STRINGSTRING
EIF2B5 EIF2B5 ENSPCOP00000004143 ENSPCOP00000004143 KDR KDR MMP19 MMP19 MMP2 MMP2 EIF2B2 EIF2B2 ENSPCOP00000012404 ENSPCOP00000012404 TNFAIP6 TNFAIP6 GAS2 GAS2 FSHB FSHB INHBB INHBB BMPR1B BMPR1B LFNG LFNG SOD1 SOD1 ATM ATM UBE3A UBE3A INHA INHA EIF2B4 EIF2B4 SRC SRC INHBA INHBA BAX BAX DMRTA1 DMRTA1 FSHR FSHR SPO11 SPO11 BCL2L1 BCL2L1 BCL2 BCL2 LHCGR LHCGR FANCG FANCG KITLG KITLG EREG EREG ESR1 ESR1 PCYT1B PCYT1B KIT KIT VEGFA VEGFA IMMP2L IMMP2L SMAD4 SMAD4 PTX3 PTX3 DMC1 DMC1 CEBPB CEBPB FOXC1 FOXC1 AMH AMH GPR149 GPR149 SCAPER SCAPER TAF4 TAF4 CTNNA1 CTNNA1 MSH4 MSH4 ENSPCOP00000030811 ENSPCOP00000030811
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EIF2B5Eukaryotic translation initiation factor 2B subunit epsilon. (722 aa)
ENSPCOP00000004143Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (136 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
MMP19Matrix metallopeptidase 19. (508 aa)
MMP2Matrix metallopeptidase 2. (552 aa)
EIF2B2Eukaryotic translation initiation factor 2B subunit beta; Belongs to the eIF-2B alpha/beta/delta subunits family. (351 aa)
ENSPCOP00000012404Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (125 aa)
TNFAIP6TNF alpha induced protein 6. (262 aa)
GAS2Growth arrest specific 2. (314 aa)
FSHBFollicle stimulating hormone subunit beta. (129 aa)
INHBBInhibin subunit beta B. (408 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (500 aa)
LFNGBeta-1,3-N-acetylglucosaminyltransferase. (377 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (153 aa)
ATMATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2635 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (870 aa)
INHAInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (368 aa)
EIF2B4Eukaryotic translation initiation factor 2B subunit delta; Belongs to the eIF-2B alpha/beta/delta subunits family. (524 aa)
SRCTyrosine-protein kinase. (543 aa)
INHBAInhibin subunit beta A. (426 aa)
BAXBCL2 associated X, apoptosis regulator. (199 aa)
DMRTA1DMRT like family A1. (502 aa)
FSHRFollicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (695 aa)
SPO11SPO11 initiator of meiotic double stranded breaks. (285 aa)
BCL2L1BCL2 like 1. (233 aa)
BCL2BCL2 apoptosis regulator. (234 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (701 aa)
FANCGFA complementation group G. (621 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
EREGEpiregulin. (166 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (599 aa)
PCYT1BPhosphate cytidylyltransferase 1, choline, beta. (369 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (395 aa)
IMMP2LMitochondrial inner membrane protease subunit. (175 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
PTX3Pentraxin 3. (382 aa)
DMC1Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (325 aa)
CEBPBCCAAT/enhancer-binding protein. (347 aa)
FOXC1Forkhead box C1. (535 aa)
AMHAnti-Mullerian hormone. (561 aa)
GPR149G protein-coupled receptor 149. (733 aa)
SCAPERS-phase cyclin A associated protein in the ER. (1400 aa)
TAF4TATA-box binding protein associated factor 4. (636 aa)
CTNNA1Catenin alpha 1. (906 aa)
MSH4MutS homolog 4. (834 aa)
ENSPCOP00000030811Sod_Cu domain-containing protein. (132 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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