STRINGSTRING
HNF1A HNF1A RELA RELA AR AR PPARD PPARD THRB THRB GATA6 GATA6 ENSPCOP00000025432 ENSPCOP00000025432 SMAD4 SMAD4 CCNT2 CCNT2 RARA RARA CDK9 CDK9 ESR1 ESR1 RORA RORA TFAM TFAM SMAD3 SMAD3 CREBBP CREBBP GATA1 GATA1 EP300 EP300 CIT CIT ATF7 ATF7 PPARA PPARA ZBTB49 ZBTB49 VGLL4 VGLL4 GATA3 GATA3 NFKB1 NFKB1 STAT1 STAT1 TRERF1 TRERF1 MED25 MED25 EPAS1 EPAS1 MED1 MED1 HIF1A HIF1A TEAD2 TEAD2 ENSPCOP00000002776 ENSPCOP00000002776 HAND2 HAND2 GATA2 GATA2 ZBTB17 ZBTB17 NFATC1 NFATC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HNF1AHNF1 homeobox A. (662 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
ARAndrogen receptor. (886 aa)
PPARDPeroxisome proliferator activated receptor delta. (440 aa)
THRBThyroid hormone receptor beta. (476 aa)
GATA6GATA binding protein 6. (593 aa)
ENSPCOP00000025432Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (747 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (733 aa)
RARARetinoic acid receptor alpha. (472 aa)
CDK9Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (599 aa)
RORARAR related orphan receptor A. (532 aa)
TFAMTranscription factor A, mitochondrial. (246 aa)
SMAD3Mothers against decapentaplegic homolog. (443 aa)
CREBBPCREB binding protein. (2449 aa)
GATA1GATA binding protein 1. (413 aa)
EP300E1A binding protein p300. (2424 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2040 aa)
ATF7Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (483 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
ZBTB49Zinc finger and BTB domain containing 49. (763 aa)
VGLL4Vestigial like family member 4. (296 aa)
GATA3Uncharacterized protein. (444 aa)
NFKB1Nuclear factor kappa B subunit 1. (961 aa)
STAT1Signal transducer and activator of transcription. (794 aa)
TRERF1Transcriptional regulating factor 1. (1154 aa)
MED25Mediator complex subunit 25. (754 aa)
EPAS1Endothelial PAS domain protein 1. (869 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1583 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (826 aa)
TEAD2TEA domain transcription factor 2. (449 aa)
ENSPCOP00000002776Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (330 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
GATA2GATA binding protein 2. (445 aa)
ZBTB17Zinc finger and BTB domain containing 17. (798 aa)
NFATC1Nuclear factor of activated T cells 1. (945 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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