STRINGSTRING
TGFB3 TGFB3 FAM167A FAM167A LOXL2 LOXL2 ZFP36L1 ZFP36L1 ENG ENG P2RX2 P2RX2 RBPJ RBPJ PLAT PLAT CYGB CYGB EGLN3 EGLN3 NARF NARF MYC MYC MT3 MT3 SUV39H2 SUV39H2 PDK1 PDK1 TIGAR TIGAR PMAIP1 PMAIP1 ENSPCOP00000002776 ENSPCOP00000002776 EPO EPO NFE2L2 NFE2L2 NOL3 NOL3 ENSPCOP00000002148 ENSPCOP00000002148 SLC2A1 SLC2A1 CYBB CYBB BCL2 BCL2 PDK3 PDK3 PENK PENK PML PML SRF SRF ENSPCOP00000019967 ENSPCOP00000019967 FOS FOS ALKBH5 ALKBH5 PLEKHN1 PLEKHN1 TXN2 TXN2 NOS1 NOS1 EP300 EP300 LOC105815021 LOC105815021 DDIT4 DDIT4 KCNMB1 KCNMB1 DDR2 DDR2 SRC SRC ADA ADA ADAM8 ADAM8 E2F1 E2F1 ANGPT2 ANGPT2 NPPC NPPC MGARP MGARP CHRNB2 CHRNB2 ATM ATM APAF1 APAF1 VCAM1 VCAM1 MMP2 MMP2 VEGFB VEGFB TGFBR3 TGFBR3 RGCC RGCC ENSPCOP00000008878 ENSPCOP00000008878 TM9SF4 TM9SF4 AQP1 AQP1 PTGS2 PTGS2 NOP53 NOP53 BBC3 BBC3 PAM PAM MLST8 MLST8 AJUBA AJUBA CASR CASR SLC2A8 SLC2A8 RPTOR RPTOR STC1 STC1 BNIP3 BNIP3 SLC8A3 SLC8A3 WDR83 WDR83 VHL VHL HIF1AN HIF1AN ENSPCOP00000014340 ENSPCOP00000014340 P4HB P4HB OPRD1 OPRD1 NDRG1 NDRG1 HSF1 HSF1 UCP3 UCP3 LONP1 LONP1 SLC2A4 SLC2A4 ENSPCOP00000013232 ENSPCOP00000013232 ADIPOQ ADIPOQ SLC11A2 SLC11A2 STOX1 STOX1 RYR1 RYR1 CHRNA4 CHRNA4 SLC8A1 SLC8A1 HK2 HK2 TREM2 TREM2 ABAT ABAT PGF PGF ANGPT4 ANGPT4 PIN1 PIN1 CA9 CA9 PPARA PPARA SIRT2 SIRT2 ENSPCOP00000011649 ENSPCOP00000011649 FUNDC1 FUNDC1 CPEB1 CPEB1 RYR2 RYR2 ANGPTL4 ANGPTL4 ENSPCOP00000003708 ENSPCOP00000003708 BMP7 BMP7 ENSPCOP00000003784 ENSPCOP00000003784 HIPK2 HIPK2 ITPR2 ITPR2 HMOX1 HMOX1 CAV3 CAV3 HYOU1 HYOU1 NOTCH1 NOTCH1 HIF1A HIF1A FABP1 FABP1 ANG ANG WTIP WTIP ENSPCOP00000005309 ENSPCOP00000005309 ERO1A ERO1A EPAS1 EPAS1 CCNA2 CCNA2 JUND JUND ENSPCOP00000006354 ENSPCOP00000006354 PLOD2 PLOD2 CXCL12 CXCL12 ENSPCOP00000006834 ENSPCOP00000006834 IRAK1 IRAK1 USF1 USF1 MTOR MTOR ENSPCOP00000001518 ENSPCOP00000001518 PTEN PTEN MST1 MST1 SIRT4 SIRT4 TGFBR2 TGFBR2 TGFB2 TGFB2 FNDC1 FNDC1 ALAS2 ALAS2 EGR1 EGR1 KCNK2 KCNK2 AGER AGER STUB1 STUB1 EDN1 EDN1 HMOX2 HMOX2 SLC29A1 SLC29A1 ENSPCOP00000028966 ENSPCOP00000028966 CPEB2 CPEB2 UCP2 UCP2 SCAP SCAP SLC9A1 SLC9A1 TP53 TP53 VEGFD VEGFD CBFA2T3 CBFA2T3 DPP4 DPP4 CIAO3 CIAO3 ENSPCOP00000031233 ENSPCOP00000031233 ARNT ARNT MYOCD MYOCD LMNA LMNA PKLR PKLR EDNRA EDNRA KCNK3 KCNK3 BMP2 BMP2 PPARD PPARD BAD BAD SFRP1 SFRP1 ADAM17 ADAM17 CREBBP CREBBP VEGFC VEGFC HIF3A HIF3A BACH1 BACH1 ENSPCOP00000021800 ENSPCOP00000021800 CITED2 CITED2 SMAD3 SMAD3 AQP3 AQP3 PTGIS PTGIS CAMK2G CAMK2G NGB NGB ATP7A ATP7A NR4A2 NR4A2 RORA RORA TGFB1 TGFB1 CHRNA7 CHRNA7 FAM162A FAM162A VEGFA VEGFA ADM ADM CYBA CYBA PDLIM1 PDLIM1 ENSPCOP00000024369 ENSPCOP00000024369 MDM4 MDM4 ENSPCOP00000024480 ENSPCOP00000024480 LIMD1 LIMD1 PINK1 PINK1 TH TH THBS1 THBS1 PDGFA PDGFA SMAD4 SMAD4 ADAM15 ADAM15 CAV1 CAV1 KCNMA1 KCNMA1 DIO3 DIO3 MECP2 MECP2 ITPR1 ITPR1 ENSPCOP00000025432 ENSPCOP00000025432 NKX3-1 NKX3-1 MPL MPL AK4 AK4 DNMT3A DNMT3A ENSPCOP00000025841 ENSPCOP00000025841 HSD11B2 HSD11B2 HSP90B1 HSP90B1 ATF2 ATF2 PRKCE PRKCE NF1 NF1 SCFD1 SCFD1 HP1BP3 HP1BP3 REST REST P2RX3 P2RX3 EGLN1 EGLN1 ITGA2 ITGA2 PLAU PLAU EGLN2 EGLN2 BNIP3L BNIP3L RTN4 RTN4 TBL2 TBL2 GATA6 GATA6 ENSPCOP00000027819 ENSPCOP00000027819 ARNT2 ARNT2 CDKN1B CDKN1B PTK2B PTK2B SIRT1 SIRT1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
FAM167AFamily with sequence similarity 167 member A. (217 aa)
LOXL2Lysyl oxidase like 2. (775 aa)
ZFP36L1ZFP36 ring finger protein like 1. (338 aa)
ENGEndoglin. (657 aa)
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (473 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (523 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (563 aa)
CYGBCytoglobin; Belongs to the globin family. (219 aa)
EGLN3Fe2OG dioxygenase domain-containing protein. (239 aa)
