(20 nodes) Mixed, incl. Ribosome biogenesis, and Domain of unknown function DUF4217 network (Propithecus coquereli)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

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protein homology

Your Input:
	NOP2	NOP2 nucleolar protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (847 aa)
	NIP7	60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (180 aa)
	DDX55	RNA helicase. (600 aa)
	RPF2	Ribosome production factor 2 homolog. (283 aa)
	MRTO4	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (239 aa)
	LOC105805830	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (612 aa)
	DDX18	RNA helicase. (671 aa)
	PES1	Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. (588 aa)
	ENSPCOP00000010560	Brix domain-containing protein. (297 aa)
	ENSPCOP00000012921	Ribosomal_L28e domain-containing protein. (150 aa)
	NOC3L	Nucleolar complex protein 3 homolog. (715 aa)
	WDR12	Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (398 aa)
	ENSPCOP00000018567	TRASH domain-containing protein. (165 aa)
	RSL1D1	Ribosomal L1 domain containing 1. (357 aa)
	EBNA1BP2	EBNA1 binding protein 2. (334 aa)
	BOP1	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (737 aa)
	NIFK	Nucleolar protein interacting with the FHA domain of MKI67. (185 aa)
	FTSJ3	pre-rRNA processing protein FTSJ3; Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (838 aa)
	WDR74	WD repeat domain 74. (384 aa)
	GNL3	G protein nucleolar 3. (549 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BOP1	DDX18	ENSPCOP00000022224	ENSPCOP00000009639	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	RNA helicase.	0.999
BOP1	DDX55	ENSPCOP00000022224	ENSPCOP00000003751	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	RNA helicase.	0.995
BOP1	EBNA1BP2	ENSPCOP00000022224	ENSPCOP00000022058	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	EBNA1 binding protein 2.	0.999
BOP1	ENSPCOP00000010560	ENSPCOP00000022224	ENSPCOP00000010560	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Brix domain-containing protein.	0.994
BOP1	ENSPCOP00000012921	ENSPCOP00000022224	ENSPCOP00000012921	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosomal_L28e domain-containing protein.	0.989
BOP1	ENSPCOP00000018567	ENSPCOP00000022224	ENSPCOP00000018567	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	TRASH domain-containing protein.	0.988
BOP1	FTSJ3	ENSPCOP00000022224	ENSPCOP00000023544	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	pre-rRNA processing protein FTSJ3; Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.	0.998
BOP1	GNL3	ENSPCOP00000022224	ENSPCOP00000028114	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	G protein nucleolar 3.	0.998
BOP1	LOC105805830	ENSPCOP00000022224	ENSPCOP00000006437	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.	0.994
BOP1	MRTO4	ENSPCOP00000022224	ENSPCOP00000006133	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.	0.999
BOP1	NIFK	ENSPCOP00000022224	ENSPCOP00000022555	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Nucleolar protein interacting with the FHA domain of MKI67.	0.998
BOP1	NIP7	ENSPCOP00000022224	ENSPCOP00000003695	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family.	0.997
BOP1	NOC3L	ENSPCOP00000022224	ENSPCOP00000014388	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Nucleolar complex protein 3 homolog.	0.998
BOP1	NOP2	ENSPCOP00000022224	ENSPCOP00000000815	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	NOP2 nucleolar protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	0.994
BOP1	PES1	ENSPCOP00000022224	ENSPCOP00000009664	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family.	0.999
BOP1	RPF2	ENSPCOP00000022224	ENSPCOP00000004460	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosome production factor 2 homolog.	0.996
BOP1	RSL1D1	ENSPCOP00000022224	ENSPCOP00000020925	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosomal L1 domain containing 1.	0.998
BOP1	WDR12	ENSPCOP00000022224	ENSPCOP00000017073	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.999
BOP1	WDR74	ENSPCOP00000022224	ENSPCOP00000025226	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	WD repeat domain 74.	0.999
DDX18	BOP1	ENSPCOP00000009639	ENSPCOP00000022224	RNA helicase.	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.999