STRINGSTRING
WNT2B WNT2B RGS21 RGS21 FHL3 FHL3 WNT7B WNT7B RGS4 RGS4 RGS16 RGS16 WNT10B WNT10B PRICKLE1 PRICKLE1 GPC3 GPC3 WNT7A WNT7A LRP2 LRP2 TES TES PRICKLE3 PRICKLE3 FZD9 FZD9 LRP12 LRP12 FZD5 FZD5 ENAH ENAH RGS14 RGS14 ENSPCOP00000004928 ENSPCOP00000004928 RGS18 RGS18 KIAA1549 KIAA1549 FZD7 FZD7 VASP VASP ROR1 ROR1 NOTUM NOTUM ENSPCOP00000005705 ENSPCOP00000005705 WNT11 WNT11 PRICKLE2 PRICKLE2 PRICKLE4 PRICKLE4 DVL2 DVL2 DAND5 DAND5 DKK3 DKK3 AGRN AGRN LOC105823621 LOC105823621 VANGL1 VANGL1 AXIN2 AXIN2 WNT5A WNT5A WNT1 WNT1 LRP6 LRP6 RGS3 RGS3 WNT16 WNT16 WNT9A WNT9A FRZB FRZB RGS9 RGS9 FZD8 FZD8 FZD3 FZD3 LOC105823019 LOC105823019 PORCN PORCN KREMEN1 KREMEN1 APOE APOE ENSPCOP00000010387 ENSPCOP00000010387 RGS17 RGS17 KLF3 KLF3 DKK2 DKK2 WIF1 WIF1 WNT6 WNT6 FBXW11 FBXW11 ENSPCOP00000011475 ENSPCOP00000011475 LOC105823622 LOC105823622 RGS2 RGS2 ROR2 ROR2 RYK RYK GSK3A GSK3A RGS12 RGS12 RGS8 RGS8 RGS11 RGS11 LDLRAD3 LDLRAD3 GNB5 GNB5 RGS7BP RGS7BP FZD6 FZD6 KREMEN2 KREMEN2 CTNNBIP1 CTNNBIP1 RGS13 RGS13 AMER1 AMER1 DVL3 DVL3 RGS5 RGS5 CELSR1 CELSR1 SFRP5 SFRP5 RGS10 RGS10 BCHE BCHE ARHGAP1 ARHGAP1 BTRC BTRC SFRP4 SFRP4 FZD2 FZD2 SFRP2 SFRP2 LRP3 LRP3 RGS6 RGS6 NKD1 NKD1 DKK4 DKK4 RGS20 RGS20 LDLRAP1 LDLRAP1 VANGL2 VANGL2 OGFRL1 OGFRL1 DKK1 DKK1 CER1 CER1 NKD2 NKD2 WNT4 WNT4 LRPAP1 LRPAP1 MUSK MUSK WNT9B WNT9B CTNNB1 CTNNB1 GSK3B GSK3B APC2 APC2 C7orf57 C7orf57 WLS WLS RGS7 RGS7 EVL EVL DOK7 DOK7 WNT3 WNT3 COLQ COLQ INVS INVS RELN RELN GNAQ GNAQ LRP8 LRP8 WNT3A WNT3A CELSR3 CELSR3 WNT8A WNT8A DVL1 DVL1 MFRP MFRP PDCL PDCL VLDLR VLDLR LRP5 LRP5 DAB1 DAB1 WNT8B WNT8B APC APC ENSPCOP00000028883 ENSPCOP00000028883 ATCAY ATCAY WNT10A WNT10A LDLR LDLR AXIN1 AXIN1 WNT2 WNT2 PPP1R1C PPP1R1C SFRP1 SFRP1 RGS1 RGS1 LRP1 LRP1 ZNF74 ZNF74 WNT5B WNT5B FHL1 FHL1 LRP4 LRP4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
RGS21Regulator of G protein signaling 21. (85 aa)
FHL3Four and a half LIM domains 3. (280 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
RGS4Regulator of G protein signaling 4. (290 aa)
RGS16Regulator of G protein signaling 16. (202 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
PRICKLE1Prickle planar cell polarity protein 1. (831 aa)
GPC3Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (580 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (190 aa)
LRP2LDL receptor related protein 2. (4654 aa)
TESTestin LIM domain protein. (393 aa)
PRICKLE3Prickle planar cell polarity protein 3. (609 aa)
FZD9Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (591 aa)
LRP12LDL receptor related protein 12. (859 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
ENAHENAH actin regulator. (698 aa)
RGS14Regulator of G protein signaling 14. (567 aa)
ENSPCOP00000004928Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (258 aa)
RGS18Regulator of G protein signaling 18. (166 aa)
KIAA1549KIAA1549. (1911 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
VASPVasodilator stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (379 aa)
ROR1Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (937 aa)
NOTUMNotum, palmitoleoyl-protein carboxylesterase. (499 aa)
ENSPCOP00000005705CRAL-TRIO domain-containing protein. (176 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
PRICKLE2Prickle planar cell polarity protein 2. (902 aa)
PRICKLE4Uncharacterized protein. (386 aa)
DVL2Dishevelled segment polarity protein 2. (736 aa)
DAND5DAN domain BMP antagonist family member 5. (185 aa)
DKK3Dickkopf WNT signaling pathway inhibitor 3. (348 aa)
AGRNAgrin. (2040 aa)
LOC105823621C-type lectin domain-containing protein. (529 aa)
VANGL1Vang-like protein. (524 aa)
AXIN2Axin 2. (716 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1579 aa)
RGS3Regulator of G protein signaling 3. (913 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
FRZBFrizzled related protein. (325 aa)
RGS9Regulator of G protein signaling 9. (641 aa)
FZD8Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (406 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
LOC105823019Uncharacterized protein. (87 aa)
PORCNPorcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family. (468 aa)
KREMEN1Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (458 aa)
APOEApolipoprotein E. (314 aa)
ENSPCOP00000010387Uncharacterized protein. (145 aa)
RGS17Regulator of G protein signaling 17. (148 aa)
KLF3Kruppel like factor 3. (343 aa)
DKK2Dickkopf WNT signaling pathway inhibitor 2. (259 aa)
WIF1WNT inhibitory factor 1. (382 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
