGFBR3 TGFBR3 INHA INHA TGFBR1 TGFBR1 INHBA INHBA TGFB1 TGFB1 ACVR1C ACVR1C LOC105810381 LOC105810381
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
INHBEInhibin subunit beta E. (351 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (529 aa)
FSTFollistatin. (344 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
NODALNodal growth differentiation factor. (348 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (416 aa)
INHBBInhibin subunit beta B. (408 aa)
INHBCInhibin subunit beta C. (351 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (545 aa)
TGFBR3Transforming growth factor beta receptor 3. (851 aa)
INHAInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (368 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (421 aa)
INHBAInhibin subunit beta A. (426 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (484 aa)
LOC105810381Left-right determination factor 2. (364 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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