41 items (Propithecus coquereli) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	WNT9B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
	PTCH1	Patched 1. (1449 aa)
	GDNF	Glial cell derived neurotrophic factor. (228 aa)
	WNT4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	BCL2	BCL2 apoptosis regulator. (234 aa)
	LHX1	LIM homeobox 1. (406 aa)
	ENSPCOP00000018033	HH_signal domain-containing protein. (110 aa)
	WT1	WT1 transcription factor. (522 aa)
	CTNNBIP1	Catenin beta interacting protein 1. (81 aa)
	PAX2	Paired box 2. (417 aa)
	LAMA5	Laminin subunit alpha 5. (3694 aa)
	FGF1	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
	WNT6	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
	FGF8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
	HS3ST3A1	Sulfotransferase; Belongs to the sulfotransferase 1 family. (406 aa)
	HOXA11	Homeobox A11. (316 aa)
	GLI3	GLI family zinc finger 3. (1580 aa)
	GREB1L	GREB1 like retinoic acid receptor coactivator. (1781 aa)
	DLG1	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (910 aa)
	TCF21	Transcription factor 21. (179 aa)
	LHX5	LIM homeobox 5. (402 aa)
	FGF2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (394 aa)
	SALL1	Spalt like transcription factor 1. (1315 aa)
	BMP2	Bone morphogenetic protein 2. (395 aa)
	PKD2	Polycystin 2, transient receptor potential cation channel. (963 aa)
	SOX9	SRY-box transcription factor 9. (505 aa)
	HS3ST3B1	Sulfotransferase; Belongs to the sulfotransferase 1 family. (390 aa)
	FOXD1	Forkhead box D1. (467 aa)
	GREB1	Growth regulating estrogen receptor binding 1. (1891 aa)
	CITED1	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (221 aa)
	HOXD11	Homeobox D11. (339 aa)
	ADAMTS16	ADAM metallopeptidase with thrombospondin type 1 motif 16. (1209 aa)
	WNT1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
	EYA1	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
	SIX1	SIX homeobox 1. (284 aa)
	PGF	Placental growth factor; Belongs to the PDGF/VEGF growth factor family. (220 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	TMEM59L	Transmembrane protein 59 like. (343 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	GZF1	GDNF inducible zinc finger protein 1. (710 aa)
	CTNNB1	Catenin beta 1. (781 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL2	CTNNB1	ENSPCOP00000020794	ENSPCOP00000022753	BCL2 apoptosis regulator.	Catenin beta 1.	0.520
BMP2	BMP4	ENSPCOP00000030823	ENSPCOP00000028335	Bone morphogenetic protein 2.	Bone morphogenetic protein 4.	0.896
BMP2	CTNNB1	ENSPCOP00000030823	ENSPCOP00000022753	Bone morphogenetic protein 2.	Catenin beta 1.	0.469
BMP2	ENSPCOP00000018033	ENSPCOP00000030823	ENSPCOP00000018033	Bone morphogenetic protein 2.	HH_signal domain-containing protein.	0.538
BMP2	FGF2	ENSPCOP00000030823	ENSPCOP00000031028	Bone morphogenetic protein 2.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.562
BMP2	FGF8	ENSPCOP00000030823	ENSPCOP00000012774	Bone morphogenetic protein 2.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.455
BMP2	PTCH1	ENSPCOP00000030823	ENSPCOP00000022438	Bone morphogenetic protein 2.	Patched 1.	0.569
BMP2	SMAD4	ENSPCOP00000030823	ENSPCOP00000024999	Bone morphogenetic protein 2.	Mothers against decapentaplegic homolog.	0.923
BMP2	SOX9	ENSPCOP00000030823	ENSPCOP00000029276	Bone morphogenetic protein 2.	SRY-box transcription factor 9.	0.454
BMP4	BMP2	ENSPCOP00000028335	ENSPCOP00000030823	Bone morphogenetic protein 4.	Bone morphogenetic protein 2.	0.896
BMP4	CTNNB1	ENSPCOP00000028335	ENSPCOP00000022753	Bone morphogenetic protein 4.	Catenin beta 1.	0.472
BMP4	ENSPCOP00000018033	ENSPCOP00000028335	ENSPCOP00000018033	Bone morphogenetic protein 4.	HH_signal domain-containing protein.	0.640
BMP4	FGF2	ENSPCOP00000028335	ENSPCOP00000031028	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.501
BMP4	FGF8	ENSPCOP00000028335	ENSPCOP00000012774	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.470
BMP4	PTCH1	ENSPCOP00000028335	ENSPCOP00000022438	Bone morphogenetic protein 4.	Patched 1.	0.569
BMP4	SMAD4	ENSPCOP00000028335	ENSPCOP00000024999	Bone morphogenetic protein 4.	Mothers against decapentaplegic homolog.	0.932
CITED1	FOXD1	ENSPCOP00000005392	ENSPCOP00000004101	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1.	Forkhead box D1.	0.402
CITED1	LHX1	ENSPCOP00000005392	ENSPCOP00000018048	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1.	LIM homeobox 1.	0.418
CITED1	SMAD4	ENSPCOP00000005392	ENSPCOP00000024999	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1.	Mothers against decapentaplegic homolog.	0.431
CTNNB1	BCL2	ENSPCOP00000022753	ENSPCOP00000020794	Catenin beta 1.	BCL2 apoptosis regulator.	0.520