FBXW11F-box and WD repeat domain containing 11. (542 aa)
ENSPCOP00000011475Protein kinase domain-containing protein. (89 aa)
LOC105823622Integral membrane protein DGCR2/IDD-like. (207 aa)
RGS2Regulator of G protein signaling 2. (211 aa)
ROR2Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (943 aa)
RYKReceptor like tyrosine kinase. (606 aa)
GSK3AGlycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (483 aa)
RGS12Regulator of G protein signaling 12. (1436 aa)
RGS8Regulator of G protein signaling 8. (198 aa)
RGS11Regulator of G protein signaling 11. (467 aa)
LDLRAD3Low density lipoprotein receptor class A domain containing 3. (345 aa)
GNB5G protein subunit beta 5. (395 aa)
RGS7BPRegulator of G protein signaling 7 binding protein. (257 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa)
KREMEN2Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (460 aa)
CTNNBIP1Catenin beta interacting protein 1. (81 aa)
RGS13Regulator of G protein signaling 13. (159 aa)
AMER1APC membrane recruitment protein 1. (796 aa)
DVL3Dishevelled segment polarity protein 3. (716 aa)
RGS5Regulator of G protein signaling 5. (181 aa)
CELSR1Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (2924 aa)
SFRP5Secreted frizzled related protein 5. (315 aa)
RGS10Regulator of G protein signaling 10. (181 aa)
BCHECarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (602 aa)
ARHGAP1Rho GTPase activating protein 1. (444 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (609 aa)
SFRP4Secreted frizzled related protein 4. (342 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (547 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
LRP3LDL receptor related protein 3. (745 aa)
RGS6Regulator of G protein signaling 6. (490 aa)
NKD1NKD inhibitor of WNT signaling pathway 1. (471 aa)
DKK4Dickkopf WNT signaling pathway inhibitor 4. (224 aa)
RGS20Regulator of G protein signaling 20. (373 aa)
LDLRAP1Low density lipoprotein receptor adaptor protein 1. (308 aa)
VANGL2Vang-like protein. (550 aa)
OGFRL1Opioid growth factor receptor like 1. (399 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (268 aa)
CER1Cerberus 1, DAN family BMP antagonist. (267 aa)
NKD2NKD inhibitor of WNT signaling pathway 2. (398 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
LRPAP1LDL receptor related protein associated protein 1. (359 aa)
MUSKMuscle associated receptor tyrosine kinase. (826 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
CTNNB1Catenin beta 1. (781 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (390 aa)
APC2APC regulator of WNT signaling pathway 2. (2300 aa)
C7orf57Chromosome 7 open reading frame 57. (295 aa)
WLSWnt ligand secretion mediator. (543 aa)
RGS7Regulator of G protein signaling 7. (487 aa)
EVLEnah/Vasp-like; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (419 aa)
DOK7Docking protein 7. (500 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
COLQCollagen like tail subunit of asymmetric acetylcholinesterase. (459 aa)
INVSInversin. (1008 aa)
RELNReelin. (3445 aa)
GNAQG protein subunit alpha q. (359 aa)
LRP8LDL receptor related protein 8. (956 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
CELSR3Cadherin EGF LAG seven-pass G-type receptor 3; Belongs to the G-protein coupled receptor 2 family. (3313 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
DVL1Dishevelled segment polarity protein 1. (722 aa)
MFRPMembrane frizzled-related protein. (578 aa)
PDCLPhosducin like. (301 aa)
VLDLRVery low density lipoprotein receptor. (879 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1606 aa)
DAB1DAB adaptor protein 1. (588 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
APCAPC regulator of WNT signaling pathway. (2844 aa)
ENSPCOP00000028883Protein kinase domain-containing protein. (138 aa)
ATCAYATCAY kinesin light chain interacting caytaxin. (338 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
LDLRLow density lipoprotein receptor. (902 aa)
AXIN1Axin 1. (865 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
PPP1R1CProtein phosphatase 1 regulatory inhibitor subunit 1C. (109 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
RGS1Regulator of G protein signaling 1. (187 aa)
LRP1LDL receptor related protein 1. (4544 aa)
ZNF74Zinc finger protein 74. (646 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (332 aa)
FHL1Four and a half LIM domains 1. (323 aa)
LRP4LDL receptor related protein 4. (1922 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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