NARFNuclear prelamin A recognition factor; Belongs to the NARF family. (476 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (453 aa)
MT3Metallothionein 3; Belongs to the metallothionein superfamily. Type 1 family. (114 aa)
SUV39H2Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (410 aa)
PDK1Protein-serine/threonine kinase. (438 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (270 aa)
PMAIP1Uncharacterized protein. (54 aa)
ENSPCOP00000002776Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (330 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (194 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (606 aa)
NOL3Nucleolar protein 3. (204 aa)
ENSPCOP00000002148Uncharacterized protein. (118 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (495 aa)
CYBBCytochrome b-245 beta chain. (533 aa)
BCL2BCL2 apoptosis regulator. (234 aa)
PDK3Protein-serine/threonine kinase. (352 aa)
PENKProenkephalin. (267 aa)
PMLPromyelocytic leukemia. (887 aa)
SRFSerum response factor. (508 aa)
ENSPCOP00000019967Uncharacterized protein. (713 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (381 aa)
ALKBH5AlkB homolog 5, RNA demethylase. (394 aa)
PLEKHN1Pleckstrin homology domain containing N1. (643 aa)
TXN2Thioredoxin 2. (166 aa)
NOS1Nitric oxide synthase; Produces nitric oxide (NO). (1434 aa)
EP300E1A binding protein p300. (2424 aa)
LOC105815021Uncharacterized protein. (567 aa)
DDIT4DNA damage inducible transcript 4. (230 aa)
KCNMB1Potassium calcium-activated channel subfamily M regulatory beta subunit 1. (191 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (855 aa)
SRCTyrosine-protein kinase. (543 aa)
ADAAdenosine deaminase. (363 aa)
ADAM8ADAM metallopeptidase domain 8. (812 aa)
E2F1E2F transcription factor 1. (436 aa)
ANGPT2Angiopoietin 2. (496 aa)
NPPCNatriuretic peptide C. (126 aa)
MGARPMitochondria localized glutamic acid rich protein. (240 aa)
CHRNB2Cholinergic receptor nicotinic beta 2 subunit. (502 aa)
ATMATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2635 aa)
APAF1Apoptotic peptidase activating factor 1. (1204 aa)
VCAM1Vascular cell adhesion molecule 1. (739 aa)
MMP2Matrix metallopeptidase 2. (552 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (188 aa)
TGFBR3Transforming growth factor beta receptor 3. (851 aa)
RGCCRegulator of cell cycle. (137 aa)
ENSPCOP00000008878Uncharacterized protein. (329 aa)
TM9SF4Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (664 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
NOP53Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (417 aa)
BBC3BCL2 binding component 3. (260 aa)
PAMPeptidylglycine alpha-amidating monooxygenase. (695 aa)
MLST8MTOR associated protein, LST8 homolog. (326 aa)
AJUBAAjuba LIM protein. (539 aa)
CASRCalcium sensing receptor. (1076 aa)
SLC2A8Solute carrier family 2 member 8; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (448 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1281 aa)
STC1Stanniocalcin 1. (247 aa)
BNIP3Uncharacterized protein. (235 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (927 aa)
WDR83WD repeat domain 83. (315 aa)
VHLVon Hippel-Lindau tumor suppressor. (208 aa)
HIF1ANHypoxia inducible factor 1 subunit alpha inhibitor. (349 aa)
ENSPCOP00000014340Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (468 aa)
P4HBProtein disulfide-isomerase. (510 aa)
OPRD1Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (372 aa)
NDRG1N-myc downstream regulated 1. (373 aa)
HSF1Heat shock transcription factor 1. (531 aa)
UCP3Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. (311 aa)
LONP1Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...] (960 aa)
SLC2A4Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
ENSPCOP00000013232Protein-serine/threonine kinase. (359 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (244 aa)
