14 items (Propithecus coquereli) - STRING interaction network

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Your Input:
	CTC1	CST telomere replication complex component 1. (1221 aa)
	TINF2	TERF1 interacting nuclear factor 2. (451 aa)
	ENSPCOP00000002776	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (330 aa)
	TERB1	Telomere repeat binding bouquet formation protein 1. (592 aa)
	POT1	Protection of telomeres 1. (600 aa)
	XRCC5	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (677 aa)
	LOC105817821	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (689 aa)
	STN1	CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (369 aa)
	TERF2	Telomeric repeat binding factor 2. (542 aa)
	TERF1	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (435 aa)
	ENSPCOP00000025432	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (747 aa)
	TEN1	Uncharacterized protein. (137 aa)
	XRCC6	X-ray repair cross complementing 6. (496 aa)
	ACD	ACD shelterin complex subunit and telomerase recruitment factor. (513 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACD	CTC1	ENSPCOP00000030285	ENSPCOP00000027978	ACD shelterin complex subunit and telomerase recruitment factor.	CST telomere replication complex component 1.	0.827
ACD	ENSPCOP00000002776	ENSPCOP00000030285	ENSPCOP00000002776	ACD shelterin complex subunit and telomerase recruitment factor.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	0.963
ACD	ENSPCOP00000025432	ENSPCOP00000030285	ENSPCOP00000025432	ACD shelterin complex subunit and telomerase recruitment factor.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	0.963
ACD	POT1	ENSPCOP00000030285	ENSPCOP00000004523	ACD shelterin complex subunit and telomerase recruitment factor.	Protection of telomeres 1.	0.998
ACD	STN1	ENSPCOP00000030285	ENSPCOP00000012196	ACD shelterin complex subunit and telomerase recruitment factor.	CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.	0.900
ACD	TEN1	ENSPCOP00000030285	ENSPCOP00000026041	ACD shelterin complex subunit and telomerase recruitment factor.	Uncharacterized protein.	0.792
ACD	TERF1	ENSPCOP00000030285	ENSPCOP00000020972	ACD shelterin complex subunit and telomerase recruitment factor.	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.	0.991
ACD	TERF2	ENSPCOP00000030285	ENSPCOP00000020164	ACD shelterin complex subunit and telomerase recruitment factor.	Telomeric repeat binding factor 2.	0.992
ACD	TINF2	ENSPCOP00000030285	ENSPCOP00000000492	ACD shelterin complex subunit and telomerase recruitment factor.	TERF1 interacting nuclear factor 2.	0.998
CTC1	ACD	ENSPCOP00000027978	ENSPCOP00000030285	CST telomere replication complex component 1.	ACD shelterin complex subunit and telomerase recruitment factor.	0.827
CTC1	POT1	ENSPCOP00000027978	ENSPCOP00000004523	CST telomere replication complex component 1.	Protection of telomeres 1.	0.921
CTC1	STN1	ENSPCOP00000027978	ENSPCOP00000012196	CST telomere replication complex component 1.	CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.	0.997
CTC1	TEN1	ENSPCOP00000027978	ENSPCOP00000026041	CST telomere replication complex component 1.	Uncharacterized protein.	0.997
CTC1	TERB1	ENSPCOP00000027978	ENSPCOP00000004278	CST telomere replication complex component 1.	Telomere repeat binding bouquet formation protein 1.	0.606
CTC1	TERF1	ENSPCOP00000027978	ENSPCOP00000020972	CST telomere replication complex component 1.	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.	0.861
CTC1	TERF2	ENSPCOP00000027978	ENSPCOP00000020164	CST telomere replication complex component 1.	Telomeric repeat binding factor 2.	0.806
CTC1	TINF2	ENSPCOP00000027978	ENSPCOP00000000492	CST telomere replication complex component 1.	TERF1 interacting nuclear factor 2.	0.894
ENSPCOP00000002776	ACD	ENSPCOP00000002776	ENSPCOP00000030285	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	ACD shelterin complex subunit and telomerase recruitment factor.	0.963
ENSPCOP00000002776	ENSPCOP00000025432	ENSPCOP00000002776	ENSPCOP00000025432	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	0.942
ENSPCOP00000002776	LOC105817821	ENSPCOP00000002776	ENSPCOP00000009690	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.	0.838