STRINGSTRING
DIRAS1 DIRAS1 ENSPCOP00000000722 ENSPCOP00000000722 PAG1 PAG1 FRS3 FRS3 SLA2 SLA2 SH3BP2 SH3BP2 CD3D CD3D OSCAR OSCAR TEC TEC SH2D2A SH2D2A SH3GL3 SH3GL3 GRB7 GRB7 CD8A CD8A SHC4 SHC4 VAV2 VAV2 PIK3R3 PIK3R3 FCGR2A FCGR2A LRIG3 LRIG3 CD4 CD4 PTPN1 PTPN1 SOS1 SOS1 SYK SYK LOC105821782 LOC105821782 LCK LCK SOS2 SOS2 FRK FRK NTRK1 NTRK1 PTPN18 PTPN18 CD3E CD3E INPPL1 INPPL1 REM1 REM1 CBL CBL HCK HCK PLCG2 PLCG2 PTPN2 PTPN2 MATK MATK ENSPCOP00000012847 ENSPCOP00000012847 GRAP GRAP RRAS RRAS INPP5D INPP5D SHC2 SHC2 VAV1 VAV1 LAT LAT PIK3CA PIK3CA PIK3CG PIK3CG RALGPS2 RALGPS2 SH3KBP1 SH3KBP1 CD247 CD247 PIK3CB PIK3CB GRB10 GRB10 CD3G CD3G FCRL2 FCRL2 GRB14 GRB14 GRB2 GRB2 EGFR EGFR PIK3R2 PIK3R2 FGR FGR PIK3R1 PIK3R1 SRC SRC INSRR INSRR VAV3 VAV3 SHC3 SHC3 ENSPCOP00000019705 ENSPCOP00000019705 IRS2 IRS2 CBLC CBLC LCP2 LCP2 ZMAT3 ZMAT3 FCER1G FCER1G IGF1R IGF1R CBLB CBLB PTPN12 PTPN12 PIK3R5 PIK3R5 MST1R MST1R SRMS SRMS BLNK BLNK PLCG1 PLCG1 LYN LYN INSR INSR SH3GL1 SH3GL1 PIK3R6 PIK3R6 ZAP70 ZAP70 BMX BMX SPRY2 SPRY2 LRIG1 LRIG1 ERBB2 ERBB2 P3R3URF P3R3URF TXK TXK FCGR2B FCGR2B GP6 GP6 ENSPCOP00000029403 ENSPCOP00000029403 PTPN11 PTPN11 BTK BTK SH3GL2 SH3GL2 CD8B CD8B GRAP2 GRAP2 STAT3 STAT3 PIK3CD PIK3CD CSK CSK IGF2 IGF2 PDGFRB PDGFRB SHC1 SHC1 ITK ITK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DIRAS1DIRAS family GTPase 1. (198 aa)
ENSPCOP00000000722Protein kinase domain-containing protein. (67 aa)
PAG1Phosphoprotein membrane anchor with glycosphingolipid microdomains 1. (426 aa)
FRS3Fibroblast growth factor receptor substrate 3. (492 aa)
SLA2Src like adaptor 2. (269 aa)
SH3BP2SH3 domain binding protein 2. (612 aa)
CD3DUncharacterized protein. (97 aa)
OSCAROsteoclast associated Ig-like receptor. (266 aa)
TECTyrosine-protein kinase. (625 aa)
SH2D2ASH2 domain containing 2A. (378 aa)
SH3GL3SH3 domain containing GRB2 like 3, endophilin A3. (358 aa)
GRB7Growth factor receptor bound protein 7. (531 aa)
CD8ACD8a molecule. (239 aa)
SHC4SHC adaptor protein 4. (630 aa)
VAV2Vav guanine nucleotide exchange factor 2. (771 aa)
PIK3R3Uncharacterized protein. (454 aa)
FCGR2AUncharacterized protein. (307 aa)
LRIG3Leucine rich repeats and immunoglobulin like domains 3. (1120 aa)
CD4CD4 molecule. (452 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (435 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
SYKSpleen associated tyrosine kinase. (637 aa)
LOC105821782Uncharacterized protein. (380 aa)
LCKTyrosine-protein kinase. (417 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (882 aa)
FRKTyrosine-protein kinase. (508 aa)
NTRK1Tyrosine-protein kinase receptor. (796 aa)
PTPN18Protein tyrosine phosphatase non-receptor type 18. (336 aa)
CD3ECD3e molecule. (187 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1264 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (298 aa)
CBLCbl proto-oncogene. (891 aa)
HCKTyrosine-protein kinase. (524 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1233 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (415 aa)
MATKTyrosine-protein kinase. (507 aa)
ENSPCOP00000012847IG domain-containing protein. (167 aa)
