15 items (Propithecus coquereli) - STRING interaction network

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	ASMT	Acetylserotonin O-methyltransferase. (283 aa)
	KYAT3	Kynurenine aminotransferase 3. (420 aa)
	ACMSD	2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. (336 aa)
	TDO2	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (406 aa)
	HAAO	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (286 aa)
	METTL11B	Methyltransferase like 11B. (262 aa)
	IDO2	Indoleamine 2,3-dioxygenase 2. (425 aa)
	KMO	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. (467 aa)
	AANAT	Aralkylamine N-acetyltransferase. (243 aa)
	ASMTL	Acetylserotonin O-methyltransferase like. (621 aa)
	KYNU	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family. (424 aa)
	KYAT1	Aminotran_1_2 domain-containing protein. (515 aa)
	AADACL4	Arylacetamide deacetylase like 4. (407 aa)
	AADAT	Aminoadipate aminotransferase. (406 aa)
	AFMID	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. (305 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AADACL4	AADAT	ENSPCOP00000026679	ENSPCOP00000028800	Arylacetamide deacetylase like 4.	Aminoadipate aminotransferase.	0.668
AADACL4	ASMT	ENSPCOP00000026679	ENSPCOP00000001529	Arylacetamide deacetylase like 4.	Acetylserotonin O-methyltransferase.	0.424
AADACL4	ASMTL	ENSPCOP00000026679	ENSPCOP00000016898	Arylacetamide deacetylase like 4.	Acetylserotonin O-methyltransferase like.	0.431
AADACL4	IDO2	ENSPCOP00000026679	ENSPCOP00000009591	Arylacetamide deacetylase like 4.	Indoleamine 2,3-dioxygenase 2.	0.555
AADACL4	KMO	ENSPCOP00000026679	ENSPCOP00000012522	Arylacetamide deacetylase like 4.	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.	0.782
AADACL4	KYAT1	ENSPCOP00000026679	ENSPCOP00000025573	Arylacetamide deacetylase like 4.	Aminotran_1_2 domain-containing protein.	0.541
AADACL4	KYAT3	ENSPCOP00000026679	ENSPCOP00000002326	Arylacetamide deacetylase like 4.	Kynurenine aminotransferase 3.	0.541
AADACL4	KYNU	ENSPCOP00000026679	ENSPCOP00000018146	Arylacetamide deacetylase like 4.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family.	0.888
AADACL4	METTL11B	ENSPCOP00000026679	ENSPCOP00000008429	Arylacetamide deacetylase like 4.	Methyltransferase like 11B.	0.424
AADACL4	TDO2	ENSPCOP00000026679	ENSPCOP00000004095	Arylacetamide deacetylase like 4.	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.	0.883
AADAT	AADACL4	ENSPCOP00000028800	ENSPCOP00000026679	Aminoadipate aminotransferase.	Arylacetamide deacetylase like 4.	0.668
AADAT	AFMID	ENSPCOP00000028800	ENSPCOP00000029041	Aminoadipate aminotransferase.	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	0.904
AADAT	HAAO	ENSPCOP00000028800	ENSPCOP00000004572	Aminoadipate aminotransferase.	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family.	0.556
AADAT	IDO2	ENSPCOP00000028800	ENSPCOP00000009591	Aminoadipate aminotransferase.	Indoleamine 2,3-dioxygenase 2.	0.829
AADAT	KMO	ENSPCOP00000028800	ENSPCOP00000012522	Aminoadipate aminotransferase.	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.	0.935
AADAT	KYAT1	ENSPCOP00000028800	ENSPCOP00000025573	Aminoadipate aminotransferase.	Aminotran_1_2 domain-containing protein.	0.933
AADAT	KYAT3	ENSPCOP00000028800	ENSPCOP00000002326	Aminoadipate aminotransferase.	Kynurenine aminotransferase 3.	0.922
AADAT	KYNU	ENSPCOP00000028800	ENSPCOP00000018146	Aminoadipate aminotransferase.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family.	0.928
AADAT	TDO2	ENSPCOP00000028800	ENSPCOP00000004095	Aminoadipate aminotransferase.	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.	0.402
AANAT	ASMT	ENSPCOP00000016424	ENSPCOP00000001529	Aralkylamine N-acetyltransferase.	Acetylserotonin O-methyltransferase.	0.938