38 items (Propithecus coquereli) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

Your Input:
	XDH	Xanthine dehydrogenase. (1313 aa)
	PTPRM	Protein tyrosine phosphatase receptor type M. (1440 aa)
	MEF2C	Myocyte enhancer factor 2C. (483 aa)
	COL4A3	Collagen type IV alpha 3 chain. (1545 aa)
	ALOX5	Arachidonate 5-lipoxygenase. (675 aa)
	TNF	Tumor necrosis factor; Belongs to the tumor necrosis factor family. (235 aa)
	NGFR	Nerve growth factor receptor. (429 aa)
	CNMD	Chondromodulin. (287 aa)
	IL12B	Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (326 aa)
	ATP5F1A	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (571 aa)
	APOE	Apolipoprotein E. (314 aa)
	FLT1	Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa)
	RGCC	Regulator of cell cycle. (137 aa)
	IL12A	Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa)
	SPARC	Secreted protein acidic and cysteine rich. (303 aa)
	ATOH8	Atonal bHLH transcription factor 8. (313 aa)
	KRIT1	ANK_REP_REGION domain-containing protein. (723 aa)
	ACVRL1	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
	THBS1	Thrombospondin 1. (1185 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
	TNMD	Tenomodulin. (320 aa)
	NF1	Neurofibromin 1. (2841 aa)
	CAV2	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
	GHRL	Ghrelin and obestatin prepropeptide. (116 aa)
	SYNJ2BP	Synaptojanin 2 binding protein. (134 aa)
	GDF2	Growth differentiation factor 2. (427 aa)
	PDCD10	Programmed cell death 10. (186 aa)
	ATP5IF1	ATP synthase inhibitory factor subunit 1. (106 aa)
	VASH1	Vasohibin 1. (363 aa)
	ENG	Endoglin. (657 aa)
	TGFBR1	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (421 aa)
	PRL	Prolactin. (231 aa)
	AIMP1	Aminoacyl tRNA synthetase complex interacting multifunctional protein 1. (283 aa)
	SULF1	Sulfatase 1. (863 aa)
	MMRN2	Multimerin 2. (948 aa)
	DLL4	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
	TBC1D31	TBC1 domain family member 31. (1062 aa)
	STAT1	Signal transducer and activator of transcription. (794 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACVRL1	ENG	ENSPCOP00000022826	ENSPCOP00000020963	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Endoglin.	0.893
ACVRL1	GDF2	ENSPCOP00000022826	ENSPCOP00000028801	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Growth differentiation factor 2.	0.995
ACVRL1	NGFR	ENSPCOP00000022826	ENSPCOP00000014421	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Nerve growth factor receptor.	0.445
ACVRL1	PTPRM	ENSPCOP00000022826	ENSPCOP00000008681	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Protein tyrosine phosphatase receptor type M.	0.478
ACVRL1	STAT1	ENSPCOP00000022826	ENSPCOP00000008015	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Signal transducer and activator of transcription.	0.431
ACVRL1	TGFBR1	ENSPCOP00000022826	ENSPCOP00000018681	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.817
AIMP1	ATP5F1A	ENSPCOP00000000497	ENSPCOP00000011077	Aminoacyl tRNA synthetase complex interacting multifunctional protein 1.	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.412
APOE	CAV1	ENSPCOP00000010240	ENSPCOP00000025045	Apolipoprotein E.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.414
APOE	TNF	ENSPCOP00000010240	ENSPCOP00000015346	Apolipoprotein E.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.449
ATOH8	THBS1	ENSPCOP00000021682	ENSPCOP00000024785	Atonal bHLH transcription factor 8.	Thrombospondin 1.	0.618
ATP5F1A	AIMP1	ENSPCOP00000011077	ENSPCOP00000000497	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Aminoacyl tRNA synthetase complex interacting multifunctional protein 1.	0.412
ATP5F1A	ATP5IF1	ENSPCOP00000011077	ENSPCOP00000031399	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	ATP synthase inhibitory factor subunit 1.	0.959
ATP5IF1	ATP5F1A	ENSPCOP00000031399	ENSPCOP00000011077	ATP synthase inhibitory factor subunit 1.	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.959
CAV1	APOE	ENSPCOP00000025045	ENSPCOP00000010240	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Apolipoprotein E.	0.414
CAV1	CAV2	ENSPCOP00000025045	ENSPCOP00000026838	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.997
CAV1	TGFBR1	ENSPCOP00000025045	ENSPCOP00000018681	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.434
CAV2	CAV1	ENSPCOP00000026838	ENSPCOP00000025045	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.997
COL4A3	THBS1	ENSPCOP00000009214	ENSPCOP00000024785	Collagen type IV alpha 3 chain.	Thrombospondin 1.	0.426
DLL4	FLT1	ENSPCOP00000003864	ENSPCOP00000016838	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.451
DLL4	TNF	ENSPCOP00000003864	ENSPCOP00000015346	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.402