26 items (Propithecus coquereli) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EPHA2	EPH receptor A2. (976 aa)
	ENSPCOP00000031789	Uncharacterized protein. (227 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	CAV2	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
	FGF7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
	NF1	Neurofibromin 1. (2841 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
	VEGFA	Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (395 aa)
	BMPER	BMP binding endothelial regulator. (704 aa)
	PROK2	Prokineticin 2. (129 aa)
	ERN1	Endoplasmic reticulum to nucleus signaling 1. (935 aa)
	ITGB1BP1	Integrin subunit beta 1 binding protein 1. (200 aa)
	ENSPCOP00000022475	Uncharacterized protein. (173 aa)
	LOXL2	Lysyl oxidase like 2. (775 aa)
	PROK1	Prokineticin 1. (105 aa)
	TGFBR1	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (421 aa)
	PIK3CB	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
	BMPR2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1037 aa)
	DLG1	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (910 aa)
	TEK	TEK receptor tyrosine kinase. (1125 aa)
	SCARB1	Scavenger receptor class B member 1; Belongs to the CD36 family. (461 aa)
	VSTM4	V-set and transmembrane domain containing 4. (309 aa)
	THAP1	THAP domain containing 1. (213 aa)
	XBP1	BZIP domain-containing protein. (377 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	NRARP	NOTCH regulated ankyrin repeat protein. (114 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	BMPER	ENSPCOP00000028335	ENSPCOP00000024109	Bone morphogenetic protein 4.	BMP binding endothelial regulator.	0.695
BMP4	BMPR2	ENSPCOP00000028335	ENSPCOP00000015238	Bone morphogenetic protein 4.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.975
BMP4	FGF10	ENSPCOP00000028335	ENSPCOP00000001047	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.517
BMP4	FGF7	ENSPCOP00000028335	ENSPCOP00000026354	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.408
BMP4	TGFBR1	ENSPCOP00000028335	ENSPCOP00000018681	Bone morphogenetic protein 4.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.881
BMPER	BMP4	ENSPCOP00000024109	ENSPCOP00000028335	BMP binding endothelial regulator.	Bone morphogenetic protein 4.	0.695
BMPER	BMPR2	ENSPCOP00000024109	ENSPCOP00000015238	BMP binding endothelial regulator.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.574
BMPR2	BMP4	ENSPCOP00000015238	ENSPCOP00000028335	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Bone morphogenetic protein 4.	0.975
BMPR2	BMPER	ENSPCOP00000015238	ENSPCOP00000024109	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	BMP binding endothelial regulator.	0.574
BMPR2	CAV1	ENSPCOP00000015238	ENSPCOP00000025045	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.410
BMPR2	TGFBR1	ENSPCOP00000015238	ENSPCOP00000018681	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.881
CAV1	BMPR2	ENSPCOP00000025045	ENSPCOP00000015238	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.410
CAV1	CAV2	ENSPCOP00000025045	ENSPCOP00000026838	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.997
CAV1	EPHA2	ENSPCOP00000025045	ENSPCOP00000010318	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	EPH receptor A2.	0.557
CAV1	PIK3CB	ENSPCOP00000025045	ENSPCOP00000016466	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.401
CAV1	TGFBR1	ENSPCOP00000025045	ENSPCOP00000018681	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.434
CAV2	CAV1	ENSPCOP00000026838	ENSPCOP00000025045	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.997
ENSPCOP00000031789	TEK	ENSPCOP00000031789	ENSPCOP00000008595	Uncharacterized protein.	TEK receptor tyrosine kinase.	0.492
EPHA2	CAV1	ENSPCOP00000010318	ENSPCOP00000025045	EPH receptor A2.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.557
EPHA2	FGF10	ENSPCOP00000010318	ENSPCOP00000001047	EPH receptor A2.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.846