GRAPGRB2 related adaptor protein. (217 aa)
RRASRAS related. (220 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1178 aa)
SHC2Uncharacterized protein. (578 aa)
VAV1Vav guanine nucleotide exchange factor 1. (806 aa)
LATLinker for activation of T cells. (236 aa)
PIK3CAPhosphatidylinositol 3-kinase catalytic subunit type 3. (933 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa)
RALGPS2Ral GEF with PH domain and SH3 binding motif 2. (514 aa)
SH3KBP1SH3 domain containing kinase binding protein 1. (708 aa)
CD247CD247 molecule. (164 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
GRB10Growth factor receptor bound protein 10. (595 aa)
CD3GCD3g molecule. (182 aa)
FCRL2Fc receptor like 2. (438 aa)
GRB14Growth factor receptor bound protein 14. (476 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
PIK3R2Uncharacterized protein. (726 aa)
FGRTyrosine-protein kinase. (495 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
SRCTyrosine-protein kinase. (543 aa)
INSRRTyrosine-protein kinase receptor. (1272 aa)
VAV3Vav guanine nucleotide exchange factor 3. (765 aa)
SHC3SHC adaptor protein 3. (596 aa)
ENSPCOP00000019705Uncharacterized protein. (583 aa)
IRS2Insulin receptor substrate 2. (1335 aa)
CBLCCbl proto-oncogene C. (458 aa)
LCP2Lymphocyte cytosolic protein 2. (493 aa)
ZMAT3Zinc finger matrin-type 3. (288 aa)
FCER1GFc fragment of IgE receptor Ig. (86 aa)
IGF1RTyrosine-protein kinase receptor. (1350 aa)
CBLBCbl proto-oncogene B. (908 aa)
PTPN12Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades. (705 aa)
PIK3R5Phosphoinositide-3-kinase regulatory subunit 5. (879 aa)
MST1RMacrophage stimulating 1 receptor. (1403 aa)
SRMSTyrosine-protein kinase. (496 aa)
BLNKB cell linker. (421 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1304 aa)
LYNTyrosine-protein kinase. (512 aa)
INSRInsulin receptor. (1192 aa)
SH3GL1SH3 domain containing GRB2 like 1, endophilin A2. (368 aa)
PIK3R6Phosphoinositide-3-kinase regulatory subunit 6. (756 aa)
ZAP70Tyrosine-protein kinase. (617 aa)
BMXTyrosine-protein kinase. (627 aa)
SPRY2Sprouty RTK signaling antagonist 2. (314 aa)
LRIG1Leucine rich repeats and immunoglobulin like domains 1. (1063 aa)
ERBB2Receptor protein-tyrosine kinase. (1252 aa)
P3R3URFPIK3R3 upstream reading frame. (95 aa)
TXKTyrosine-protein kinase. (581 aa)
FCGR2BUncharacterized protein. (316 aa)
GP6IG domain-containing protein. (287 aa)
ENSPCOP00000029403Protein kinase domain-containing protein. (429 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
BTKTyrosine-protein kinase. (647 aa)
SH3GL2SH3 domain containing GRB2 like 2, endophilin A1. (352 aa)
CD8BIg-like domain-containing protein. (210 aa)
GRAP2GRB2 related adaptor protein 2. (326 aa)
STAT3Signal transducer and activator of transcription. (796 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
CSKTyrosine-protein kinase. (450 aa)
IGF2Insulin like growth factor 2. (236 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1105 aa)
SHC1SHC adaptor protein 1. (582 aa)
ITKTyrosine-protein kinase. (598 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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