20 items (Propithecus coquereli) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SYK	Spleen associated tyrosine kinase. (637 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	MKRN2	Makorin ring finger protein 2. (416 aa)
	IL10	Interleukin 10. (178 aa)
	ENSPCOP00000000722	Protein kinase domain-containing protein. (67 aa)
	LYN	Tyrosine-protein kinase. (512 aa)
	NPY5R	Neuropeptide Y receptor Y5. (446 aa)
	NOD2	Nucleotide binding oligomerization domain containing 2. (1040 aa)
	ENSPCOP00000029247	Proteasome subunit beta; Belongs to the peptidase T1B family. (257 aa)
	NLRP6	NLR family pyrin domain containing 6. (890 aa)
	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1304 aa)
	IL20RB	Interleukin 20 receptor subunit beta. (312 aa)
	PSMB4	Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
	SRC	Tyrosine-protein kinase. (543 aa)
	FGR	Tyrosine-protein kinase. (495 aa)
	SELENOS	Selenoprotein S. (187 aa)
	IL12B	Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (326 aa)
	TREM2	Triggering receptor expressed on myeloid cells 2. (224 aa)
	FURIN	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (798 aa)
	RHBDF2	Rhomboid 5 homolog 2. (829 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPCOP00000000722	FGR	ENSPCOP00000000722	ENSPCOP00000018420	Protein kinase domain-containing protein.	Tyrosine-protein kinase.	0.894
ENSPCOP00000000722	FYN	ENSPCOP00000000722	ENSPCOP00000008529	Protein kinase domain-containing protein.	Tyrosine-protein kinase.	0.990
ENSPCOP00000000722	LYN	ENSPCOP00000000722	ENSPCOP00000024889	Protein kinase domain-containing protein.	Tyrosine-protein kinase.	0.887
ENSPCOP00000000722	PLCG1	ENSPCOP00000000722	ENSPCOP00000024732	Protein kinase domain-containing protein.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.723
ENSPCOP00000000722	SRC	ENSPCOP00000000722	ENSPCOP00000018583	Protein kinase domain-containing protein.	Tyrosine-protein kinase.	0.959
ENSPCOP00000000722	SYK	ENSPCOP00000000722	ENSPCOP00000009462	Protein kinase domain-containing protein.	Spleen associated tyrosine kinase.	0.912
ENSPCOP00000000722	TREM2	ENSPCOP00000000722	ENSPCOP00000012504	Protein kinase domain-containing protein.	Triggering receptor expressed on myeloid cells 2.	0.422
FGR	ENSPCOP00000000722	ENSPCOP00000018420	ENSPCOP00000000722	Tyrosine-protein kinase.	Protein kinase domain-containing protein.	0.894
FGR	LYN	ENSPCOP00000018420	ENSPCOP00000024889	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.942
FGR	PLCG1	ENSPCOP00000018420	ENSPCOP00000024732	Tyrosine-protein kinase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.604
FGR	SRC	ENSPCOP00000018420	ENSPCOP00000018583	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.897
FGR	SYK	ENSPCOP00000018420	ENSPCOP00000009462	Tyrosine-protein kinase.	Spleen associated tyrosine kinase.	0.813
FGR	TREM2	ENSPCOP00000018420	ENSPCOP00000012504	Tyrosine-protein kinase.	Triggering receptor expressed on myeloid cells 2.	0.455
FURIN	SYK	ENSPCOP00000011730	ENSPCOP00000009462	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.	Spleen associated tyrosine kinase.	0.404
FYN	ENSPCOP00000000722	ENSPCOP00000008529	ENSPCOP00000000722	Tyrosine-protein kinase.	Protein kinase domain-containing protein.	0.990
FYN	LYN	ENSPCOP00000008529	ENSPCOP00000024889	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.958
FYN	PLCG1	ENSPCOP00000008529	ENSPCOP00000024732	Tyrosine-protein kinase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.725
FYN	SRC	ENSPCOP00000008529	ENSPCOP00000018583	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.994
FYN	SYK	ENSPCOP00000008529	ENSPCOP00000009462	Tyrosine-protein kinase.	Spleen associated tyrosine kinase.	0.887
FYN	TREM2	ENSPCOP00000008529	ENSPCOP00000012504	Tyrosine-protein kinase.	Triggering receptor expressed on myeloid cells 2.	0.516