SLC11A2Uncharacterized protein. (590 aa)
STOX1Storkhead box 1. (980 aa)
RYR1Ryanodine receptor 1. (4928 aa)
CHRNA4Cholinergic receptor nicotinic alpha 4 subunit. (623 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (974 aa)
HK2Hexokinase 2. (841 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (224 aa)
ABAT4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (500 aa)
PGFPlacental growth factor; Belongs to the PDGF/VEGF growth factor family. (220 aa)
ANGPT4Angiopoietin 4. (499 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (163 aa)
CA9Carbonic anhydrase 9; Belongs to the alpha-carbonic anhydrase family. (447 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
SIRT2Sirtuin 2. (469 aa)
ENSPCOP00000011649Peptidase_M1 domain-containing protein. (151 aa)
FUNDC1FUN14 domain containing 1. (155 aa)
CPEB1Uncharacterized protein. (589 aa)
RYR2Ryanodine receptor 2. (4825 aa)
ANGPTL4Angiopoietin like 4. (411 aa)
ENSPCOP00000003708Uncharacterized protein. (135 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
ENSPCOP00000003784Na_trans_assoc domain-containing protein. (129 aa)
HIPK2Homeodomain interacting protein kinase 2. (1187 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2702 aa)
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
HYOU1Hypoxia up-regulated 1. (997 aa)
NOTCH1Notch receptor 1. (2420 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (826 aa)
FABP1FABP domain-containing protein. (69 aa)
ANGAngiogenin; Belongs to the pancreatic ribonuclease family. (146 aa)
WTIPWT1 interacting protein. (299 aa)
ENSPCOP00000005309Fe2OG dioxygenase domain-containing protein. (121 aa)
ERO1AEndoplasmic reticulum oxidoreductase 1 alpha. (385 aa)
EPAS1Endothelial PAS domain protein 1. (869 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (432 aa)
JUNDJunD proto-oncogene, AP-1 transcription factor subunit. (348 aa)
ENSPCOP00000006354ERAP1_C domain-containing protein. (413 aa)
PLOD2Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2. (505 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (159 aa)
ENSPCOP00000006834Uncharacterized protein. (78 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (713 aa)
USF1Upstream transcription factor 1. (310 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2536 aa)
ENSPCOP00000001518TAFH domain-containing protein. (268 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
MST1Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. (725 aa)
SIRT4NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (314 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
FNDC1Fibronectin type III domain containing 1. (1868 aa)
ALAS25-aminolevulinate synthase. (587 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (543 aa)
KCNK2Potassium two pore domain channel subfamily K member 2. (371 aa)
AGERAdvanced glycosylation end-product specific receptor. (403 aa)
STUB1STIP1 homology and U-box containing protein 1. (304 aa)
EDN1Endothelin 1. (193 aa)
HMOX2Heme oxygenase 2. (328 aa)
SLC29A1Solute carrier family 29 member 1 (Augustine blood group). (456 aa)
ENSPCOP00000028966Uncharacterized protein. (188 aa)
CPEB2Cytoplasmic polyadenylation element binding protein 2. (937 aa)
UCP2Uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (309 aa)
SCAPSREBF chaperone. (1281 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (385 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (319 aa)
CBFA2T3CBFA2/RUNX1 partner transcriptional co-repressor 3. (573 aa)
DPP4Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (766 aa)
CIAO3Cytosolic iron-sulfur assembly component 3; Belongs to the NARF family. (476 aa)
ENSPCOP00000031233Uncharacterized protein. (318 aa)
ARNTAryl hydrocarbon receptor nuclear translocator. (748 aa)
