37 items (Propithecus coquereli) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

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co-expression

protein homology

Your Input:
	WRNIP1	WRN helicase interacting protein 1. (666 aa)
	POLA1	DNA polymerase. (1442 aa)
	USP43	Ubiquitin specific peptidase 43; Belongs to the peptidase C19 family. (1122 aa)
	CDKN2D	Cyclin dependent kinase inhibitor 2D. (166 aa)
	REV3L	REV3 like, DNA directed polymerase zeta catalytic subunit. (3120 aa)
	POLE	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2284 aa)
	POLD1	DNA polymerase. (1125 aa)
	RFC3	Replication factor C subunit 3. (356 aa)
	VCP	Valosin containing protein; Belongs to the AAA ATPase family. (806 aa)
	POLDIP2	DNA polymerase delta interacting protein 2. (368 aa)
	LOC105824103	Uncharacterized protein. (430 aa)
	POLI	DNA polymerase iota. (735 aa)
	DTL	Denticleless E3 ubiquitin protein ligase homolog. (784 aa)
	TEX12	Testis expressed 12. (123 aa)
	POLD4	Uncharacterized protein. (107 aa)
	POLD2	DNA polymerase delta 2, accessory subunit. (504 aa)
	POLD3	DNA polymerase delta 3, accessory subunit. (359 aa)
	RCHY1	Ring finger and CHY zinc finger domain containing 1. (231 aa)
	ZBTB1	Zinc finger and BTB domain containing 1. (653 aa)
	SPATA22	Spermatogenesis associated 22. (363 aa)
	SIRT1	Sirtuin 1. (743 aa)
	POLE2	DNA polymerase epsilon 2, accessory subunit. (439 aa)
	USP1	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (785 aa)
	POLK	DNA polymerase kappa. (832 aa)
	POLN	DNA polymerase nu. (899 aa)
	PARP10	Poly [ADP-ribose] polymerase. (985 aa)
	REV1	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1197 aa)
	HROB	Chromosome 17 open reading frame 53. (652 aa)
	SPRTN	Uncharacterized protein. (493 aa)
	PCLAF	PAF domain-containing protein. (65 aa)
	ENSPCOP00000007225	Uncharacterized protein. (492 aa)
	ENSPCOP00000008165	Uncharacterized protein. (177 aa)
	MAD2L2	Mitotic arrest deficient 2 like 2. (235 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	SYCP1	Synaptonemal complex protein 1. (767 aa)
	POLH	DNA polymerase eta. (709 aa)
	USP10	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (798 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDKN2D	VCP	ENSPCOP00000013590	ENSPCOP00000016734	Cyclin dependent kinase inhibitor 2D.	Valosin containing protein; Belongs to the AAA ATPase family.	0.437
DTL	LOC105824103	ENSPCOP00000022701	ENSPCOP00000019020	Denticleless E3 ubiquitin protein ligase homolog.	Uncharacterized protein.	0.653
DTL	PCLAF	ENSPCOP00000022701	ENSPCOP00000004804	Denticleless E3 ubiquitin protein ligase homolog.	PAF domain-containing protein.	0.807
DTL	PCNA	ENSPCOP00000022701	ENSPCOP00000008972	Denticleless E3 ubiquitin protein ligase homolog.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.994
DTL	POLA1	ENSPCOP00000022701	ENSPCOP00000012099	Denticleless E3 ubiquitin protein ligase homolog.	DNA polymerase.	0.791
DTL	POLD1	ENSPCOP00000022701	ENSPCOP00000015021	Denticleless E3 ubiquitin protein ligase homolog.	DNA polymerase.	0.790
DTL	POLD2	ENSPCOP00000022701	ENSPCOP00000023689	Denticleless E3 ubiquitin protein ligase homolog.	DNA polymerase delta 2, accessory subunit.	0.762
DTL	POLD3	ENSPCOP00000022701	ENSPCOP00000024678	Denticleless E3 ubiquitin protein ligase homolog.	DNA polymerase delta 3, accessory subunit.	0.653
DTL	POLD4	ENSPCOP00000022701	ENSPCOP00000023120	Denticleless E3 ubiquitin protein ligase homolog.	Uncharacterized protein.	0.615
DTL	POLE	ENSPCOP00000022701	ENSPCOP00000014601	Denticleless E3 ubiquitin protein ligase homolog.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.945
DTL	POLE2	ENSPCOP00000022701	ENSPCOP00000029196	Denticleless E3 ubiquitin protein ligase homolog.	DNA polymerase epsilon 2, accessory subunit.	0.856
DTL	REV3L	ENSPCOP00000022701	ENSPCOP00000014412	Denticleless E3 ubiquitin protein ligase homolog.	REV3 like, DNA directed polymerase zeta catalytic subunit.	0.734
DTL	RFC3	ENSPCOP00000022701	ENSPCOP00000015964	Denticleless E3 ubiquitin protein ligase homolog.	Replication factor C subunit 3.	0.870
DTL	USP1	ENSPCOP00000022701	ENSPCOP00000029558	Denticleless E3 ubiquitin protein ligase homolog.	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	0.733
ENSPCOP00000007225	PCNA	ENSPCOP00000007225	ENSPCOP00000008972	Uncharacterized protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.973
ENSPCOP00000007225	POLD1	ENSPCOP00000007225	ENSPCOP00000015021	Uncharacterized protein.	DNA polymerase.	0.532
ENSPCOP00000007225	POLH	ENSPCOP00000007225	ENSPCOP00000009689	Uncharacterized protein.	DNA polymerase eta.	0.776
ENSPCOP00000007225	POLI	ENSPCOP00000007225	ENSPCOP00000021093	Uncharacterized protein.	DNA polymerase iota.	0.728
ENSPCOP00000007225	POLK	ENSPCOP00000007225	ENSPCOP00000029619	Uncharacterized protein.	DNA polymerase kappa.	0.689
ENSPCOP00000007225	REV1	ENSPCOP00000007225	ENSPCOP00000004714	Uncharacterized protein.	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	0.694