(6 nodes) Mixed, incl. Dopamine neurotransmitter receptor activity, coupled via Gi/Go, and Mu-type opioid receptor binding network (Propithecus coquereli)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DRD2	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
	GNB2	G protein subunit beta 2. (340 aa)
	ENSPCOP00000007290	Uncharacterized protein. (174 aa)
	DRD3	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (400 aa)
	GNG2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (109 aa)
	GNAO1	G protein subunit alpha o1. (354 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DRD2	DRD3	ENSPCOP00000002488	ENSPCOP00000009227	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	0.875
DRD2	ENSPCOP00000007290	ENSPCOP00000002488	ENSPCOP00000007290	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.977
DRD2	GNAO1	ENSPCOP00000002488	ENSPCOP00000030514	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.	G protein subunit alpha o1.	0.981
DRD2	GNB2	ENSPCOP00000002488	ENSPCOP00000005314	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.	G protein subunit beta 2.	0.973
DRD2	GNG2	ENSPCOP00000002488	ENSPCOP00000023922	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.964
DRD3	DRD2	ENSPCOP00000009227	ENSPCOP00000002488	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.	0.875
DRD3	ENSPCOP00000007290	ENSPCOP00000009227	ENSPCOP00000007290	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.943
DRD3	GNAO1	ENSPCOP00000009227	ENSPCOP00000030514	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	G protein subunit alpha o1.	0.968
DRD3	GNB2	ENSPCOP00000009227	ENSPCOP00000005314	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	G protein subunit beta 2.	0.959
DRD3	GNG2	ENSPCOP00000009227	ENSPCOP00000023922	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.963
ENSPCOP00000007290	DRD2	ENSPCOP00000007290	ENSPCOP00000002488	Uncharacterized protein.	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.	0.977
ENSPCOP00000007290	DRD3	ENSPCOP00000007290	ENSPCOP00000009227	Uncharacterized protein.	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	0.943
ENSPCOP00000007290	GNAO1	ENSPCOP00000007290	ENSPCOP00000030514	Uncharacterized protein.	G protein subunit alpha o1.	0.874
ENSPCOP00000007290	GNB2	ENSPCOP00000007290	ENSPCOP00000005314	Uncharacterized protein.	G protein subunit beta 2.	0.966
ENSPCOP00000007290	GNG2	ENSPCOP00000007290	ENSPCOP00000023922	Uncharacterized protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.981
GNAO1	DRD2	ENSPCOP00000030514	ENSPCOP00000002488	G protein subunit alpha o1.	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.	0.981
GNAO1	DRD3	ENSPCOP00000030514	ENSPCOP00000009227	G protein subunit alpha o1.	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	0.968
GNAO1	ENSPCOP00000007290	ENSPCOP00000030514	ENSPCOP00000007290	G protein subunit alpha o1.	Uncharacterized protein.	0.874
GNAO1	GNB2	ENSPCOP00000030514	ENSPCOP00000005314	G protein subunit alpha o1.	G protein subunit beta 2.	0.986
GNAO1	GNG2	ENSPCOP00000030514	ENSPCOP00000023922	G protein subunit alpha o1.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.985