(50 nodes) Morphogenesis of an epithelial sheet network (Propithecus coquereli)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	DAG1	Dystroglycan 1. (895 aa)
	WNT7B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	WNT7A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (190 aa)
	NOTCH2	Notch receptor 2. (2471 aa)
	LAMA1	Laminin subunit alpha 1. (2945 aa)
	FLNA	Filamin A. (2647 aa)
	BMP7	Bone morphogenetic protein 7. (431 aa)
	MEGF8	Multiple EGF like domains 8. (2804 aa)
	DLL4	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
	FLRT3	Fibronectin leucine rich transmembrane protein 3. (649 aa)
	NOTCH1	Notch receptor 1. (2420 aa)
	JAG1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
	ITGA5	Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1041 aa)
	HBEGF	Heparin binding EGF like growth factor. (208 aa)
	ENSPCOP00000006549	Uncharacterized protein. (199 aa)
	DVL2	Dishevelled segment polarity protein 2. (736 aa)
	RHOA	Ras homolog family member A. (193 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
	MMP12	Matrix metallopeptidase 12. (469 aa)
	PHACTR4	Phosphatase and actin regulator. (702 aa)
	ARHGAP35	Rho GTPase activating protein 35. (1510 aa)
	SOS1	SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
	AJUBA	Ajuba LIM protein. (539 aa)
	TMEFF2	Transmembrane protein with EGF like and two follistatin like domains 2. (365 aa)
	BMP5	Bone morphogenetic protein 5. (379 aa)
	RHOC	Ras homolog family member C. (193 aa)
	MPP5	Membrane palmitoylated protein 5; Belongs to the MAGUK family. (627 aa)
	HOXB2	Homeobox B2. (354 aa)
	SOX11	Transcription factor SOX. (442 aa)
	TBX20	T-box transcription factor 20. (447 aa)
	LRG1	Leucine rich alpha-2-glycoprotein 1. (347 aa)
	MRTFA	Myocardin related transcription factor A. (968 aa)
	CEACAM1	Uncharacterized protein. (523 aa)
	DDR1	Discoidin domain receptor tyrosine kinase 1. (913 aa)
	TOR1A	Torsin. (332 aa)
	CCN1	Cellular communication network factor 1. (381 aa)
	SRF	Serum response factor. (508 aa)
	PDPN	Podoplanin. (211 aa)
	COL5A1	Collagen type V alpha 1 chain. (1843 aa)
	HOXB4	Homeobox B4. (251 aa)
	LIN7C	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (197 aa)
	ACVRL1	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
	ARHGAP24	Rho GTPase activating protein 24. (749 aa)
	ARHGAP12	Rho GTPase activating protein 12. (851 aa)
	ENSPCOP00000025645	Uncharacterized protein. (162 aa)
	DVL1	Dishevelled segment polarity protein 1. (722 aa)
	CD44	CD44 molecule (Indian blood group). (746 aa)
	PDCD10	Programmed cell death 10. (186 aa)
	CARMIL2	Capping protein regulator and myosin 1 linker 2. (1399 aa)
	ADAM17	ADAM metallopeptidase domain 17. (757 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACVRL1	BMP5	ENSPCOP00000022826	ENSPCOP00000010725	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Bone morphogenetic protein 5.	0.877
ACVRL1	BMP7	ENSPCOP00000022826	ENSPCOP00000003744	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Bone morphogenetic protein 7.	0.877
ACVRL1	DVL1	ENSPCOP00000022826	ENSPCOP00000026920	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Dishevelled segment polarity protein 1.	0.438
ACVRL1	DVL2	ENSPCOP00000022826	ENSPCOP00000006637	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Dishevelled segment polarity protein 2.	0.438
ACVRL1	ENSPCOP00000025645	ENSPCOP00000022826	ENSPCOP00000025645	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Uncharacterized protein.	0.534
ACVRL1	RHOA	ENSPCOP00000022826	ENSPCOP00000006647	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Ras homolog family member A.	0.534
ACVRL1	RHOC	ENSPCOP00000022826	ENSPCOP00000011003	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Ras homolog family member C.	0.534
ADAM17	DLL4	ENSPCOP00000030128	ENSPCOP00000003864	ADAM metallopeptidase domain 17.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.493
ADAM17	HBEGF	ENSPCOP00000030128	ENSPCOP00000006195	ADAM metallopeptidase domain 17.	Heparin binding EGF like growth factor.	0.833
ADAM17	JAG1	ENSPCOP00000030128	ENSPCOP00000004920	ADAM metallopeptidase domain 17.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.588
ADAM17	NOTCH1	ENSPCOP00000030128	ENSPCOP00000004691	ADAM metallopeptidase domain 17.	Notch receptor 1.	0.901
ADAM17	NOTCH2	ENSPCOP00000030128	ENSPCOP00000003213	ADAM metallopeptidase domain 17.	Notch receptor 2.	0.874
AJUBA	FLNA	ENSPCOP00000009524	ENSPCOP00000003724	Ajuba LIM protein.	Filamin A.	0.630
ARHGAP12	ARHGAP35	ENSPCOP00000025366	ENSPCOP00000008940	Rho GTPase activating protein 12.	Rho GTPase activating protein 35.	0.432
ARHGAP12	ENSPCOP00000025645	ENSPCOP00000025366	ENSPCOP00000025645	Rho GTPase activating protein 12.	Uncharacterized protein.	0.617
ARHGAP12	LIN7C	ENSPCOP00000025366	ENSPCOP00000022308	Rho GTPase activating protein 12.	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	0.414
ARHGAP12	RHOA	ENSPCOP00000025366	ENSPCOP00000006647	Rho GTPase activating protein 12.	Ras homolog family member A.	0.617
ARHGAP12	RHOC	ENSPCOP00000025366	ENSPCOP00000011003	Rho GTPase activating protein 12.	Ras homolog family member C.	0.617
ARHGAP24	ENSPCOP00000025645	ENSPCOP00000000234	ENSPCOP00000025645	Rho GTPase activating protein 24.	Uncharacterized protein.	0.607
ARHGAP24	FLNA	ENSPCOP00000000234	ENSPCOP00000003724	Rho GTPase activating protein 24.	Filamin A.	0.716