59 items (Propithecus coquereli) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	KLF4	Uncharacterized protein. (486 aa)
	NKX2-2	NK2 homeobox 2. (273 aa)
	YAP1	Uncharacterized protein. (504 aa)
	NR5A2	Nuclear receptor subfamily 5 group A member 2. (541 aa)
	NKX6-3	Homeobox domain-containing protein. (263 aa)
	NOTCH1	Notch receptor 1. (2420 aa)
	DLL1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
	PDX1	Pancreatic and duodenal homeobox 1. (282 aa)
	GATA2	GATA binding protein 2. (445 aa)
	FGF8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
	HIF1A	Hypoxia inducible factor 1 subunit alpha. (826 aa)
	PDPK1	3-phosphoinositide dependent protein kinase 1. (558 aa)
	LOC105817239	LIM zinc-binding domain-containing protein. (89 aa)
	CDH2	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
	LOC105822779	Uncharacterized protein. (325 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
	TP63	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
	BMP2	Bone morphogenetic protein 2. (395 aa)
	FGFR2	Fibroblast growth factor receptor. (797 aa)
	SPDEF	SAM pointed domain containing ETS transcription factor. (335 aa)
	SOX9	SRY-box transcription factor 9. (505 aa)
	PAX6	Paired box 6. (453 aa)
	HNF4A	Hepatocyte nuclear factor 4 alpha. (474 aa)
	BMP6	Bone morphogenetic protein 6. (509 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	SMO	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (789 aa)
	PGR	Nuclear receptor domain-containing protein. (592 aa)
	NKX6-1	NK6 homeobox 1. (367 aa)
	GATA6	GATA binding protein 6. (593 aa)
	CDK6	Cyclin dependent kinase 6. (263 aa)
	IL31RA	Interleukin 31 receptor A. (642 aa)
	RFX6	Regulatory factor X6. (892 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
	ENSPCOP00000025005	Uncharacterized protein. (351 aa)
	RARA	Retinoic acid receptor alpha. (472 aa)
	GDF11	Growth differentiation factor 11. (404 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	RARB	Retinoic acid receptor beta. (448 aa)
	WNT4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	SIDT2	SID1 transmembrane family member 2. (882 aa)
	RFX3	Regulatory factor X3. (760 aa)
	CLCN2	Chloride channel protein. (902 aa)
	EXT1	Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
	SLC9A4	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (797 aa)
	MEN1	Menin 1. (616 aa)
	NKX6-2	NK6 homeobox 2. (277 aa)
	AGR2	Anterior gradient 2, protein disulphide isomerase family member. (122 aa)
	HOXA5	Homeobox A5. (270 aa)
	LHX3	Uncharacterized protein. (458 aa)
	PAX4	Paired box 4. (349 aa)
	PERCC1	Uncharacterized protein. (259 aa)
	RARG	Retinoic acid receptor gamma. (458 aa)
	ENSPCOP00000014590	Uncharacterized protein. (118 aa)
	PROX1	Prospero homeobox 1. (737 aa)
	WDR77	WD repeat domain 77. (293 aa)
	FASN	Fatty acid synthase. (2506 aa)
	BMP5	Bone morphogenetic protein 5. (379 aa)
	NFIB	Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
	FOXA1	Forkhead box A1. (472 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGR2	FOXA1	ENSPCOP00000017527	ENSPCOP00000011466	Anterior gradient 2, protein disulphide isomerase family member.	Forkhead box A1.	0.551
AGR2	SPDEF	ENSPCOP00000017527	ENSPCOP00000029764	Anterior gradient 2, protein disulphide isomerase family member.	SAM pointed domain containing ETS transcription factor.	0.622
BMP2	BMP4	ENSPCOP00000030823	ENSPCOP00000028335	Bone morphogenetic protein 2.	Bone morphogenetic protein 4.	0.896
BMP2	BMP5	ENSPCOP00000030823	ENSPCOP00000010725	Bone morphogenetic protein 2.	Bone morphogenetic protein 5.	0.831
BMP2	BMP6	ENSPCOP00000030823	ENSPCOP00000028377	Bone morphogenetic protein 2.	Bone morphogenetic protein 6.	0.936
BMP2	CTNNB1	ENSPCOP00000030823	ENSPCOP00000022753	Bone morphogenetic protein 2.	Catenin beta 1.	0.469
BMP2	FGF8	ENSPCOP00000030823	ENSPCOP00000012774	Bone morphogenetic protein 2.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.455
BMP2	GATA6	ENSPCOP00000030823	ENSPCOP00000027588	Bone morphogenetic protein 2.	GATA binding protein 6.	0.531
BMP2	NOTCH1	ENSPCOP00000030823	ENSPCOP00000004691	Bone morphogenetic protein 2.	Notch receptor 1.	0.405
BMP2	SMO	ENSPCOP00000030823	ENSPCOP00000028237	Bone morphogenetic protein 2.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.404
BMP2	SOX9	ENSPCOP00000030823	ENSPCOP00000029276	Bone morphogenetic protein 2.	SRY-box transcription factor 9.	0.454
BMP4	BMP2	ENSPCOP00000028335	ENSPCOP00000030823	Bone morphogenetic protein 4.	Bone morphogenetic protein 2.	0.896
BMP4	BMP5	ENSPCOP00000028335	ENSPCOP00000010725	Bone morphogenetic protein 4.	Bone morphogenetic protein 5.	0.831
BMP4	BMP6	ENSPCOP00000028335	ENSPCOP00000028377	Bone morphogenetic protein 4.	Bone morphogenetic protein 6.	0.936
BMP4	CTNNB1	ENSPCOP00000028335	ENSPCOP00000022753	Bone morphogenetic protein 4.	Catenin beta 1.	0.472
BMP4	FGF8	ENSPCOP00000028335	ENSPCOP00000012774	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.470
BMP4	FGFR2	ENSPCOP00000028335	ENSPCOP00000030338	Bone morphogenetic protein 4.	Fibroblast growth factor receptor.	0.438
BMP4	GATA6	ENSPCOP00000028335	ENSPCOP00000027588	Bone morphogenetic protein 4.	GATA binding protein 6.	0.535
BMP4	NOTCH1	ENSPCOP00000028335	ENSPCOP00000004691	Bone morphogenetic protein 4.	Notch receptor 1.	0.405
BMP4	SMO	ENSPCOP00000028335	ENSPCOP00000028237	Bone morphogenetic protein 4.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.404