MYOCDMyocardin. (780 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (665 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (574 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
KCNK3Potassium channel subfamily K member. (394 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
PPARDPeroxisome proliferator activated receptor delta. (440 aa)
BADBCL2 associated agonist of cell death. (168 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
ADAM17ADAM metallopeptidase domain 17. (757 aa)
CREBBPCREB binding protein. (2449 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (367 aa)
HIF3AHypoxia inducible factor 3 subunit alpha. (669 aa)
BACH1BTB domain and CNC homolog 1. (737 aa)
ENSPCOP00000021800Uncharacterized protein. (175 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (273 aa)
SMAD3Mothers against decapentaplegic homolog. (443 aa)
AQP3Aquaporin 3 (Gill blood group); Belongs to the MIP/aquaporin (TC 1.A.8) family. (292 aa)
PTGISProstacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (500 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (600 aa)
NGBNeuroglobin; Belongs to the globin family. (151 aa)
ATP7AATPase copper transporting alpha. (1502 aa)
NR4A2Nuclear receptor subfamily 4 group A member 2. (598 aa)
RORARAR related orphan receptor A. (532 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
CHRNA7Uncharacterized protein. (531 aa)
FAM162AFamily with sequence similarity 162 member A. (155 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (395 aa)
ADMAdrenomedullin. (182 aa)
CYBACytochrome b-245 alpha chain. (129 aa)
PDLIM1PDZ and LIM domain 1. (329 aa)
ENSPCOP00000024369Uncharacterized protein; Belongs to the intermediate filament family. (156 aa)
MDM4Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (491 aa)
ENSPCOP00000024480Uncharacterized protein. (103 aa)
LIMD1LIM domains containing 1. (672 aa)
PINK1PTEN induced kinase 1. (581 aa)
THTyrosine hydroxylase. (497 aa)
THBS1Thrombospondin 1. (1185 aa)
PDGFAPlatelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
ADAM15ADAM metallopeptidase domain 15. (859 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1286 aa)
DIO3Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). (288 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (500 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2732 aa)
ENSPCOP00000025432Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (747 aa)
NKX3-1NK3 homeobox 1. (226 aa)
MPLMPL proto-oncogene, thrombopoietin receptor. (634 aa)
AK4Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. (223 aa)
DNMT3ADNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (912 aa)
ENSPCOP00000025841Uncharacterized protein; Belongs to the adenylate kinase family. (171 aa)
HSD11B2Hydroxysteroid 11-beta dehydrogenase 2. (329 aa)
HSP90B1HATPase_c domain-containing protein. (793 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
NF1Neurofibromin 1. (2841 aa)
SCFD1Sec1 family domain containing 1; Belongs to the STXBP/unc-18/SEC1 family. (942 aa)
HP1BP3Heterochromatin protein 1 binding protein 3. (499 aa)
RESTUncharacterized protein. (1018 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (397 aa)
EGLN1Uncharacterized protein. (427 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1129 aa)
PLAUPlasminogen activator, urokinase. (432 aa)
EGLN2Egl-9 family hypoxia inducible factor 2. (405 aa)
BNIP3LBCL2 interacting protein 3 like. (219 aa)
RTN4Reticulon. (1195 aa)
TBL2Transducin beta like 2. (446 aa)
GATA6GATA binding protein 6. (593 aa)
ENSPCOP00000027819Uncharacterized protein. (200 aa)
ARNT2Aryl hydrocarbon receptor nuclear translocator 2. (717 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (967 aa)
SIRT1Sirtuin 1. (743 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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